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Displaying record number 56302

HXB2 Location Nef(101-109) Nef Epitope Map
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Epitope

IHSQRRQDI

Epitope Alignment

Variants

IySQkRQDI susceptible form

Species (MHC/HLA) human(A24)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`161`
Epitope Seq.	`IHSQRRQDI`
Variant Seq.	`IySQkRQDI`
Mutations	H/Y R/K
Epitope Location	H2Y R5K
HXB2 Location	H102Y R105K
Mutation Type	SF: susceptible form
Method	Flow cytometric T-cell cytokine assay
Note	IHSQRRQDI, elicited a response in 1 patient. Patient autologous sequence was IySQkRQDI, which was exclusively targeted over the consensus form IHSQRRQDI.

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.