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Found 50 matching records:

Displaying record number 56027

HXB2 Location  Gag(11-19)   Gag Epitope Map
View variants at this location
Epitope GQLDRWEKI   Epitope Alignment
Variants
GeLDRWEKI   observed variant
Epitope Name GI9(p17)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1903
Epitope Seq.  GQLDRWEKI
Variant Seq.  GeLDRWEKI
Mutations Q/E
Epitope Location Q2E
HXB2 Location Q12E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B40 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55928

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope KYRLKHLVW   Epitope Alignment
Variants
KYkLKHLVW   observed variant
Epitope Name KW9(p17)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1904
Epitope Seq.  KYRLKHLVW
Variant Seq.  KYkLKHLVW
Mutations R/K
Epitope Location R3K
HXB2 Location R30K
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A24 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55946

HXB2 Location  Gag(76-86)   Gag Epitope Map
View variants at this location
Epitope RSLFNTVATLY   Epitope Alignment
Variants
RSLyNTVATLY   observed variant
Epitope Name RY11(p17)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1905
Epitope Seq.  RSLFNTVATLY
Variant Seq.  RSLyNTVATLY
Mutations F/Y
Epitope Location F4Y
HXB2 Location F79Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55939

HXB2 Location  Gag(78-86)   Gag Epitope Map
View variants at this location
Epitope LFNTVATLY   Epitope Alignment
Variants
LyNTVATLY   observed variant
Epitope Name LY9(p17)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1906
Epitope Seq.  LFNTVATLY
Variant Seq.  LyNTVATLY
Mutations F/Y
Epitope Location F2Y
HXB2 Location F79Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A29 restricted and possibly HLA-B44 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56010

HXB2 Location  Gag(124-132)   Gag Epitope Map
View variants at this location
Epitope NSSQVSQNY   Epitope Alignment
Variants
NSSkVSQNY   observed variant
Epitope Name NY9(p17)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1907
Epitope Seq.  NSSQVSQNY
Variant Seq.  NSSkVSQNY
Mutations Q/K
Epitope Location Q4K
HXB2 Location Q127K
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B35 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55992

HXB2 Location  Gag(144-152)   Gag Epitope Map
View variants at this location
Epitope HQPISPRTL   Epitope Alignment
Variants
HQaISPRTL   observed variant
Epitope Name HL9(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1908
Epitope Seq.  HQPISPRTL
Variant Seq.  HQaISPRTL
Mutations P/A
Epitope Location P3A
HXB2 Location P146A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope. This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B15 restricted.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56011

HXB2 Location  Gag(254-262)   Gag Epitope Map
View variants at this location
Epitope PPIPVGEIY   Epitope Alignment
Variants
PPIPVGdIY   observed variant
NPVPVGNIY   observed variant
Epitope Name PY9(p24)
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  1909
Epitope Seq.  PPIPVGEIY
Variant Seq.  PPIPVGdIY
Mutations E/D
Epitope Location E7D
HXB2 Location E260D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B35 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.


Variant ID.  1910
Epitope Seq.  PPIPVGEIY
Variant Seq.  NPVPVGNIY
Mutations P/N I/V E/N
Epitope Location P1N I3V E7N
HXB2 Location P254N I256V E260N
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at 3 residues. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55936

HXB2 Location  Gag(294-304)   Gag Epitope Map
View variants at this location
Epitope RDYVDRFYKTL   Epitope Alignment
Variants
RDYVDRFfKTL   observed variant
Epitope Name RL11(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1911
Epitope Seq.  RDYVDRFYKTL
Variant Seq.  RDYVDRFfKTL
Mutations Y/F
Epitope Location Y8F
HXB2 Location Y301F
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A24, -A26 and -B35 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55899

HXB2 Location  Gag(296-304)   Gag Epitope Map
View variants at this location
Epitope YVDRFYKTL   Epitope Alignment
Variants
YVDRFfKTL   observed variant
Epitope Name YL9(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1912
Epitope Seq.  YVDRFYKTL
Variant Seq.  YVDRFfKTL
Mutations Y/F
Epitope Location Y6F
HXB2 Location Y301F
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A2 and -B15 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56042

HXB2 Location  Gag(306-316)   Gag Epitope Map
View variants at this location
Epitope AEQASQEVKNW   Epitope Alignment
Variants
AEQASQdVKNW   observed variant
Epitope Name AW11(p24)
Species (MHC/HLA human(B44)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1913
Epitope Seq.  AEQASQEVKNW
Variant Seq.  AEQASQdVKNW
Mutations E/D
Epitope Location E7D
HXB2 Location E312D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55919

HXB2 Location  Gag(349-359)   Gag Epitope Map
View variants at this location
Epitope ACQGVGGPSHK   Epitope Alignment
Variants
ACQGVGGPgHK   observed variant
Epitope Name AK11(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1914
Epitope Seq.  ACQGVGGPSHK
Variant Seq.  ACQGVGGPgHK
Mutations S/G
Epitope Location S9G
HXB2 Location S357G
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope. This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A11 restricted.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55918

HXB2 Location  Gag(352-359)   Gag Epitope Map
View variants at this location
Epitope GVGGPSHK   Epitope Alignment
Variants
GVGGPgHK   observed variant
Epitope Name GK8(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1915
Epitope Seq.  GVGGPSHK
Variant Seq.  GVGGPgHK
Mutations S/G
Epitope Location S6G
HXB2 Location S357G
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A11 restricted. No recognition was seen by CTL from HLA-A3 carriers.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55972

HXB2 Location  Gag(355-363)   Gag Epitope Map
View variants at this location
Epitope GPSHKARVL   Epitope Alignment
Variants
GPgHKARVL   observed variant
Epitope Name GL9(p24)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1916
Epitope Seq.  GPSHKARVL
Variant Seq.  GPgHKARVL
Mutations S/G
Epitope Location S3G
HXB2 Location S357G
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope. This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56034

HXB2 Location  Gag(481-489)   Gag Epitope Map
View variants at this location
Epitope KELYPLTSL   Epitope Alignment
Variants
KELYPLaSL   observed variant
Epitope Name KL9(p2p7p1p6)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1917
Epitope Seq.  KELYPLTSL
Variant Seq.  KELYPLaSL
Mutations T/A
Epitope Location T7A
HXB2 Location T487A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B40 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55968

HXB2 Location  Pol(86-94)   Pol Epitope Map
View variants at this location
Epitope DTVLEDMNL   Epitope Alignment
Variants
DTVLEewNL   observed variant
Epitope Name DL9(Protease)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1918
Epitope Seq.  DTVLEDMNL
Variant Seq.  DTVLEewNL
Mutations D/E M/W
Epitope Location D6E M7W
HXB2 Location D91E M92W
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at two positions. It is predicted to be HLA-A68 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56043

HXB2 Location  Pol(90-98)   Pol Epitope Map
View variants at this location
Epitope EDMNLPGRW   Epitope Alignment
Variants
EeMNLPGRW   observed variant
Epitope Name EW9(Protease)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1919
Epitope Seq.  EDMNLPGRW
Variant Seq.  EeMNLPGRW
Mutations D/E
Epitope Location D2E
HXB2 Location D91E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope. This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B44 restricted.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55989

HXB2 Location  Pol(113-122)   Pol Epitope Map
View variants at this location
Epitope RQYDQIPIEI   Epitope Alignment
Variants
RQYDQIlIEI   observed variant
Epitope Name RI10(Protease)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1920
Epitope Seq.  RQYDQIPIEI
Variant Seq.  RQYDQIlIEI
Mutations P/L
Epitope Location P7L
HXB2 Location P119L
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B13 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56000

HXB2 Location  Pol(124-132)   Pol Epitope Map
View variants at this location
Epitope GKKAIGTVL   Epitope Alignment
Variants
GhKAIGTVL   observed variant
Epitope Name GL9(Protease)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1921
Epitope Seq.  GKKAIGTVL
Variant Seq.  GhKAIGTVL
Mutations K/H
Epitope Location K2H
HXB2 Location K125H
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B15 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56015

HXB2 Location  Pol(273-282)   Pol Epitope Map
View variants at this location
Epitope VPLDKDFRKY   Epitope Alignment
Variants
VPLDeDFRKY   observed variant
Epitope Name VY10(RT)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1922
Epitope Seq.  VPLDKDFRKY
Variant Seq.  VPLDeDFRKY
Mutations K/E
Epitope Location K5E
HXB2 Location K277E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B35 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56458

HXB2 Location  Pol(313-321)   Pol Epitope Map
View variants at this location
Epitope AIFQCSMTK   Epitope Alignment
Variants
AIFQsSMTK   observed variant
Epitope Name AK9(RT)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1923
Epitope Seq.  AIFQCSMTK
Variant Seq.  AIFQsSMTK
Mutations C/S
Epitope Location C5S
HXB2 Location C317S
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A11 restricted. No recognition was seen by CTL from HLA-A3 carriers. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56053

HXB2 Location  Pol(530-538)   Pol Epitope Map
View variants at this location
Epitope IATESIVIW   Epitope Alignment
Variants
IAmESIVIW   observed variant
Epitope Name IW9(RT)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1924
Epitope Seq.  IATESIVIW
Variant Seq.  IAmESIVIW
Mutations T/M
Epitope Location T3M
HXB2 Location T532M
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B58 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55955

HXB2 Location  Pol(547-556)   Pol Epitope Map
View variants at this location
Epitope PIQKETWEAW   Epitope Alignment
Variants
PIQKETWEtW   observed variant
Epitope Name PW10(RT)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1925
Epitope Seq.  PIQKETWEAW
Variant Seq.  PIQKETWEtW
Mutations A/T
Epitope Location A9T
HXB2 Location A555T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A32 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56038

HXB2 Location  Vpr(12-20)   Vpr Epitope Map
View variants at this location
Epitope REPYNEWTL   Epitope Alignment
Variants
REPhNEWTL   observed variant
Epitope Name RL9(Vpr)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1926
Epitope Seq.  REPYNEWTL
Variant Seq.  REPhNEWTL
Mutations Y/H
Epitope Location Y4H
HXB2 Location Y15H
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B40 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55981

HXB2 Location  Vpr(34-42)   Vpr Epitope Map
View variants at this location
Epitope FPRPWLHGL   Epitope Alignment
Variants
FPRiWLHGL   observed variant
Epitope Name FL9(Vpr)
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1927
Epitope Seq.  FPRPWLHGL
Variant Seq.  FPRiWLHGL
Mutations P/I
Epitope Location P4I
HXB2 Location P37I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55969

HXB2 Location  Vpr(48-57)   Vpr Epitope Map
View variants at this location
Epitope ETYGDTWAGV   Epitope Alignment
Variants
ETYGDTWtGV   observed variant
Epitope Name EV10(Vpr)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1928
Epitope Seq.  ETYGDTWAGV
Variant Seq.  ETYGDTWtGV
Mutations A/T
Epitope Location A8T
HXB2 Location A55T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55999

HXB2 Location  Tat(38-47)   Tat Epitope Map
View variants at this location
Epitope FMKKGLGISY   Epitope Alignment
Variants
FqtKGLGISY   observed variant
Epitope Name FY10(Tat)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1929
Epitope Seq.  FMKKGLGISY
Variant Seq.  FqtKGLGISY
Mutations M/Q K/T
Epitope Location M2Q K3T
HXB2 Location M39Q K40T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at two positions. It is predicted to be HLA-B15 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55965

HXB2 Location  Tat(39-49)   Tat Epitope Map
View variants at this location
Epitope MKKGLGISYGR   Epitope Alignment
Variants
itKGLGISYGR   observed variant
Epitope Name IR11(Tat)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1930
Epitope Seq.  MKKGLGISYGR
Variant Seq.  itKGLGISYGR
Mutations M/I K/T
Epitope Location M1I K2T
HXB2 Location M39I K40T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at two positions. It is predicted to be HLA-A68 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56052

HXB2 Location  Rev(14-23)   Rev Epitope Map
View variants at this location
Epitope RTVRLIKLLY   Epitope Alignment
Variants
kaVRLIKLLY   observed variant
Epitope Name KY10(Rev)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1931
Epitope Seq.  RTVRLIKLLY
Variant Seq.  kaVRLIKLLY
Mutations R/K T/A
Epitope Location R1K T2A
HXB2 Location R14K T15A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at two positions. It is predicted to be HLA-B58 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56454

HXB2 Location  Rev(66-75)   Rev Epitope Map
View variants at this location
Epitope RSAEPVPLQL   Epitope Alignment
Variants
RpAEPVPLQL   observed variant
Epitope Name RL10(Rev)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1932
Epitope Seq.  RSAEPVPLQL
Variant Seq.  RpAEPVPLQL
Mutations S/P
Epitope Location S2P
HXB2 Location S67P
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56054

HXB2 Location  gp160(59-69)   gp160 Epitope Map
View variants at this location
Epitope KAYDTEVHNVW   Epitope Alignment
Variants
KAYeTEVHNVW   observed variant
Epitope Name KW11(gp120)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1933
Epitope Seq.  KAYDTEVHNVW
Variant Seq.  KAYeTEVHNVW
Mutations D/E
Epitope Location D4E
HXB2 Location D62E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B58 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55910

HXB2 Location  gp160(311-320)   gp160 Epitope Map
View variants at this location
Epitope LGPGRVWYTT   Epitope Alignment
Variants
rGPGRafvTi   observed variant
Epitope Name RI10(gp120)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1934
Epitope Seq.  LGPGRVWYTT
Variant Seq.  rGPGRafvTi
Mutations L/R T/I V/A W/F Y/V
Epitope Location L1R T10I V6A W7F Y8V
HXB2 Location L311R T320I V316A W317F Y318V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at 5 residues. It is predicted to be HLA-A2 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55951

HXB2 Location  gp160(794-802)   gp160 Epitope Map
View variants at this location
Epitope KYLWNLLQY   Epitope Alignment
Variants
KYcWNLLQY   observed variant
Epitope Name KY9(gp41)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1935
Epitope Seq.  KYLWNLLQY
Variant Seq.  KYcWNLLQY
Mutations L/C
Epitope Location L3C
HXB2 Location L796C
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A30 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55911

HXB2 Location  gp160(813-822)   gp160 Epitope Map
View variants at this location
Epitope SLLNATAIAV   Epitope Alignment
Variants
SLLNATdIAV   observed variant
Epitope Name SV10(gp41)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1936
Epitope Seq.  SLLNATAIAV
Variant Seq.  SLLNATdIAV
Mutations A/D
Epitope Location A7D
HXB2 Location A819D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A2 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55962

HXB2 Location  gp160(831-838)   gp160 Epitope Map
View variants at this location
Epitope EVVQRAYR   Epitope Alignment
Variants
EVaQRAYR   observed variant
Epitope Name ER8(gp41)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1937
Epitope Seq.  EVVQRAYR
Variant Seq.  EVaQRAYR
Mutations V/A
Epitope Location V3A
HXB2 Location V833A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A33 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55982

HXB2 Location  gp160(843-851)   gp160 Epitope Map
View variants at this location
Epitope IPTRIRQGL   Epitope Alignment
Variants
IPrRIRQGL   observed variant
Epitope Name IL9(gp41)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1938
Epitope Seq.  IPTRIRQGL
Variant Seq.  IPrRIRQGL
Mutations T/R
Epitope Location T3R
HXB2 Location T845R
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55974

HXB2 Location  Nef(68-76)   Nef Epitope Map
View variants at this location
Epitope FPVRPQVPL   Epitope Alignment
Variants
FPVtPQVPL   observed variant
Epitope Name FL9(Nef)
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1939
Epitope Seq.  FPVRPQVPL
Variant Seq.  FPVtPQVPL
Mutations R/T
Epitope Location R4T
HXB2 Location R71T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55973

HXB2 Location  Nef(68-77)   Nef Epitope Map
View variants at this location
Epitope FPVRPQVPLR   Epitope Alignment
Variants
FPVtPQVPLR   observed variant
Epitope Name FR10(Nef)
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1940
Epitope Seq.  FPVRPQVPLR
Variant Seq.  FPVtPQVPLR
Mutations R/T
Epitope Location R4T
HXB2 Location R71T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55975

HXB2 Location  Nef(71-79)   Nef Epitope Map
View variants at this location
Epitope RPQVPLRPM   Epitope Alignment
Variants
tPQVPLRPM   observed variant
Epitope Name TM9(Nef)
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1941
Epitope Seq.  RPQVPLRPM
Variant Seq.  tPQVPLRPM
Mutations R/T
Epitope Location R1T
HXB2 Location R71T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55976

HXB2 Location  Nef(77-85)   Nef Epitope Map
View variants at this location
Epitope RPMTYKGAL   Epitope Alignment
Variants
RPMTYKaAv   observed variant
RPMTYKaAL   observed variant
Epitope Name RL9(Nef)
Species (MHC/HLA human(B7)

Variant Details

Showing all: 2 variant(s).


Variant ID.  1942
Epitope Seq.  RPMTYKGAL
Variant Seq.  RPMTYKaAv
Mutations G/A L/V
Epitope Location G7A L9V
HXB2 Location G83A L85V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at two positions. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.


Variant ID.  1943
Epitope Seq.  RPMTYKGAL
Variant Seq.  RPMTYKaAL
Mutations G/A
Epitope Location G7A
HXB2 Location G83A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55901

HXB2 Location  Nef(83-91)   Nef Epitope Map
View variants at this location
Epitope GALDLSFFL   Epitope Alignment
Variants
GAfDLSFFL   observed variant
Epitope Name GL9(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1944
Epitope Seq.  GALDLSFFL
Variant Seq.  GAfDLSFFL
Mutations L/F
Epitope Location L3F
HXB2 Location L85F
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A2 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55915

HXB2 Location  Nef(84-92)   Nef Epitope Map
View variants at this location
Epitope ALDLSHFLK   Epitope Alignment
Variants
AvDLSHFLK   observed variant
Epitope Name AK10(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1945
Epitope Seq.  ALDLSHFLK
Variant Seq.  AvDLSHFLK
Mutations L/V
Epitope Location L2V
HXB2 Location L85V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A3 and -A11 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55988

HXB2 Location  Nef(106-114)   Nef Epitope Map
View variants at this location
Epitope RQDILDLWV   Epitope Alignment
Variants
RQDILDLWi   observed variant
Epitope Name RV9(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1946
Epitope Seq.  RQDILDLWV
Variant Seq.  RQDILDLWi
Mutations V/I
Epitope Location V9I
HXB2 Location V114I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B13 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55978

HXB2 Location  Nef(106-115)   Nef Epitope Map
View variants at this location
Epitope RQDILDLWVY   Epitope Alignment
Variants
RQDILDLWiY   observed variant
Epitope Name RY10(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1947
Epitope Seq.  RQDILDLWVY
Variant Seq.  RQDILDLWiY
Mutations V/I
Epitope Location V9I
HXB2 Location V114I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55979

HXB2 Location  Nef(128-137)   Nef Epitope Map
View variants at this location
Epitope TPGPGRFPL   Epitope Alignment
Variants
TPGPGvryPL   observed variant
Epitope Name TL10(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1948
Epitope Seq.  TPGPGRFPL
Variant Seq.  TPGPGvryPL
Mutations R/V F/R P/Y L/P
Epitope Location R6V F7R P8Y L9P
HXB2 Location R133V F134R P135Y L136P
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at 3 residues. It is predicted to be HLA-B7 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55960

HXB2 Location  Nef(133-141)   Nef Epitope Map
View variants at this location
Epitope GRFPLTFGW   Epitope Alignment
Variants
tRyPLTFGW   observed variant
Epitope Name TW9(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1949
Epitope Seq.  GRFPLTFGW
Variant Seq.  tRyPLTFGW
Mutations G/T F/Y
Epitope Location G1T F3Y
HXB2 Location G133T F135Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at 2 residues. It is predicted to be HLA-A33 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55930

HXB2 Location  Nef(134-141)   Nef Epitope Map
View variants at this location
Epitope RFPLTFGW   Epitope Alignment
Variants
RyPLTFGW   observed variant
Epitope Name RW8(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1950
Epitope Seq.  RFPLTFGW
Variant Seq.  RyPLTFGW
Mutations F/Y
Epitope Location F2Y
HXB2 Location F135Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A24 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55902

HXB2 Location  Nef(136-145)   Nef Epitope Map
View variants at this location
Epitope PLTFGWCFKL   Epitope Alignment
Variants
PLTFGWCyKL   observed variant
Epitope Name PL11(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1951
Epitope Seq.  PLTFGWCFKL
Variant Seq.  PLTFGWCyKL
Mutations F/Y
Epitope Location F8Y
HXB2 Location F143Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-A2 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55903

HXB2 Location  Nef(180-189)   Nef Epitope Map
View variants at this location
Epitope VLMWKFDSRL   Epitope Alignment
Variants
VLeWrFDSRL   observed variant
Epitope Name VL10(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1952
Epitope Seq.  VLMWKFDSRL
Variant Seq.  VLeWrFDSRL
Mutations M/E K/R
Epitope Location M3E K5R
HXB2 Location M182E K184R
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at 2 residues. It is predicted to be HLA-A2 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 55998

HXB2 Location  Nef(183-191)   Nef Epitope Map
View variants at this location
Epitope WKFDSRLAF   Epitope Alignment
Variants
WrFDSRLAF   observed variant
Epitope Name WF9(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1953
Epitope Seq.  WKFDSRLAF
Variant Seq.  WrFDSRLAF
Mutations K/R
Epitope Location K2R
HXB2 Location K184R
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B15 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 56049

HXB2 Location  Nef(188-196)   Nef Epitope Map
View variants at this location
Epitope RLAFHHMAR   Epitope Alignment
Variants
RLAFHHvAR   observed variant
Epitope Name RR9(Nef)
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  1954
Epitope Seq.  RLAFHHMAR
Variant Seq.  RLAFHHvAR
Mutations M/V
Epitope Location M7V
HXB2 Location M194V
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Asian B Clade optimal epitope differs from the consensus B at one position. It is predicted to be HLA-B52 restricted. Experimentally, B clade consensus peptide was used to challenge CTL response in subjects commonly carrying the Asian B-type epitope.

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


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