HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54163

HXB2 Location  gp160(217-226)   gp160 Epitope Map
View variants at this location
Epitope YCAPAGFAIL   Epitope Alignment
YCAPAGFAIi   escape documented in this paper
Epitope Name YL10
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.  988
Epitope Seq.  YCAPAGFAIL
Variant Seq.  YCAPAGFAIi
Mutations L/I
Epitope Location L10I
HXB2 Location L226I
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy
Note Last position (10)in the epitope had potentially experienced positive selection. The variant was full escape, as it was not recognized by CTLs.


Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.

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