HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 52105

HXB2 Location  gp160(199-207)   gp160 Epitope Map
View variants at this location
Epitope SVITQACPK   Epitope Alignment
SaITQACPK   observed variant
SVIkQACPK   susceptible form
Species (MHC/HLA human(A*11:01)

Variant Details

Showing all: 2 variant(s).

Variant ID.  298
Epitope Seq.  SVITQACPK
Variant Seq.  SaITQACPK
Mutations V/A
Epitope Location V2A
HXB2 Location V200A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A, C, D
Note Variant predominantly found in clades A, C and D.

Variant ID.  299
Epitope Seq.  SVITQACPK
Variant Seq.  SVIkQACPK
Mutations T/K
Epitope Location T4K
HXB2 Location T202K
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype CRF01_AE
Method Chromium-release assay
Note Variant predominantly found in clade E. There was low CTL activity in PBMC from clade E patients stimulated with this epitope variant.


Fukada2002 Katsuhiko Fukada, Hiroko Tomiyama, Chantapong Wasi, Tomoko Matsuda, Shigeru Kusagawa, Hironori Sato, Shinichi Oka, Yutaka Takebe, and Masafumi Takiguchi. Cytotoxic T-cell Recognition of HIV-1 Cross-Clade and Clade-Specific Epitopes in HIV-1-Infected Thai and Japanese Patients. AIDS, 16(5):701-711, 29 Mar 2002. PubMed ID: 11964526. Show all entries for this paper.

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