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Found 1 matching record:

Displaying record number 54159

HXB2 Location  Tat(30-37)   Tat Epitope Map
View variants at this location
Epitope CCFHCQVC   Epitope Alignment
Variants
CClHCQVC   escape documented in this paper
CCFHCQsC   escape documented in this paper
Epitope Name CC8
Species (MHC/HLA human(C*12:03)

Variant Details

Showing all: 2 variant(s).


Variant ID.  973
Epitope Seq.  CCFHCQVC
Variant Seq.  CClHCQVC
Mutations F/L
Epitope Location F3L
HXB2 Location F32L
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy
Note Position 3 in the epitope had potentially experienced positive selection. The variant was full escape, as it was not recognized by CTLs.


Variant ID.  974
Epitope Seq.  CCFHCQVC
Variant Seq.  CCFHCQsC
Mutations V/S
Epitope Location V7S
HXB2 Location V36S
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy
Note Position 3 in the epitope had potentially experienced positive selection. The variant was full escape, as it was not recognized by CTLs.

References

Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.


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