HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Nef(86-94) | Nef Epitope Map
View variants at this location |
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| Epitope |
DLSHFLKEK
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Epitope Alignment | ||||||||||||||||
| Variants |
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| Species (MHC/HLA) | human(A*03, A*11) | |||||||||||||||||
Showing all: 5 variant(s).
| Variant ID. | 855 |
|---|---|
| Epitope Seq. | DLSHFLKEK |
| Variant Seq. | DLSfFLKEK |
| Mutations | H/F |
| Epitope Location | H4F |
| HXB2 Location | H89F |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | CRF01_AE |
| Method | Computer prediction |
| Note | This was the most common variant in CRF01 (18/23 patients). It had the same binding score to HLA as the wt epitope. |
| Variant ID. | 856 |
|---|---|
| Epitope Seq. | DLSHFLKEK |
| Variant Seq. | DLSfFLiEK |
| Mutations | H/F K/I |
| Epitope Location | H4F K7I |
| HXB2 Location | H89F K92I |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | CRF01_AE |
| Note | Variant found in 1/23 patients infected with CRF01_AE. |
| Variant ID. | 857 |
|---|---|
| Epitope Seq. | DLSHFLKEK |
| Variant Seq. | DLSfFLrEK |
| Mutations | H/F K/R |
| Epitope Location | H4F K7R |
| HXB2 Location | H89F K92R |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | CRF01_AE |
| Note | Variant found in 2/23 patients infected with CRF01_AE. |
| Variant ID. | 858 |
|---|---|
| Epitope Seq. | DLSHFLKEK |
| Variant Seq. | DLSfFLKEq |
| Mutations | H/F K/Q |
| Epitope Location | H4F K9Q |
| HXB2 Location | H89F K94Q |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | CRF01_AE |
| Note | Variant found in 1/23 patients infected with CRF01_AE. |
| Variant ID. | 859 |
|---|---|
| Epitope Seq. | DLSHFLKEK |
| Variant Seq. | DLSfFLrEq |
| Mutations | H/F K/R K/Q |
| Epitope Location | H4F K7R K9Q |
| HXB2 Location | H89F K92R K94Q |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | CRF01_AE |
| Note | Variant found in 1/23 patients infected with CRF01_AE. |
Lazaro2005 Estibaliz Lazaro, Ioannis Theodorou, Elisabeth Legrand, Patricia Recordon-Pinson, Sebastien Boucher, Corinne Capoulade, Thi Hoang Lan, Pham Van Hung, Patrice Debre, and Herve Fleury. Sequences of Clustered Epitopes in Gag and Nef Potentially Presented by Predominant Class I Human Leukocyte Antigen (HLA) Alleles A and B Expressed By Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Patients in Vietnam. AIDS Res. Hum. Retroviruses, 21(6):586-591, Jun 2005. PubMed ID: 15989466. Show all entries for this paper.