HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||gp160(67-75)|| gp160 Epitope Map
View variants at this location
Showing all: 1 variant(s).
|Mutation Type||NSF: non-susceptible form
SF: susceptible form
|Method||CD8 T-cell Elispot - IFNy, Chromium-release assay, Flow cytometric T-cell cytokine assay|
|Note||This peptide was a good A2 binder, and induced CTL and CD8+ T-cell IFN gamma responses in mice. Responses were detected in 1/17 HIV+ HLA-A2 subjects. The variant nVwathacv was also immunogenic in transgenic mice, but was not recognized in the 17 people tested.|
Corbet2003 Sylvie Corbet, Henrik Vedel Nielsen, Lasse Vinner, Sanne Lauemoller, Dominic Therrien, Sheila Tang, Gitte Kronborg, Lars Mathiesen, Paul Chaplin, Søren Brunak, Søren Buus, and Anders Fomsgaard. Optimization and Immune Recognition of Multiple Novel Conserved HLA-A2, Human Immunodeficiency Virus Type 1-Specific CTL Epitopes. J. Gen. Virol., 84(Pt 9):2409-2421, Sep 2003. PubMed ID: 12917462. Show all entries for this paper.