HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Nef(77-85) | Nef Epitope Map
View variants at this location |
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| Epitope |
RPMTYKGAL
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Epitope Alignment | ||||||||||||||||
| Variants |
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| Epitope Name | RPM | |||||||||||||||||
| Species (MHC/HLA) | human(B7) | |||||||||||||||||
Showing all: 5 variant(s).
| Variant ID. | 1394 |
|---|---|
| Epitope Seq. | RPMTYKGAL |
| Variant Seq. | RPMTYrGAL |
| Mutations | K/R |
| Epitope Location | K6R |
| HXB2 Location | K82R |
| Mutation Type | OV: observed variant |
| Method | CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding |
| Note | This variant was seen earlier and was proposed to be an escape. |
| Variant ID. | 1395 |
|---|---|
| Epitope Seq. | RPMTYKGAL |
| Variant Seq. | RPMTYKaAL |
| Mutations | G/A |
| Epitope Location | G7A |
| HXB2 Location | G83A |
| Mutation Type | OV: observed variant |
| Method | CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding |
| Note | This variant was seen earlier and was proposed to be an escape. |
| Variant ID. | 1396 |
|---|---|
| Epitope Seq. | RPMTYKGAL |
| Variant Seq. | RPMTYKGAv |
| Mutations | L/V |
| Epitope Location | L9V |
| HXB2 Location | L85V |
| Mutation Type | OV: observed variant |
| Method | CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding |
| Note | This variant was seen earlier and was proposed to be an escape. |
| Variant ID. | 1397 |
|---|---|
| Epitope Seq. | RPMTYKGAL |
| Variant Seq. | RPMsYKaAL |
| Mutations | T/S G/A |
| Epitope Location | T4S G7A |
| HXB2 Location | T80S G83A |
| Mutation Type | OV: observed variant |
| Method | CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding |
| Note | This was one of two most common forms of variants. |
| Variant ID. | 1398 |
|---|---|
| Epitope Seq. | RPMTYKGAL |
| Variant Seq. | RPMTfKGAL |
| Mutations | Y/F |
| Epitope Location | Y5F |
| HXB2 Location | Y81F |
| Mutation Type | OV: observed variant |
| Method | CD8 T-cell Elispot - IFNy, Sequence, Tetramer binding |
| Note | This was one of two most common forms of variants. |
Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.