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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 52925

HXB2 Location  Gag(260-267)   Gag Epitope Map
View variants at this location
Epitope EIYKRWII   Epitope Alignment
Variants
dIYKRWII   susceptible form
Epitope Name E18
Species (MHC/HLA human(B8)

Variant Details

Showing all: 1 variant(s).


Variant ID.  182
Epitope Seq.  EIYKRWII
Variant Seq.  dIYKRWII
Mutations E/D
Epitope Location E1D
HXB2 Location E260D
Mutation Type SF: susceptible form
Note 3 subjects recognized this epitope with intermediate functional avidity. Autologous sequence revealed one substitution, Diyrkwil, in 1 of the 3; this version of the epitope also had intermediate functional avidity with the donor's cells.

References

Draenert2004b R. Draenert, C. L. Verrill, Y. Tang, T. M. Allen, A. G. Wurcel, M. Boczanowski, A. Lechner, A. Y. Kim, T. Suscovich, N. V. Brown, M. M. Addo, and B. D. Walker. Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(2):630-641, Jan 2004. PubMed ID: 14694094. Show all entries for this paper.


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