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Displaying record number 52813

HXB2 Location Vif(17-26) Vif Epitope Map
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Epitope

RIRTWKSLVK

Epitope Alignment

Variants

RIsTWKSLVK susceptible form

Epitope Name A3-RK10 Vif

Species (MHC/HLA) human(A3)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`48`
Epitope Seq.	`RIRTWKSLVK`
Variant Seq.	`RIsTWKSLVK`
Mutations	R/S
Epitope Location	R3S
HXB2 Location	R19S
Mutation Type	SF: susceptible form
Method	CD8 T-cell Elispot - IFNy
Note	Superinfection. The second infecting strain had the variant riStwkslvk. The initial CTL response persisted against both variants after the superinfection was established.

References

Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.