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Displaying record number 54544

HXB2 Location Nef(77-85) Nef Epitope Map
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Epitope

RPMTYKGAL

Epitope Alignment

Variants

RPMTYraAr susceptible form

Epitope Name RL9

Species (MHC/HLA) human(B7 supertype)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1029`
Epitope Seq.	`RPMTYKGAL`
Variant Seq.	`RPMTYraAr`
Mutations	K/R G/A L/R
Epitope Location	K6R G7A L9R
HXB2 Location	K82R G83A L85R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Sequence
Note	This variant was found by challenge of 23 subjects with a novel Nef potential T-cell epitope panel in Subtype B.

References

Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.