Found 1 matching record:
HXB2 Location | Nef(71-81) | Nef Epitope Map
View variants at this location |
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Epitope |
RPQVPLRPMTY
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Epitope Alignment | ||||
Variants |
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Epitope Name | RY11 | |||||
Species (MHC/HLA) | human(B*35) |
Showing all: 1 variant(s).
Variant ID. | 2634 |
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Epitope Seq. | RPQVPLRPMTY |
Variant Seq. | tPQVPLRPMTY |
Mutations | R/T |
Epitope Location | R1T |
HXB2 Location | R71T |
Mutation Type | DR: diminished response |
Note | Variant to RY11, tPQVPLRPMTY, is seen to reduce antiviral CTL activity by a decline in proliferative capacity, Ueno et al., J. Immunol., 178:5513-23 (2007). |
Motozono2010 Chihiro Motozono, Philip Mwimanzi, and Takamasa Ueno. Dynamic Interplay between Viral Adaptation and Immune Recognition during HIV-1 Infection. Protein Cell, 1(6):514-519, Jun 2010. PubMed ID: 21204005. Show all entries for this paper.
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