HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 1660

HXB2 Location  gp160(586-593)   gp160 Epitope Map
View variants at this location
Epitope YLRDQQLL   Epitope Alignment
YLkDQQLL   susceptible form
Species (MHC/HLA human(A24)

Variant Details

Showing all: 1 variant(s).

Variant ID.  672
Epitope Seq.  YLRDQQLL
Variant Seq.  YLkDQQLL
Mutations R/K
Epitope Location R3K
HXB2 Location R588K
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note This epitope and the variant were recognized by 10/10 HIV infected women and by 3/4 HIV-exposed, persistently seronegative women.


Kaul2001a R. Kaul, T. Dong, F. A. Plummer, J. Kimani, T. Rostron, P. Kiama, E. Njagi, E. Irungu, B. Farah, J. Oyugi, R. Chakraborty, K. S. MacDonald, J. J. Bwayo, A. McMichael, and S. L. Rowland-Jones. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J. Clin. Invest., 107(10):1303-10, May 2001. URL: PubMed ID: 11375420. Show all entries for this paper.

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