HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(11-19) | Gag Epitope Map
View variants at this location |
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| Epitope |
GELDRWEKI
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | GI9 | |||||
| Species (MHC/HLA) | human(B*40) | |||||
Showing all: 1 variant(s).
| Variant ID. | 1569 |
|---|---|
| Epitope Seq. | GELDRWEKI |
| Variant Seq. | GELDRWkKI |
| Mutations | E/K |
| Epitope Location | E7K |
| HXB2 Location | E17K |
| Mutation Type | DR: diminished response LE: literature escape |
| Method | CD8 T-cell Elispot - IFNy, Sequence |
| Note | This variant from the HXB2 sequence was present in the restricting HLA-B40-carrying mother, M-1002, but was never detected in her non-HLA-B40-carrying infant, P-1031. Decreased recognition of the E17K variant relative to the index epitope was seen in the mother. |
Sanchez-Merino2005 Victor Sanchez-Merino, Siwei Nie, and Katherine Luzuriaga. HIV-1-Specific CD8+ T Cell Responses and Viral Evolution in Women and Infants. J. Immunol., 175(10):6976-6986, 15 Nov 2005. PubMed ID: 16272358. Show all entries for this paper.