HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 56298

HXB2 Location  Gag(266-273)   Gag Epitope Map
View variants at this location
Epitope IILGLNKI   Epitope Alignment
Variants
ImLGLNKI   observed variant
Species (MHC/HLA human(A2, A3)

Variant Details

Showing all: 1 variant(s).


Variant ID.  160
Epitope Seq.  IILGLNKI
Variant Seq.  ImLGLNKI
Mutations I/M
Epitope Location I2M
HXB2 Location I267M
Mutation Type OV: observed variant
Method Flow cytometric T-cell cytokine assay
Note IILGLNKI, elicited a response in 1 patient. The patient autologous sequence was ImLGLNKI.

References

Daucher2008 Marybeth Daucher, David A. Price, Jason M. Brenchley, Laurie Lamoreaux, Julia A. Metcalf, Catherine Rehm, Elizabeth Nies-Kraske, Elizabeth Urban, Christian Yoder, Diane Rock, Julie Gumkowski, Michael R. Betts, Mark R. Dybul, and Daniel C. Douek. Virological Outcome after Structured Interruption of Antiretroviral Therapy for Human Immunodeficiency Virus Infection Is Associated with the Functional Profile of Virus-Specific CD8+ T Cells. J. Virol., 82(8):4102-4114, Apr 2008. PubMed ID: 18234797. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health