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Found 1 matching record:

Displaying record number 53420

HXB2 Location  Gag(326-334)   Gag Epitope Map
View variants at this location
Epitope ANPDCKTIL   Epitope Alignment
Variants
sNPDCKTIL   observed variant
ANPDCKTIs   observed variant
Epitope Name ANP
Species (MHC/HLA human(B7)

Variant Details

Showing all: 2 variant(s).


Variant ID.  1354
Epitope Seq.  ANPDCKTIL
Variant Seq.  sNPDCKTIL
Mutations A/S
Epitope Location A1S
HXB2 Location A326S
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding
Note Only 1/18 viral clones contained this variant sequence at the first time point tested after infection.


Variant ID.  1355
Epitope Seq.  ANPDCKTIL
Variant Seq.  ANPDCKTIs
Mutations L/S
Epitope Location L9S
HXB2 Location L334S
Mutation Type OV: observed variant
Method CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding
Note Only 1/18 viral clones contained this variant sequence at the first time point tested after infection.

References

Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.


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