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Found 10 matching records:

Displaying record number 57722

HXB2 Location  Gag(21-35)   Gag Epitope Map
View variants at this location
Epitope LRPGGKKKYKLKHIV   Epitope Alignment
Variants
LRPGGKKrYKLKHIV   susceptible form
LRPGGKKKYrLKHlV   susceptible form
LRPGGKKKYrLKHIV   susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 3 variant(s).


Variant ID.  2620
Epitope Seq.  LRPGGKKKYKLKHIV
Variant Seq.  LRPGGKKrYKLKHIV
Mutations K/R
Epitope Location K8R
HXB2 Location K28R
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant LRPGGKKrYKLKHIV is seen in patient I04.


Variant ID.  2621
Epitope Seq.  LRPGGKKKYKLKHIV
Variant Seq.  LRPGGKKKYrLKHlV
Mutations I/L K/R
Epitope Location I14L K6R
HXB2 Location I34L K26R
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant LRPGGrKKYKLKHlV is seen in patient I04.


Variant ID.  2622
Epitope Seq.  LRPGGKKKYKLKHIV
Variant Seq.  LRPGGKKKYrLKHIV
Mutations K/R
Epitope Location K10R
HXB2 Location K30R
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant LRPGGKKKYrLKHIV is seen in patient C06.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57719

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTVATL   susceptible form
SLYNTiATL   susceptible form
SLfNTiATL   susceptible form
Species (MHC/HLA human(A*02:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  2617
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVATL
Mutations Y/F
Epitope Location Y3F
HXB2 Location Y79F
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant SLfNTVATL was seen in patient I09.


Variant ID.  2618
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTiATL
Mutations V/I
Epitope Location V6I
HXB2 Location V82I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant SLYNTiAL was seen in patients I11, I07 and C06.


Variant ID.  2619
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiATL
Mutations Y/F V/I
Epitope Location Y3F V6I
HXB2 Location Y79F V82I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant SLfNTiATL was seen in patients I07.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57725

HXB2 Location  Gag(253-272)   Gag Epitope Map
View variants at this location
Epitope NPPIPVGEIYKRWIILGLNK   Epitope Alignment
Variants
NPPIPVGEIYKRWIImGLNK   susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2626
Epitope Seq.  NPPIPVGEIYKRWIILGLNK
Variant Seq.  NPPIPVGEIYKRWIImGLNK
Mutations L/M
Epitope Location L16M
HXB2 Location L268M
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant NPPIPVGEIYKRWIImGLNK was seen in patient C07.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57726

HXB2 Location  Gag(263-282)   Gag Epitope Map
View variants at this location
Epitope KRWIILGLNKIVRMYSPTSI   Epitope Alignment
Variants
KRWIILGLNKIVRMYSPvSI   susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2627
Epitope Seq.  KRWIILGLNKIVRMYSPTSI
Variant Seq.  KRWIILGLNKIVRMYSPvSI
Mutations T/V
Epitope Location T18V
HXB2 Location T280V
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant KRWIILGLNKIVRMYSPvSI is seen in patient I08.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57727

HXB2 Location  Gag(293-312)   Gag Epitope Map
View variants at this location
Epitope FRDYVDRFYKTLRAEQASQE   Epitope Alignment
Variants
FRDYVDRFfKTLRAEQAtQE   susceptible form
FRDYVDqFYKTLRAEQASQE   non-susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  2628
Epitope Seq.  FRDYVDRFYKTLRAEQASQE
Variant Seq.  FRDYVDRFfKTLRAEQAtQE
Mutations S/T Y/F
Epitope Location S18T Y9F
HXB2 Location S310T Y301F
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant FRDYVDRFfKTLRAEQAtQE was seen in patient I08.


Variant ID.  2629
Epitope Seq.  FRDYVDRFYKTLRAEQASQE
Variant Seq.  FRDYVDqFYKTLRAEQASQE
Mutations R/Q
Epitope Location R7Q
HXB2 Location R299Q
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Escape variant FRDYVDqFYKTLRAEQASQE was seen in patient I07, and suppression of this antigen led to a decline in CD38/PD-1 co-expression on CTL.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57732

HXB2 Location  Pol(272-287)   Pol Epitope Map
View variants at this location
Epitope SVPLDKDFRKYTAFTI   Epitope Alignment
Variants
SVPLDeDFRKYTAFTI   non-susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2632
Epitope Seq.  SVPLDKDFRKYTAFTI
Variant Seq.  SVPLDeDFRKYTAFTI
Mutations K/E
Epitope Location K6E
HXB2 Location K277E
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Escape variant SVPLDeDFRKYTAFTI was seen in patient I13, and suppression of the antigen was accompanied by decline in CD38/PD-1 co-expression on CTL.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57723

HXB2 Location  Pol(306-323)   Pol Epitope Map
View variants at this location
Epitope QGWKGSPAIFQSSMTKIL   Epitope Alignment
Variants
QGWKGSPAIFQaSMTKIL   susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2623
Epitope Seq.  QGWKGSPAIFQSSMTKIL
Variant Seq.  QGWKGSPAIFQaSMTKIL
Mutations S/A
Epitope Location S12A
HXB2 Location S317A
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant QGWKGSPAIFQaSMTKIL was found in patient I11.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57724

HXB2 Location  Pol(395-412)   Pol Epitope Map
View variants at this location
Epitope TVQPIVLPEKDSWTVNDI   Epitope Alignment
Variants
TVQPIqLPEKDSWTVNDI   susceptible form
TVQhIqLPEKDiWTVNDI   susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  2624
Epitope Seq.  TVQPIVLPEKDSWTVNDI
Variant Seq.  TVQPIqLPEKDSWTVNDI
Mutations V/Q
Epitope Location V6Q
HXB2 Location V400Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant TVQPIqLPEKDSWTVNDI was carried by patient I11.


Variant ID.  2625
Epitope Seq.  TVQPIVLPEKDSWTVNDI
Variant Seq.  TVQhIqLPEKDiWTVNDI
Mutations S/I P/H V/Q
Epitope Location S12I P4H V6Q
HXB2 Location S406I P398H V400Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Variant TVQhIqLPEKDiWTVNDI was carried by patient I11.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57730

HXB2 Location  Pol(702-717)   Pol Epitope Map
View variants at this location
Epitope QVDKLVSAGIRKVLFL   Epitope Alignment
Variants
QVDKLVSAGIRKiLFL   non-susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2630
Epitope Seq.  QVDKLVSAGIRKVLFL
Variant Seq.  QVDKLVSAGIRKiLFL
Mutations V/I
Epitope Location V13I
HXB2 Location V714I
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Escape variant QVDKLVSAGIRKiLFL was seen in patient I04, and this suppression of antigen was accompanied by a decline in CD38/PD-1 co-expression on HIV-1-specific CTL.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


Displaying record number 57731

HXB2 Location  Pol(827-844)   Pol Epitope Map
View variants at this location
Epitope TIHTDNGSNFTSTTVKAA   Epitope Alignment
Variants
vIHTDNGgNFTSgaVKAA   non-susceptible form
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  2631
Epitope Seq.  TIHTDNGSNFTSTTVKAA
Variant Seq.  vIHTDNGgNFTSgaVKAA
Mutations T/V T/G T/A S/G
Epitope Location T1V T13G T14A S8G
HXB2 Location T827V T839G T840A S834G
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Sequence
Note Escape variant vIHTDNGgNFTSgaVKAA was seen in patient I09, and suppression of this antigen was accompanied by a decline in CD38/PD-1 co-expression on HIV-1-specific CTL.

References

Vollbrecht2010 Thomas Vollbrecht, Heike Brackmann, Nadja Henrich, Joerg Roeling, Ulrich Seybold, Johannes R. Bogner, Frank D. Goebel, and Rika Draenert. Impact of Changes in Antigen Level on CD38/PD-1 Co-Expression on HIV-Specific CD8 T Cells in Chronic, Untreated HIV-1 Infection. J. Med. Virol., 82(3):358-370, Mar 2010. PubMed ID: 20087935. Show all entries for this paper.


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