HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 52988

HXB2 Location  Pol(415-426)   Pol Epitope Map
View variants at this location
Epitope LVGKLNWASQIY   Epitope Alignment
Variants
LVGKxNWASQIY   observed variant
Species (MHC/HLA human(B15)

Variant Details

Showing all: 1 variant(s).


Variant ID.  308
Epitope Seq.  LVGKLNWASQIY
Variant Seq.  LVGKxNWASQIY
Mutations L/X
Epitope Location L5X
HXB2 Location L419X
Mutation Type OV: observed variant
Note The epitope varied over time but the mutations did not become fixed. The variant arose at late timepoints.

References

Geels2003 Mark J. Geels, Marion Cornelissen, Hanneke Schuitemaker, Kiersten Anderson, David Kwa, Jolanda Maas, John T. Dekker, Elly Baan, Fokla Zorgdrager, Remco van den Burg, Martijn van Beelen, Vladimir V. Lukashov, Tong-Ming Fu, William A. Paxton, Lia van der Hoek, Sheri A. Dubey, John W. Shiver, and Jaap Goudsmit. Identification of Sequential Viral Escape Mutants Associated with Altered T-Cell Responses in a Human Immunodeficiency Virus Type 1-Infected Individual. J. Virol., 77(23):12430-12440, Dec 2003. PubMed ID: 14610167. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health