Found 1 matching record:
HXB2 Location | Gag(147-155) | Gag Epitope Map
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Epitope |
ISPRTLNAW
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Variants |
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Epitope Name | ISP | ||||||||||||||||||||||||||
Species (MHC/HLA) | human(B*57:01) |
Showing all: 8 variant(s).
Variant ID. | 1789 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | raPRTLNAW |
Mutations | I/R S/A |
Epitope Location | I1R S2A |
HXB2 Location | I147R S148A |
Mutation Type | NSF: non-susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | None of the patients tested recognized the variant. |
Variant ID. | 1790 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | mSPRTLNAW |
Mutations | I/M |
Epitope Location | I1M |
HXB2 Location | I147M |
Mutation Type | NSF: non-susceptible form SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant, some did not. |
Variant ID. | 1791 |
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Epitope Seq. | ISPRTLNAW |
Variant Seq. | vSPRTLNAW |
Mutations | I/V |
Epitope Location | I1V |
HXB2 Location | I147V |
Mutation Type | NSF: non-susceptible form SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant, some did not. |
Variant ID. | 1792 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | ltPRTLNAW |
Mutations | I/L S/T |
Epitope Location | I1L S2T |
HXB2 Location | I147L S148T |
Mutation Type | NSF: non-susceptible form SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant, some did not. |
Variant ID. | 1793 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | vtPRTLNAW |
Mutations | I/V S/T |
Epitope Location | I1V S2T |
HXB2 Location | I147V S148T |
Mutation Type | NSF: non-susceptible form SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant, some did not. |
Variant ID. | 1794 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | ISaRTLNAW |
Mutations | P/A |
Epitope Location | P3A |
HXB2 Location | P149A |
Mutation Type | NSF: non-susceptible form SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant, some did not. |
Variant ID. | 1795 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | IaPRTLNAr |
Mutations | S/A W/R |
Epitope Location | S2A W9R |
HXB2 Location | S148A W155R |
Mutation Type | NSF: non-susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | None of the patients tested recognized the variant. |
Variant ID. | 1796 |
---|---|
Epitope Seq. | ISPRTLNAW |
Variant Seq. | lSPRTLNAW |
Mutations | I/L |
Epitope Location | I1L |
HXB2 Location | I147L |
Mutation Type | DR: diminished response SF: susceptible form |
Method | CD8 T-cell Elispot - IFNy, Tetramer binding |
Note | Some patients recognized the variant at the level of the index peptide, some had diminished response. |
Turnbull2006 Emma L. Turnbull, A. Ross Lopes, Nicola A. Jones, David Cornforth, Phillipa Newton, Diana Aldam, Pierre Pellegrino, Jo Turner, Ian Williams, Craig M. Wilson, Paul A. Goepfert, Mala K. Maini, and Persephone Borrow. HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently. J. Immunol., 176(10):6130-6146, 15 May 2006. PubMed ID: 16670322. Show all entries for this paper.
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