HIV molecular immunology database
Found 24 matching records:
HXB2 Location | Gag(17-34) | Gag Epitope Map
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Epitope |
EKIRLRPGGKKKYRLKHL
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Epitope Name | GAG-03 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1957 |
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Epitope Seq. | EKIRLRPGGKKKYRLKHL |
Variant Seq. | EKIRLRPGGKKhYmLKHL |
Mutations | K/H R/M |
Epitope Location | K12H R14M |
HXB2 Location | K28H R30M |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(126-143) | Gag Epitope Map
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Epitope |
SQVSQNYPIVQNLQGQMV
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Epitope Alignment | ||||
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Epitope Name | GAG-18 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 2269 |
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Epitope Seq. | SQVSQNYPIVQNLQGQMV |
Variant Seq. | -kVSQNYPIVQNLQGQMV |
Mutations | S/- Q/K |
Epitope Location | S1- Q2K |
HXB2 Location | S126- Q127K |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(163-179) | Gag Epitope Map
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Epitope |
AFSPEVIPMFSALSEGA
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Epitope Alignment | ||||
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Epitope Name | GAG-23 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1956 |
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Epitope Seq. | AFSPEVIPMFSALSEGA |
Variant Seq. | AFSPEVIPMFtALSEGA |
Mutations | S/T |
Epitope Location | S11T |
HXB2 Location | S173T |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.9%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(170-187) | Gag Epitope Map
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Epitope |
PMFSALSEGATPQDLNTM
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Epitope Name | GAG-24 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1958 |
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Epitope Seq. | PMFSALSEGATPQDLNTM |
Variant Seq. | PMFtALSEGATPQDLNTM |
Mutations | S/T |
Epitope Location | S4T |
HXB2 Location | S173T |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(193-210) | Gag Epitope Map
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Epitope |
GHQAAMQMLKETINEEAA
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Epitope Alignment | ||||
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Epitope Name | GAG-27 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1959 |
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Epitope Seq. | GHQAAMQMLKETINEEAA |
Variant Seq. | GHQAAMQMLKdTINEEAA |
Mutations | E/D |
Epitope Location | E11D |
HXB2 Location | E203D |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(201-218) | Gag Epitope Map
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Epitope |
LKETINEEAAEWDRLHPV
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Epitope Alignment | ||||
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Epitope Name | GAG-28 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1960 |
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Epitope Seq. | LKETINEEAAEWDRLHPV |
Variant Seq. | LKdTINEEAAEWDRLHPV |
Mutations | E/D |
Epitope Location | E3D |
HXB2 Location | E203D |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(288-305) | Gag Epitope Map
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Epitope |
GPKEPFRDYVDRFYKTLR
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Epitope Alignment | ||||
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Epitope Name | GAG-40 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1961 |
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Epitope Seq. | GPKEPFRDYVDRFYKTLR |
Variant Seq. | GPKEPFRDYVDRFfKTLR |
Mutations | Y/F |
Epitope Location | Y14F |
HXB2 Location | Y301F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(296-313) | Gag Epitope Map
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Epitope |
YVDRFYKTLRAEQASQEV
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Epitope Alignment | ||||
Variants |
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Epitope Name | GAG-41 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1962 |
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Epitope Seq. | YVDRFYKTLRAEQASQEV |
Variant Seq. | YVDRFfKTLRAEQAtQdV |
Mutations | S/T E/D Y/F |
Epitope Location | S15T E17D Y6F |
HXB2 Location | S310T E312D Y301F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(304-321) | Gag Epitope Map
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Epitope |
LRAEQASQEVKNWMTETL
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Epitope Alignment | ||||
Variants |
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Epitope Name | GAG-42 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1963 |
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Epitope Seq. | LRAEQASQEVKNWMTETL |
Variant Seq. | LRAEQAtQdVKNWMTdTL |
Mutations | E/D S/T E/D |
Epitope Location | E16D S7T E9D |
HXB2 Location | E319D S310T E312D |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(340-358) | Gag Epitope Map
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Epitope |
AATLEEMMTACQGVGGPSH
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Epitope Alignment | ||||
Variants |
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Epitope Name | GAG-47 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1964 |
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Epitope Seq. | AATLEEMMTACQGVGGPSH |
Variant Seq. | gAsLEEMMTACQGVGGPSH |
Mutations | A/G T/S |
Epitope Location | A1G T3S |
HXB2 Location | A340G T342S |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (10.5%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(474-490) | Gag Epitope Map
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Epitope |
QKQEPIDKELYPLASLK
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Epitope Alignment | ||||
Variants |
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Epitope Name | GAG-65 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1965 |
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Epitope Seq. | QKQEPIDKELYPLASLK |
Variant Seq. | pKQEPkDrE--PLtSLK |
Mutations | Q/P L/- Y/- A/T I/K K/R |
Epitope Location | Q1P L10- Y11- A14T I6K K8R |
HXB2 Location | Q474P L483- Y484- A487T I479K K481R |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 6 amino acids (35.3%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Gag(481-498) | Gag Epitope Map
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Epitope |
KELYPLASLKSLFGNDPS
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Epitope Alignment | ||||
Variants |
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Epitope Name | GAG-66 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1966 |
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Epitope Seq. | KELYPLASLKSLFGNDPS |
Variant Seq. | rE--PL-SLKSLFGsDPl |
Mutations | K/R N/S S/L L/- Y/- A/- |
Epitope Location | K1R N15S S18L L3- Y4- A7- |
HXB2 Location | K481R N495S S498L L483- Y484- A487- |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 5 amino acids (33.3%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Pol(528-545) | Pol Epitope Map
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Epitope |
QKIATESIVIWGKTPKFK
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Epitope Alignment | ||||
Variants |
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Epitope Name | POL-72 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1967 |
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Epitope Seq. | QKIATESIVIWGKTPKFK |
Variant Seq. | QKIAmESIVIWGKTPKFr |
Mutations | K/R T/M |
Epitope Location | K18R T5M |
HXB2 Location | K545R T532M |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Vif(64-81) | Vif Epitope Map
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Epitope |
LVITTYWGLHTGERDWHL
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Epitope Alignment | ||||
Variants |
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Epitope Name | VIF-09 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 2270 |
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Epitope Seq. | LVITTYWGLHTGERDWHL |
Variant Seq. | LVIkTYWGLqTGERDWHL |
Mutations | H/Q T/K |
Epitope Location | H10Q T4K |
HXB2 Location | H73Q T67K |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Vif(93-110) | Vif Epitope Map
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Epitope |
RYSTQVDPGLADQLIHLY
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Epitope Alignment | ||||
Variants |
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Epitope Name | VIF-13 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1969 |
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Epitope Seq. | RYSTQVDPGLADQLIHLY |
Variant Seq. | RYSTQVePGLADQLIHmh |
Mutations | L/M Y/H D/E |
Epitope Location | L17M Y18H D7E |
HXB2 Location | L109M Y110H D99E |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (16.7%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | gp160(30-46) | gp160 Epitope Map
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Epitope |
AAENLWVTVYYGVPVWK
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Epitope Alignment | ||||
Variants |
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Epitope Name | ENV-05 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1970 |
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Epitope Seq. | AAENLWVTVYYGVPVWK |
Variant Seq. | vggNLWVTVYYGVPVWK |
Mutations | A/V A/G E/G |
Epitope Location | A1V A2G E3G |
HXB2 Location | A30V A31G E32G |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (17.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | gp160(37-53) | gp160 Epitope Map
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Epitope |
TVYYGVPVWKEATTTLF
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Epitope Alignment | ||||
Variants |
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Epitope Name | ENV-06 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1971 |
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Epitope Seq. | TVYYGVPVWKEATTTLF |
Variant Seq. | TVYYGVPVWKEAkTTLF |
Mutations | T/K |
Epitope Location | T13K |
HXB2 Location | T49K |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.9%) and was recognized. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(65-82) | Nef Epitope Map
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Epitope |
EVGFPVRPQVPLRPMTYK
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-10 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1972 |
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Epitope Seq. | EVGFPVRPQVPLRPMTYK |
Variant Seq. | EVGFPVRPQVPLRPMTfK |
Mutations | Y/F |
Epitope Location | Y17F |
HXB2 Location | Y81F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 1 amino acid (5.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(81-97) | Nef Epitope Map
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Epitope |
YKGALDLSHFLKEKGGL
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-12 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1973 |
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Epitope Seq. | YKGALDLSHFLKEKGGL |
Variant Seq. | fKGAfDLSfFLKEKGGL |
Mutations | Y/F L/F H/F |
Epitope Location | Y1F L5F H9F |
HXB2 Location | Y81F L85F H89F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 3 amino acids (17.6%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(88-105) | Nef Epitope Map
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Epitope |
SHFLKEKGGLEGLIYSQK
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-13 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1974 |
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Epitope Seq. | SHFLKEKGGLEGLIYSQK |
Variant Seq. | SfFLKEKGGLEGLIYSkK |
Mutations | Q/K H/F |
Epitope Location | Q17K H2F |
HXB2 Location | Q104K H89F |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(96-113) | Nef Epitope Map
View variants at this location |
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Epitope |
GLEGLIYSQKRQDILDLW
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-14 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1975 |
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Epitope Seq. | GLEGLIYSQKRQDILDLW |
Variant Seq. | GLEGLIYSkKRQeILDLW |
Mutations | D/E Q/K |
Epitope Location | D13E Q9K |
HXB2 Location | D108E Q104K |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(104-121) | Nef Epitope Map
View variants at this location |
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Epitope |
QKRQDILDLWVYHTQGYF
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-15 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1976 |
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Epitope Seq. | QKRQDILDLWVYHTQGYF |
Variant Seq. | kKRQeILDLWVYHTQGYF |
Mutations | Q/K D/E |
Epitope Location | Q1K D5E |
HXB2 Location | Q104K D108E |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(118-135) | Nef Epitope Map
View variants at this location |
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Epitope |
QGYFPDWQNYTPGPGRF
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-17 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1977 |
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Epitope Seq. | QGYFPDWQNYTPGPGRF |
Variant Seq. | QGYFPDWQNYTPGPvRy |
Mutations | G/V F/Y |
Epitope Location | G15V F17Y |
HXB2 Location | G132V F134Y |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.
HXB2 Location | Nef(125-143) | Nef Epitope Map
View variants at this location |
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Epitope |
QNYTPGPGRFPLTFGWCF
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Epitope Alignment | ||||
Variants |
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Epitope Name | NEF-18 | |||||
Species (MHC/HLA) | human |
Showing all: 1 variant(s).
Variant ID. | 1978 |
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Epitope Seq. | QNYTPGPGRFPLTFGWCF |
Variant Seq. | QNYTPGPGvRyPLTFGWCF |
Mutations | F/R P/Y L/P T/L F/T G/F W/G C/W F/C R/V |
Epitope Location | F10R P11Y L12P T13L F14T G15F W16G C17W F18C R9V |
HXB2 Location | F134R P135Y L136P T137L F138T G139F W140G C141W F142C R133V |
Mutation Type | SSF: subtype-specific susceptible form |
Epitope Subtype | B |
Variant Subtype | C |
Method | CD8 T-cell Elispot - IFNy, Sequence |
Note | This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (10.5%) and both were recognized by subtype-B-infected subjects. |
Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.