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Found 1 matching record:

Displaying record number 57824

HXB2 Location  Nef(105-114)   Nef Epitope Map
View variants at this location
Epitope RRQDILDLWI   Epitope Alignment
Variants
RgQDILDLWI   unclear
ReQDILDLWI   unclear
Species (MHC/HLA human(B*27)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2661
Epitope Seq.  RRQDILDLWI
Variant Seq.  RgQDILDLWI
Mutations R/G
Epitope Location R2G
HXB2 Location R106G
Mutation Type ?: unclear
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Tetramer binding
Note Mutation is in anchor position, stated as possible escape mutant from sequence data, carried by 1/16 patients.


Variant ID.  2662
Epitope Seq.  RRQDILDLWI
Variant Seq.  ReQDILDLWI
Mutations R/E
Epitope Location R2E
HXB2 Location R106E
Mutation Type ?: unclear
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Tetramer binding
Note Mutation is in anchor position, stated as possible escape mutant from sequence data, carried by 1/16 patients.

References

Ammaranond2011 Palanee Ammaranond, David J. van Bockel, Kathy Petoumenos, Marylin McMurchie, Robert Finlayson, Melanie G. Middleton, Miles P. Davenport, Vanessa Venturi, Kazuo Suzuki, Linda Gelgor, John M. Kaldor, David A. Cooper, and Anthony D. Kelleher. HIV Immune Escape at an Immunodominant Epitope in HLA-B*27-Positive Individuals Predicts Viral Load Outcome. J. Immunol., 186(1):479-488, 1 Jan 2011. PubMed ID: 21115730. Show all entries for this paper.


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