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Found 1 matching record:

Displaying record number 52992

HXB2 Location  Nef(186-194)   Nef Epitope Map
View variants at this location
Epitope DSRLAFHHV   Epitope Alignment
Variants
DSlLAlrHm   observed variant
DSRLAvHHV   observed variant
Species (MHC/HLA human(B51)

Variant Details

Showing all: 2 variant(s).


Variant ID.  321
Epitope Seq.  DSRLAFHHV
Variant Seq.  DSlLAlrHm
Mutations R/L F/L H/R V/M
Epitope Location R3L F6L H7R V9M
HXB2 Location R188L F191L H192R V194M
Mutation Type OV: observed variant
Note The epitope varied over time but the mutations did not become fixed. The variant arose at early timepoints.


Variant ID.  322
Epitope Seq.  DSRLAFHHV
Variant Seq.  DSRLAvHHV
Mutations F/V
Epitope Location F6V
HXB2 Location F191V
Mutation Type OV: observed variant
Note The epitope varied over time but the mutations did not become fixed. The variant arose at intermediate timepoints.

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


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