HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Nef(73-82) | Nef Epitope Map
View variants at this location |
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| Epitope |
QVPLRPMTYK
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Epitope Alignment | ||||||||||
| Variants |
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| Species (MHC/HLA) | human(A11, A3) | |||||||||||
Showing all: 3 variant(s).
| Variant ID. | 421 |
|---|---|
| Epitope Seq. | QVPLRPMTYK |
| Variant Seq. | QVPvRPMTYK |
| Mutations | L/V |
| Epitope Location | L4V |
| HXB2 Location | L76V |
| Mutation Type | OV: observed variant |
| Note | This variant was found in 1/5 subtype B infected patients. |
| Variant ID. | 422 |
|---|---|
| Epitope Seq. | QVPLRPMTYK |
| Variant Seq. | QVPmRPMTYK |
| Mutations | L/M |
| Epitope Location | L4M |
| HXB2 Location | L76M |
| Mutation Type | OV: observed variant |
| Note | This variant was found in 1/9 subtype CRF02_AG infected patients. |
| Variant ID. | 423 |
|---|---|
| Epitope Seq. | QVPLRPMTYK |
| Variant Seq. | QVPLRPMTfK |
| Mutations | Y/F |
| Epitope Location | Y9F |
| HXB2 Location | Y81F |
| Mutation Type | SF: susceptible form |
| Note | Mutation may impair T cell recognition, however, the variant was recognized in one patient as well as the wt. |
Inwoley2005 André Inwoley, Patricia Recordon-Pinson, Marion Dupuis, Jessintha Gaston, Mathieu Genête, Albert Minga, Franck Letourneur, François Rouet, Jeannine Choppin, Hervé Fleury, Jean-Gérard Guillet, Muriel Andrieu, and ANRS 1220 PRIMO-CI Study Group. Cross-Clade Conservation of HIV Type 1 Nef Immunodominant Regions Recognized by CD8+ T Cells of HIV Type 1 CRF02\_AG-Infected Ivorian (West Africa). AIDS Res. Hum. Retroviruses, 21(7):620-628, Jul 2005. PubMed ID: 16060833. Show all entries for this paper.