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Found 1 matching record:

Displaying record number 54577

HXB2 Location  Gag(71-79)   Gag Epitope Map
View variants at this location
Epitope GSEELRSLY   Epitope Alignment
Variants
GSEELRSLf   escape documented in this paper
GSEELRSLc   inferred escape
Epitope Name GY9
Species (MHC/HLA human(A*01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  627
Epitope Seq.  GSEELRSLY
Variant Seq.  GSEELRSLf
Mutations Y/F
Epitope Location Y9F
HXB2 Location Y79F
Mutation Type E: escape documented in this paper
Note The variant was present in most of the clones by week 139 and was not recognized by the CTLs.


Variant ID.  628
Epitope Seq.  GSEELRSLY
Variant Seq.  GSEELRSLc
Mutations Y/C
Epitope Location Y9C
HXB2 Location Y79C
Mutation Type IE: inferred escape
Note Author tabulates this minor variant (1/12) found in patient OP428 at week 63 as viral escape. No CTL response.

References

Karlsson2007 Annika C. Karlsson, Astrid K. N. Iversen, Joan M. Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J. McMichael, Miles P. Davenport, Frederick M. Hecht, and Douglas F. Nixon. Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape. PLoS ONE, 2:e225, 2007. PubMed ID: 17311088. Show all entries for this paper.


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