HIV molecular immunology database
Found 1 matching record:
HXB2 Location | Gag(71-79) | Gag Epitope Map
View variants at this location |
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Epitope |
GSEELRSLY
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Epitope Alignment | |||||||
Variants |
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Epitope Name | GY9 | ||||||||
Species (MHC/HLA) | human(A*01) |
Showing all: 2 variant(s).
Variant ID. | 627 |
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Epitope Seq. | GSEELRSLY |
Variant Seq. | GSEELRSLf |
Mutations | Y/F |
Epitope Location | Y9F |
HXB2 Location | Y79F |
Mutation Type | E: escape documented in this paper |
Note | The variant was present in most of the clones by week 139 and was not recognized by the CTLs. |
Variant ID. | 628 |
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Epitope Seq. | GSEELRSLY |
Variant Seq. | GSEELRSLc |
Mutations | Y/C |
Epitope Location | Y9C |
HXB2 Location | Y79C |
Mutation Type | IE: inferred escape |
Note | Author tabulates this minor variant (1/12) found in patient OP428 at week 63 as viral escape. No CTL response. |
Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.