HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 1056

HXB2 Location  Nef(128-137)   Nef Epitope Map
View variants at this location
Epitope TPGPGVRYPL   Epitope Alignment
TPGPGiRYPL   observed variant
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).

Variant ID.  1551
Epitope Seq.  TPGPGVRYPL
Variant Seq.  TPGPGiRYPL
Mutations V/I
Epitope Location V6I
HXB2 Location V133I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A, D
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A and D clade form, TPGPGiRYPL.


Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.

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