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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 55639

HXB2 Location  Gag(142-155)   Gag Epitope Map
View variants at this location
Epitope MVHQSMSPRTLNAW   Epitope Alignment
Variants
MVHQplSPRTLNAW   subtype-specific susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  16
Epitope Seq.  MVHQSMSPRTLNAW
Variant Seq.  MVHQplSPRTLNAW
Mutations S/P M/L
Epitope Location S5P M6L
HXB2 Location S146P M147L
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype CRF02_AG
Variant Subtype A
Method CD8 T-cell Elispot - IFNy
Note 2 subjects responded to peptide MVHQSMSPRTLNAW from subtype CRF02_AG, and 1 of the 2 responded to peptide MVHQplSPRTLNAW from subtype A.

References

Aidoo2008 M. Aidoo, S. Sawadogo, E. C. Bile, C. Yang, J. N. Nkengasong, and J. M. McNicholl. Viral, HLA and T Cell Elements in Cross-Reactive Immune Responses to HIV-1 Subtype A, CRF01\_AE and CRF02\_AG Vaccine Sequence in Ivorian Blood Donors. Vaccine, 26(37):4830-4839, 2 Sep 2008. PubMed ID: 18640166. Show all entries for this paper.


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