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Found 1 matching record:

Displaying record number 53728

HXB2 Location  Nef(73-82)   Nef Epitope Map
View variants at this location
Epitope QVPLRPMTYK   Epitope Alignment
Variants
QVPvRPMTYK   observed variant
QVPmRPMTYK   observed variant
QVPLRPMTfK   susceptible form
Species (MHC/HLA human(A11, A3)

Variant Details

Showing all: 3 variant(s).


Variant ID.  421
Epitope Seq.  QVPLRPMTYK
Variant Seq.  QVPvRPMTYK
Mutations L/V
Epitope Location L4V
HXB2 Location L76V
Mutation Type OV: observed variant
Note This variant was found in 1/5 subtype B infected patients.


Variant ID.  422
Epitope Seq.  QVPLRPMTYK
Variant Seq.  QVPmRPMTYK
Mutations L/M
Epitope Location L4M
HXB2 Location L76M
Mutation Type OV: observed variant
Note This variant was found in 1/9 subtype CRF02_AG infected patients.


Variant ID.  423
Epitope Seq.  QVPLRPMTYK
Variant Seq.  QVPLRPMTfK
Mutations Y/F
Epitope Location Y9F
HXB2 Location Y81F
Mutation Type SF: susceptible form
Note Mutation may impair T cell recognition, however, the variant was recognized in one patient as well as the wt.

References

Inwoley2005 André Inwoley, Patricia Recordon-Pinson, Marion Dupuis, Jessintha Gaston, Mathieu Genête, Albert Minga, Franck Letourneur, François Rouet, Jeannine Choppin, Hervé Fleury, Jean-Gérard Guillet, Muriel Andrieu, and ANRS 1220 PRIMO-CI Study Group. Cross-Clade Conservation of HIV Type 1 Nef Immunodominant Regions Recognized by CD8+ T Cells of HIV Type 1 CRF02\_AG-Infected Ivorian (West Africa). AIDS Res. Hum. Retroviruses, 21(7):620-628, Jul 2005. PubMed ID: 16060833. Show all entries for this paper.


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