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Found 16 matching records:

Displaying record number 60604

HXB2 Location  Gag(156-164)   Gag Epitope Map
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Epitope VKVVEEKAF   Epitope Alignment
Variants
VKViEEKAF   HLA association; processing
Epitope Name VF-9
Species (MHC/HLA human(B*15:01, B*15:03)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3522
Epitope Seq.  VKVVEEKAF
Variant Seq.  VKViEEKAF
Mutations V/I
Epitope Location V4I
HXB2 Location V27I
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note Variant VKVIEEKAF , VF-9, had natural processed epitope forms for subtype C, 0% 4h post constitutive proteasome 13% after processing 4h through immuno proteasomes.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60605

HXB2 Location  Gag(156-164)   Gag Epitope Map
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Epitope VKVIEEKAF   Epitope Alignment
Variants
VKVvEEKAF   HLA association; processing
Species (MHC/HLA human(B*15:01, B*15:03)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3524
Epitope Seq.  VKVIEEKAF
Variant Seq.  VKVvEEKAF
Mutations I/V
Epitope Location I4V
HXB2 Location I27V
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Variant VKVvEEKAF , VF-9, was a natural processed epitope form for subtype C.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60606

HXB2 Location  Gag(167-175)   Gag Epitope Map
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Epitope EVIPMFSAL   Epitope Alignment
Variants
EVIPMFtAL   HLA association; processing
Epitope Name EL-9
Species (MHC/HLA human(A*26, A*26:01, A*26:02, A*26:03, C*01, C*01:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3525
Epitope Seq.  EVIPMFSAL
Variant Seq.  EVIPMFtAL
Mutations S/T
Epitope Location S7T
HXB2 Location S41T
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note Variant EVIPMFtAL was of subtype C with natural processed form, AWVKVVEEKAFSPEVIPMFtAL..

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60607

HXB2 Location  Gag(167-175)   Gag Epitope Map
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Epitope EVIPMFTAL   Epitope Alignment
Variants
EVIPMFsAL   HLA association; processing
Species (MHC/HLA human(A*26, A*26:01, A*26:02, A*26:03, C*01, C*01:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3526
Epitope Seq.  EVIPMFTAL
Variant Seq.  EVIPMFsAL
Mutations T/S
Epitope Location T7S
HXB2 Location T173S
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Variant EVIPMFsA, is from fragment F1, subtype B, its natural processed form was AWVKVVEEKAFSPEVIPMFTAL.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60608

HXB2 Location  Gag(240-249)   Gag Epitope Map
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Epitope TSTLQEQIAW   Epitope Alignment
Variants
TSTLQEQIgW   HLA association; processing
Species (MHC/HLA human(B*57, B*57:01, B*57:03, B*58, B*58:01, B*63)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3527
Epitope Seq.  TSTLQEQIAW
Variant Seq.  TSTLQEQIgW
Mutations A/G
Epitope Location A9G
HXB2 Location A248G
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Variant TSTLQEQIgW, is the subtype B form of TW10.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 59315

HXB2 Location  Gag(240-249)   Gag Epitope Map
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Epitope TSTLQEQIGW   Epitope Alignment
Variants
TSTLQEQIaW   HLA association; processing
Epitope Name TW10
Species (MHC/HLA human(B*57:01, B*57:03)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3457
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQIaW
Mutations G/A
Epitope Location G9A
HXB2 Location G248A
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note The subtype C variant TSTLQEQIaW (G116A) was absent from B-infected patients carrying alleles B*3501, B*5802, and B*63. The natural processed form was AGTTSTLQEQIAW, 2% 4h post-constitutive- and 6% post-immuno-proteasomal processing.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60609

HXB2 Location  Gag(254-262)   Gag Epitope Map
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Epitope PPIPVGEIY   Epitope Alignment
Variants
PPIPVGdIY   HLA association; processing
Epitope Name PY-9
Species (MHC/HLA human(B*35, B*35:01, B*35:02, B*53)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3528
Epitope Seq.  PPIPVGEIY
Variant Seq.  PPIPVGdIY
Mutations E/D
Epitope Location E7D
HXB2 Location E128D
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note Subtype C variant, PPIPVGdIY, was processed from natural forms IAWMTSNPPIPVGDIY, MTSNPPIPVGDIY, TSNPPIPVGDIY, SNPPIPVGDIY.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60610

HXB2 Location  Gag(254-262)   Gag Epitope Map
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Epitope PPIPVGDIY   Epitope Alignment
Variants
PPIPVGeIY   HLA association; processing
Species (MHC/HLA human(B*35, B*35:01, B*35:02, B*53)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3529
Epitope Seq.  PPIPVGDIY
Variant Seq.  PPIPVGeIY
Mutations D/E
Epitope Location D7E
HXB2 Location D128E
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Subtype B variant PPIPVGeIY was processed naturally from IGWMTNNPPIPVGEIY, MTNNPPIPVGEIY, TNNPPIPVGEIY, NNPPIPVGEIY, PPIPVGEIY.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60611

HXB2 Location  Gag(259-266)   Gag Epitope Map
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Epitope GEIYKRWI   Epitope Alignment
Variants
GdIYKRWI   HLA association; processing
Epitope Name GI-8
Species (MHC/HLA human(B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3531
Epitope Seq.  GEIYKRWI
Variant Seq.  GdIYKRWI
Mutations E/D
Epitope Location E2D
HXB2 Location E128D
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note Subtype C variant, GdIYKRWI's, natural processed form was TSNPPIPVGDIYKRWI

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60612

HXB2 Location  Gag(259-266)   Gag Epitope Map
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Epitope GDIYKRWI   Epitope Alignment
Variants
GeIYKRWI   HLA association; processing
Species (MHC/HLA human(B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3530
Epitope Seq.  GDIYKRWI
Variant Seq.  GeIYKRWI
Mutations D/E
Epitope Location D2E
HXB2 Location D128E
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Subtype B variant, GeIYKRWI's, natural processed forms were TNNPPIPVGEIYKRWI (proline 122, 123, 125) and VGEIYKRWI.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60613

HXB2 Location  Gag(259-267)   Gag Epitope Map
View variants at this location
Epitope GEIYKRWII   Epitope Alignment
Variants
GdIYKRWII   HLA association; processing
Epitope Name GI-9
Species (MHC/HLA human(B*08, B*08:01, B*40)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3532
Epitope Seq.  GEIYKRWII
Variant Seq.  GdIYKRWII
Mutations E/D
Epitope Location E2D
HXB2 Location E128D
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note GdIYKRWII, the subtype C variant, had natural processed form TSNPPIPVGDIYKRWI.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60614

HXB2 Location  Gag(259-267)   Gag Epitope Map
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Epitope GDIYKRWII   Epitope Alignment
Variants
GeIYKRWII   HLA association; processing
Species (MHC/HLA human(B*08, B*08:01, B*40)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3533
Epitope Seq.  GDIYKRWII
Variant Seq.  GeIYKRWII
Mutations D/E
Epitope Location D2E
HXB2 Location D128E
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note GeIYKRWII is the Subtype B variant.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60617

HXB2 Location  Gag(259-268)   Gag Epitope Map
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Epitope GEIYKRWIIL   Epitope Alignment
Variants
GdIYKRWIIL   HLA association; processing
Epitope Name GL-10
Species (MHC/HLA human(A*24, B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3536
Epitope Seq.  GEIYKRWIIL
Variant Seq.  GdIYKRWIIL
Mutations E/D
Epitope Location E2D
HXB2 Location E128D
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining
Note Subtype C-specific variant is GdIYKRWIIL.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60618

HXB2 Location  Gag(259-268)   Gag Epitope Map
View variants at this location
Epitope GDIYKRWIIL   Epitope Alignment
Variants
GeIYKRWIIL   HLA association; processing
Species (MHC/HLA human(A*24, B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3537
Epitope Seq.  GDIYKRWIIL
Variant Seq.  GeIYKRWIIL
Mutations D/E
Epitope Location D2E
HXB2 Location D128E
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note The subtype B-specific variant is GDIYKRWIIL.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60615

HXB2 Location  Gag(260-267)   Gag Epitope Map
View variants at this location
Epitope EIYKRWII   Epitope Alignment
Variants
dIYKRWII   HLA association; processing
Epitope Name EI-8
Species (MHC/HLA human(B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3534
Epitope Seq.  EIYKRWII
Variant Seq.  dIYKRWII
Mutations E/D
Epitope Location E1D
HXB2 Location E128D
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype C
Method Intracellular cytokine staining, Other
Note Subtype C specific variant dIYKRWII had no determinable natural processed forms.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 60616

HXB2 Location  Gag(260-267)   Gag Epitope Map
View variants at this location
Epitope DIYKRWII   Epitope Alignment
Variants
eIYKRWII   HLA association; processing
Epitope Name DI-8
Species (MHC/HLA human(B*08, B*08:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3535
Epitope Seq.  DIYKRWII
Variant Seq.  eIYKRWII
Mutations D/E
Epitope Location D1E
HXB2 Location D128E
Mutation Type A: HLA association
P: processing
Epitope Subtype C
Variant Subtype B
Method Intracellular cytokine staining
Note Subtype B specific variant eIYKRWII had no determinable natural processed forms.

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


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