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Found 24 matching records:

Displaying record number 54629

HXB2 Location  Gag(17-34)   Gag Epitope Map
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Epitope EKIRLRPGGKKKYRLKHL   Epitope Alignment
Variants
EKIRLRPGGKKhYmLKHL   subtype-specific susceptible form
Epitope Name GAG-03
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1957
Epitope Seq.  EKIRLRPGGKKKYRLKHL
Variant Seq.  EKIRLRPGGKKhYmLKHL
Mutations K/H R/M
Epitope Location K12H R14M
HXB2 Location K28H R30M
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54628

HXB2 Location  Gag(126-143)   Gag Epitope Map
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Epitope SQVSQNYPIVQNLQGQMV   Epitope Alignment
Variants
-kVSQNYPIVQNLQGQMV   subtype-specific susceptible form
Epitope Name GAG-18
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2269
Epitope Seq.  SQVSQNYPIVQNLQGQMV
Variant Seq.  -kVSQNYPIVQNLQGQMV
Mutations S/- Q/K
Epitope Location S1- Q2K
HXB2 Location S126- Q127K
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54631

HXB2 Location  Gag(163-179)   Gag Epitope Map
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Epitope AFSPEVIPMFSALSEGA   Epitope Alignment
Variants
AFSPEVIPMFtALSEGA   subtype-specific susceptible form
Epitope Name GAG-23
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1956
Epitope Seq.  AFSPEVIPMFSALSEGA
Variant Seq.  AFSPEVIPMFtALSEGA
Mutations S/T
Epitope Location S11T
HXB2 Location S173T
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.9%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54630

HXB2 Location  Gag(170-187)   Gag Epitope Map
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Epitope PMFSALSEGATPQDLNTM   Epitope Alignment
Variants
PMFtALSEGATPQDLNTM   subtype-specific susceptible form
Epitope Name GAG-24
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1958
Epitope Seq.  PMFSALSEGATPQDLNTM
Variant Seq.  PMFtALSEGATPQDLNTM
Mutations S/T
Epitope Location S4T
HXB2 Location S173T
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54632

HXB2 Location  Gag(193-210)   Gag Epitope Map
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Epitope GHQAAMQMLKETINEEAA   Epitope Alignment
Variants
GHQAAMQMLKdTINEEAA   subtype-specific susceptible form
Epitope Name GAG-27
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1959
Epitope Seq.  GHQAAMQMLKETINEEAA
Variant Seq.  GHQAAMQMLKdTINEEAA
Mutations E/D
Epitope Location E11D
HXB2 Location E203D
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54633

HXB2 Location  Gag(201-218)   Gag Epitope Map
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Epitope LKETINEEAAEWDRLHPV   Epitope Alignment
Variants
LKdTINEEAAEWDRLHPV   subtype-specific susceptible form
Epitope Name GAG-28
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1960
Epitope Seq.  LKETINEEAAEWDRLHPV
Variant Seq.  LKdTINEEAAEWDRLHPV
Mutations E/D
Epitope Location E3D
HXB2 Location E203D
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54634

HXB2 Location  Gag(288-305)   Gag Epitope Map
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Epitope GPKEPFRDYVDRFYKTLR   Epitope Alignment
Variants
GPKEPFRDYVDRFfKTLR   subtype-specific susceptible form
Epitope Name GAG-40
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1961
Epitope Seq.  GPKEPFRDYVDRFYKTLR
Variant Seq.  GPKEPFRDYVDRFfKTLR
Mutations Y/F
Epitope Location Y14F
HXB2 Location Y301F
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54635

HXB2 Location  Gag(296-313)   Gag Epitope Map
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Epitope YVDRFYKTLRAEQASQEV   Epitope Alignment
Variants
YVDRFfKTLRAEQAtQdV   subtype-specific susceptible form
Epitope Name GAG-41
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1962
Epitope Seq.  YVDRFYKTLRAEQASQEV
Variant Seq.  YVDRFfKTLRAEQAtQdV
Mutations S/T E/D Y/F
Epitope Location S15T E17D Y6F
HXB2 Location S310T E312D Y301F
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54636

HXB2 Location  Gag(304-321)   Gag Epitope Map
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Epitope LRAEQASQEVKNWMTETL   Epitope Alignment
Variants
LRAEQAtQdVKNWMTdTL   subtype-specific susceptible form
Epitope Name GAG-42
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1963
Epitope Seq.  LRAEQASQEVKNWMTETL
Variant Seq.  LRAEQAtQdVKNWMTdTL
Mutations E/D S/T E/D
Epitope Location E16D S7T E9D
HXB2 Location E319D S310T E312D
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54637

HXB2 Location  Gag(340-358)   Gag Epitope Map
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Epitope AATLEEMMTACQGVGGPSH   Epitope Alignment
Variants
gAsLEEMMTACQGVGGPSH   subtype-specific susceptible form
Epitope Name GAG-47
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1964
Epitope Seq.  AATLEEMMTACQGVGGPSH
Variant Seq.  gAsLEEMMTACQGVGGPSH
Mutations A/G T/S
Epitope Location A1G T3S
HXB2 Location A340G T342S
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (10.5%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54639

HXB2 Location  Gag(474-490)   Gag Epitope Map
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Epitope QKQEPIDKELYPLASLK   Epitope Alignment
Variants
pKQEPkDrE--PLtSLK   subtype-specific susceptible form
Epitope Name GAG-65
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1965
Epitope Seq.  QKQEPIDKELYPLASLK
Variant Seq.  pKQEPkDrE--PLtSLK
Mutations Q/P L/- Y/- A/T I/K K/R
Epitope Location Q1P L10- Y11- A14T I6K K8R
HXB2 Location Q474P L483- Y484- A487T I479K K481R
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 6 amino acids (35.3%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54641

HXB2 Location  Gag(481-498)   Gag Epitope Map
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Epitope KELYPLASLKSLFGNDPS   Epitope Alignment
Variants
rE--PL-SLKSLFGsDPl   subtype-specific susceptible form
Epitope Name GAG-66
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1966
Epitope Seq.  KELYPLASLKSLFGNDPS
Variant Seq.  rE--PL-SLKSLFGsDPl
Mutations K/R N/S S/L L/- Y/- A/-
Epitope Location K1R N15S S18L L3- Y4- A7-
HXB2 Location K481R N495S S498L L483- Y484- A487-
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 5 amino acids (33.3%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54648

HXB2 Location  Pol(528-545)   Pol Epitope Map
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Epitope QKIATESIVIWGKTPKFK   Epitope Alignment
Variants
QKIAmESIVIWGKTPKFr   subtype-specific susceptible form
Epitope Name POL-72
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1967
Epitope Seq.  QKIATESIVIWGKTPKFK
Variant Seq.  QKIAmESIVIWGKTPKFr
Mutations K/R T/M
Epitope Location K18R T5M
HXB2 Location K545R T532M
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54653

HXB2 Location  Vif(64-81)   Vif Epitope Map
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Epitope LVITTYWGLHTGERDWHL   Epitope Alignment
Variants
LVIkTYWGLqTGERDWHL   subtype-specific susceptible form
Epitope Name VIF-09
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2270
Epitope Seq.  LVITTYWGLHTGERDWHL
Variant Seq.  LVIkTYWGLqTGERDWHL
Mutations H/Q T/K
Epitope Location H10Q T4K
HXB2 Location H73Q T67K
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54654

HXB2 Location  Vif(93-110)   Vif Epitope Map
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Epitope RYSTQVDPGLADQLIHLY   Epitope Alignment
Variants
RYSTQVePGLADQLIHmh   subtype-specific susceptible form
Epitope Name VIF-13
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1969
Epitope Seq.  RYSTQVDPGLADQLIHLY
Variant Seq.  RYSTQVePGLADQLIHmh
Mutations L/M Y/H D/E
Epitope Location L17M Y18H D7E
HXB2 Location L109M Y110H D99E
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54650

HXB2 Location  gp160(30-46)   gp160 Epitope Map
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Epitope AAENLWVTVYYGVPVWK   Epitope Alignment
Variants
vggNLWVTVYYGVPVWK   subtype-specific susceptible form
Epitope Name ENV-05
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1970
Epitope Seq.  AAENLWVTVYYGVPVWK
Variant Seq.  vggNLWVTVYYGVPVWK
Mutations A/V A/G E/G
Epitope Location A1V A2G E3G
HXB2 Location A30V A31G E32G
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (17.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54651

HXB2 Location  gp160(37-53)   gp160 Epitope Map
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Epitope TVYYGVPVWKEATTTLF   Epitope Alignment
Variants
TVYYGVPVWKEAkTTLF   subtype-specific susceptible form
Epitope Name ENV-06
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1971
Epitope Seq.  TVYYGVPVWKEATTTLF
Variant Seq.  TVYYGVPVWKEAkTTLF
Mutations T/K
Epitope Location T13K
HXB2 Location T49K
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.9%) and was recognized.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54640

HXB2 Location  Nef(65-82)   Nef Epitope Map
View variants at this location
Epitope EVGFPVRPQVPLRPMTYK   Epitope Alignment
Variants
EVGFPVRPQVPLRPMTfK   subtype-specific susceptible form
Epitope Name NEF-10
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1972
Epitope Seq.  EVGFPVRPQVPLRPMTYK
Variant Seq.  EVGFPVRPQVPLRPMTfK
Mutations Y/F
Epitope Location Y17F
HXB2 Location Y81F
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54642

HXB2 Location  Nef(81-97)   Nef Epitope Map
View variants at this location
Epitope YKGALDLSHFLKEKGGL   Epitope Alignment
Variants
fKGAfDLSfFLKEKGGL   subtype-specific susceptible form
Epitope Name NEF-12
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1973
Epitope Seq.  YKGALDLSHFLKEKGGL
Variant Seq.  fKGAfDLSfFLKEKGGL
Mutations Y/F L/F H/F
Epitope Location Y1F L5F H9F
HXB2 Location Y81F L85F H89F
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (17.6%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54643

HXB2 Location  Nef(88-105)   Nef Epitope Map
View variants at this location
Epitope SHFLKEKGGLEGLIYSQK   Epitope Alignment
Variants
SfFLKEKGGLEGLIYSkK   subtype-specific susceptible form
Epitope Name NEF-13
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1974
Epitope Seq.  SHFLKEKGGLEGLIYSQK
Variant Seq.  SfFLKEKGGLEGLIYSkK
Mutations Q/K H/F
Epitope Location Q17K H2F
HXB2 Location Q104K H89F
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54644

HXB2 Location  Nef(96-113)   Nef Epitope Map
View variants at this location
Epitope GLEGLIYSQKRQDILDLW   Epitope Alignment
Variants
GLEGLIYSkKRQeILDLW   subtype-specific susceptible form
Epitope Name NEF-14
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1975
Epitope Seq.  GLEGLIYSQKRQDILDLW
Variant Seq.  GLEGLIYSkKRQeILDLW
Mutations D/E Q/K
Epitope Location D13E Q9K
HXB2 Location D108E Q104K
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54645

HXB2 Location  Nef(104-121)   Nef Epitope Map
View variants at this location
Epitope QKRQDILDLWVYHTQGYF   Epitope Alignment
Variants
kKRQeILDLWVYHTQGYF   subtype-specific susceptible form
Epitope Name NEF-15
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1976
Epitope Seq.  QKRQDILDLWVYHTQGYF
Variant Seq.  kKRQeILDLWVYHTQGYF
Mutations Q/K D/E
Epitope Location Q1K D5E
HXB2 Location Q104K D108E
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54646

HXB2 Location  Nef(118-135)   Nef Epitope Map
View variants at this location
Epitope QGYFPDWQNYTPGPGRF   Epitope Alignment
Variants
QGYFPDWQNYTPGPvRy   subtype-specific susceptible form
Epitope Name NEF-17
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1977
Epitope Seq.  QGYFPDWQNYTPGPGRF
Variant Seq.  QGYFPDWQNYTPGPvRy
Mutations G/V F/Y
Epitope Location G15V F17Y
HXB2 Location G132V F134Y
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


Displaying record number 54647

HXB2 Location  Nef(125-143)   Nef Epitope Map
View variants at this location
Epitope QNYTPGPGRFPLTFGWCF   Epitope Alignment
Variants
QNYTPGPGvRyPLTFGWCF   subtype-specific susceptible form
Epitope Name NEF-18
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1978
Epitope Seq.  QNYTPGPGRFPLTFGWCF
Variant Seq.  QNYTPGPGvRyPLTFGWCF
Mutations F/R P/Y L/P T/L F/T G/F W/G C/W F/C R/V
Epitope Location F10R P11Y L12P T13L F14T G15F W16G C17W F18C R9V
HXB2 Location F134R P135Y L136P T137L F138T G139F W140G C141W F142C R133V
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (10.5%) and both were recognized by subtype-B-infected subjects.

References

Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.


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