HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Pol(132-140)|| Pol Epitope Map
View variants at this location
Showing all: 2 variant(s).
|Mutation Type||DR: diminished response
E: escape documented in this paper
|Method||CD8 T-cell Elispot - IFNy, Chromium-release assay|
|Note||The variant was generally not recognized by wt CTL response, and when recognized, it was of low to moderate avidity. The emergence of the variant could not inhibit the wt CTL response, suggesting that the mutation did not affect recognition.|
|Mutation Type||OV: observed variant|
|Note||The emergence of the variant could not inhibit the wt CTL response, suggesting that the mutation did not affect recognition.|
Karlsson2003 Annika C Karlsson, Steven G Deeks, Jason D Barbour, Brandon D Heiken, Sophie R Younger, Rebecca Hoh, Meghan Lane, Matti Sällberg, Gabriel M Ortiz, James F Demarest, Teri Liegler, Robert M Grant, Jeffrey N Martin, and Douglas F Nixon. Dual Pressure from Antiretroviral Therapy and Cell-Mediated Immune Response on the Human Immunodeficiency Virus Type 1 Protease Gene. J. Virol., 77(12):6743-6752, Jun 2003. PubMed ID: 12767994. Show all entries for this paper.