HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54534

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
lSPRTLNAW   subtype-specific susceptible form
Epitope Name IW9
Species (MHC/HLA human(B57)

Variant Details

Showing all: 1 variant(s).

Variant ID.  1021
Epitope Seq.  ISPRTLNAW
Variant Seq.  lSPRTLNAW
Mutations I/L
Epitope Location I1L
HXB2 Location I147L
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype A
Method CD8 T-cell Elispot - IFNy
Note Cross-recognition of this variant is seen with both C- and A-clades. Anchor residues are at positions 2 and 9; while the A-clade variant contains a change at position 1 to lSPRTLNAW.


Malhotra2007 Uma Malhotra, Jessica Nolin, James I. Mullins, and M. Juliana McElrath. Comprehensive Epitope Analysis of Cross-Clade Gag-Specific T-Cell Responses in Individuals with Early HIV-1 Infection in the US Epidemic. Vaccine, 25(2):381-390, 4 Jan 2007. PubMed ID: 17112643. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health