HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54544

HXB2 Location  Nef(77-85)   Nef Epitope Map
View variants at this location
Epitope RPMTYKGAL   Epitope Alignment
RPMTYraAr   susceptible form
Epitope Name RL9
Species (MHC/HLA human(B7 supertype)

Variant Details

Showing all: 1 variant(s).

Variant ID.  1029
Epitope Seq.  RPMTYKGAL
Variant Seq.  RPMTYraAr
Mutations K/R G/A L/R
Epitope Location K6R G7A L9R
HXB2 Location K82R G83A L85R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This variant was found by challenge of 23 subjects with a novel Nef potential T-cell epitope panel in Subtype B.


Malhotra2007a Uma Malhotra, Fusheng Li, Jessica Nolin, Megan Allison, Hong Zhao, James I. Mullins, Steve Self, and M. Juliana McElrath. Enhanced Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Nef-Specific T Cells Recognizing Multiple Variants in Early HIV-1 Infection. J. Virol., 81(10):5225-5237, May 2007. PubMed ID: 17329342. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health