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Displaying record number 55919

HXB2 Location Gag(349-359) Gag Epitope Map
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Epitope

ACQGVGGPSHK

Epitope Alignment

Variants

ACQGVGGPgHK observed variant

Epitope Name AK11(p24)

Species (MHC/HLA) human

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1914`
Epitope Seq.	`ACQGVGGPSHK`
Variant Seq.	`ACQGVGGPgHK`
Mutations	S/G
Epitope Location	S9G
HXB2 Location	S357G
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Sequence
Note	Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope. This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A11 restricted.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.