HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 52813

HXB2 Location  Vif(17-26)   Vif Epitope Map
View variants at this location
Epitope RIRTWKSLVK   Epitope Alignment
RIsTWKSLVK   susceptible form
Epitope Name A3-RK10 Vif
Species (MHC/HLA human(A3)

Variant Details

Showing all: 1 variant(s).

Variant ID.  48
Epitope Seq.  RIRTWKSLVK
Variant Seq.  RIsTWKSLVK
Mutations R/S
Epitope Location R3S
HXB2 Location R19S
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note Superinfection. The second infecting strain had the variant riStwkslvk. The initial CTL response persisted against both variants after the superinfection was established.


Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.

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