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HIV Molecular Immunology Database

Search the Epitope Variant and Escape Mutation Database

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Found 1 matching record:

Displaying record number 1680

HXB2 Location  Gag(293-302)   Gag Epitope Map
View variants at this location
Epitope FRDYVDRFYK   Epitope Alignment
Variants
FRDYVDRFfK   susceptible form
Species (MHC/HLA human(B18)

Variant Details

Showing all: 1 variant(s).


Variant ID.  679
Epitope Seq.  FRDYVDRFYK
Variant Seq.  FRDYVDRFfK
Mutations Y/F
Epitope Location Y9F
HXB2 Location Y301F
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note This epitope and the variant were recognized by 1/9 HIV infected women and by 3/4 HIV-exposed, persistently seronegative women.

References

Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: http://www.jci.org/cgi/content/full/107/10/1303. PubMed ID: 11375420. Show all entries for this paper.


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