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Found 1 matching record:

Displaying record number 1684

HXB2 Location  Pol(330-338)   Pol Epitope Map
View variants at this location
Epitope HPDIVIYQY   Epitope Alignment
Variants
nPDIVIYQY   susceptible form
Species (MHC/HLA human(B35)

Variant Details

Showing all: 1 variant(s).


Variant ID.  673
Epitope Seq.  HPDIVIYQY
Variant Seq.  nPDIVIYQY
Mutations H/N
Epitope Location H1N
HXB2 Location H330N
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note This epitope and the variant were recognized by 1/4 HIV infected women and by 2/3 HIV-exposed, persistently seronegative women. Responses to the epitope and the variant were much higher before HIV-1 seroconversion of previous HEPS.

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


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