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Found 1 matching record:

Displaying record number 57413

HXB2 Location  Gag(308-316)   Gag Epitope Map
View variants at this location
Epitope QASQEVKNW   Epitope Alignment
Variants
QAStEVKNW   observed variant
QASQdVKNW   observed variant
Epitope Name QW9
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2358
Epitope Seq.  QASQEVKNW
Variant Seq.  QAStEVKNW
Mutations Q/T
Epitope Location Q4T
HXB2 Location Q311T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Two patients, both with low viral load, positive for HLAs B*5703 and B*5701 respectively, carried variant QAStEVKNW from enrollment on.


Variant ID.  2359
Epitope Seq.  QASQEVKNW
Variant Seq.  QASQdVKNW
Mutations E/D
Epitope Location E5D
HXB2 Location E312D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5702 positive patient with low viral carried this variant from enrollment on; one HLA-B*5701 positive patient with increased viremia also carried it from enrollment.

References

Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.


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