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Displaying record number 1317

HXB2 Location  Rev(67-75)   Rev Epitope Map
View variants at this location
Epitope SAEPVPLQL   Epitope Alignment
Variants
SeEPVPLQL   escape documented in this paper
SAEhVPLQL   escape documented in this paper
SAEsVPLQL   escape documented in this paper
SvEPVPLQL   escape documented in this paper
SAEPVPfQL   escape documented in this paper
SlEPVPLQL   escape documented in this paper
Species (MHC/HLA human(B14)

Variant Details

Showing all: 6 variant(s).


Variant ID.  1604
Epitope Seq.  SAEPVPLQL
Variant Seq.  SeEPVPLQL
Mutations A/E
Epitope Location A2E
HXB2 Location A68E
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.


Variant ID.  1605
Epitope Seq.  SAEPVPLQL
Variant Seq.  SAEhVPLQL
Mutations P/H
Epitope Location P4H
HXB2 Location P70H
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.


Variant ID.  1606
Epitope Seq.  SAEPVPLQL
Variant Seq.  SAEsVPLQL
Mutations P/S
Epitope Location P4S
HXB2 Location P70S
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.


Variant ID.  1607
Epitope Seq.  SAEPVPLQL
Variant Seq.  SvEPVPLQL
Mutations A/V
Epitope Location A2V
HXB2 Location A68V
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.


Variant ID.  1608
Epitope Seq.  SAEPVPLQL
Variant Seq.  SAEPVPfQL
Mutations L/F
Epitope Location L7F
HXB2 Location L73F
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.


Variant ID.  1609
Epitope Seq.  SAEPVPLQL
Variant Seq.  SlEPVPLQL
Mutations A/L
Epitope Location A2L
HXB2 Location A68L
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note Macrophage-tropic HIV-1 clone escaped more efficiently from specific cytotoxic T-lymphocyte (CTL) pressure than its non-macrophage-tropic counterpart. This variant was escape in mice as demonstrated by Cr release assay.

References

Schutten2001 M. Schutten, C. A. van Baalen, C. Guillon, R. C. Huisman, P. H. Boers, K. Sintnicolaas, R. A. Gruters, and A. D. Osterhaus. Macrophage tropism of human immunodeficiency virus type 1 facilitates in vivo escape from cytotoxic T-lymphocyte pressure. J. Virol., 75(6):2706-9, Mar 2001. URL: http://jvi.asm.org/cgi/content/full/75/6/2706. PubMed ID: 11222694. Show all entries for this paper.


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