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Found 1 matching record:

Displaying record number 57930

HXB2 Location  gp160(848-856)   gp160 Epitope Map
View variants at this location
Epitope RQGLERALL   Epitope Alignment
Variants
RQGLERvLL   inferred escape
RQGLERAfL   inferred escape
Species (MHC/HLA human(B8)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2659
Epitope Seq.  RQGLERALL
Variant Seq.  RQGLERvLL
Mutations A/V
Epitope Location A7V
HXB2 Location A854V
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Longitudinal study
Note Founder sequence RQGLERALL was replaced by day 44 post-seroconversion by two mutually exclusive variants, RQGLERvLL and RQGLERAfL. EliSpot response to the original peptide increased from 0 at day 7 to 1310 at day 127


Variant ID.  2660
Epitope Seq.  RQGLERALL
Variant Seq.  RQGLERAfL
Mutations L/F
Epitope Location L8F
HXB2 Location L855F
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Longitudinal study
Note Founder sequence RQGLERALL was replaced by day 44 post-seroconversion by two mutually exclusive variants, RQGLERvLL and RQGLERAfL. EliSpot response to the original peptide increased from 0 at day 7 to 1310 at day 127

References

Herbeck2011 Joshua T. Herbeck, Morgane Rolland, Yi Liu, Sherry McLaughlin, John McNevin, Hong Zhao, Kim Wong, Julia N. Stoddard, Dana Raugi, Stephanie Sorensen, Indira Genowati, Brian Birditt, Angela McKay, Kurt Diem, Brandon S. Maust, Wenjie Deng, Ann C. Collier, Joanne D. Stekler, M. Juliana McElrath, and James I. Mullins. Demographic Processes Affect HIV-1 Evolution in Primary Infection before the Onset of Selective Processes. J. Virol., 85(15):7523-7534, Aug 2011. PubMed ID: 21593162. Show all entries for this paper.


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