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Found 11 matching records:

Displaying record number 101

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLfNTVATL susceptible form

Epitope Name SL9

Species (MHC/HLA) human(A*02:02, A2)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1542`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLfNTVATL`
Mutations	Y/F
Epitope Location	Y3F
HXB2 Location	Y79F
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, SLfNTVATL

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.

Displaying record number 196

HXB2 Location Gag(183-191) Gag Epitope Map
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Epitope

DLNTMLNTV

Epitope Alignment

Variants

DLNnMLNiV susceptible form

Species (MHC/HLA) human(B*14:02, Cw8)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1543`
Epitope Seq.	`DLNTMLNTV`
Variant Seq.	`DLNnMLNiV`
Mutations	T/N T/I
Epitope Location	T4N T8I
HXB2 Location	T186N T190I
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, DLNnMLNiV.

References

Displaying record number 242

HXB2 Location Gag(254-262) Gag Epitope Map
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Epitope

PPIPVGEIY

Epitope Alignment

Variants

PPIPVGdIY susceptible form

Species (MHC/HLA) human(B35)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1544`
Epitope Seq.	`PPIPVGEIY`
Variant Seq.	`PPIPVGdIY`
Mutations	E/D
Epitope Location	E7D
HXB2 Location	E260D
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, PPIPVGdIY.

References

Displaying record number 328

HXB2 Location Gag(298-306) Gag Epitope Map
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Epitope

DRFYKTLRA

Epitope Alignment

Variants

DRFfKTLRA susceptible form

Species (MHC/HLA) human(B*14:02, B14)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1545`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFfKTLRA`
Mutations	Y/F
Epitope Location	Y4F
HXB2 Location	Y301F
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, DTVLEdiNL.

References

Displaying record number 398

HXB2 Location Pol(86-94) Pol Epitope Map
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Epitope

DTVLEEMNL

Epitope Alignment

Variants

DTVLEdiNL observed variant

Species (MHC/HLA) human(A*68:02)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1546`
Epitope Seq.	`DTVLEEMNL`
Variant Seq.	`DTVLEdiNL`
Mutations	E/D M/I
Epitope Location	E6D M7I
HXB2 Location	E91D M92I
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A clade form, DTVLEdiNL.

References

Displaying record number 464

HXB2 Location Pol(330-338) Pol Epitope Map
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Epitope

NPDIVIYQY

Epitope Alignment

Variants

`hPDIVIYQY`		observed variant
`NPeIVIYQY`		observed variant

Species (MHC/HLA) human(B35)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`1547`
Epitope Seq.	`NPDIVIYQY`
Variant Seq.	`hPDIVIYQY`
Mutations	N/H
Epitope Location	N1H
HXB2 Location	N330H
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	One HEPS Kenyan subject cross-reacted to this B clade epitope though it differed from the A clade form, hPDIVIYQY.

Variant ID.	`1548`
Epitope Seq.	`NPDIVIYQY`
Variant Seq.	`NPeIVIYQY`
Mutations	D/E
Epitope Location	D3E
HXB2 Location	D332E
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	D
Method	Chromium-release assay
Note	One HEPS Kenyan subject cross-reacted to this B clade epitope though it differed from the D clade form, NPeIVIYQY.

References

Displaying record number 535

HXB2 Location Pol(464-472) Pol Epitope Map
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Epitope

ILKEPVHGV

Epitope Alignment

Variants

ILKdPVHGV susceptible form

Species (MHC/HLA) human(A*02:02, A2)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1549`
Epitope Seq.	`ILKEPVHGV`
Variant Seq.	`ILKdPVHGV`
Mutations	E/D
Epitope Location	E4D
HXB2 Location	E467D
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, ILKdPVHGV.

References

Displaying record number 833

HXB2 Location gp160(584-592) gp160 Epitope Map
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Epitope

ERYLKDQQL

Epitope Alignment

Variants

ERYLrDQQL susceptible form

Species (MHC/HLA) human(B*14:02, B14)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1550`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`ERYLrDQQL`
Mutations	K/R
Epitope Location	K5R
HXB2 Location	K588R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, ERYLrDQQL.

References

Displaying record number 1056

HXB2 Location Nef(128-137) Nef Epitope Map
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Epitope

TPGPGVRYPL

Epitope Alignment

Variants

TPGPGiRYPL observed variant

Species (MHC/HLA) human(B7)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1551`
Epitope Seq.	`TPGPGVRYPL`
Variant Seq.	`TPGPGiRYPL`
Mutations	V/I
Epitope Location	V6I
HXB2 Location	V133I
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	A, D
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A and D clade form, TPGPGiRYPL.

References

Displaying record number 1072

HXB2 Location Nef(135-143) Nef Epitope Map
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Epitope

YLPTFGWCY

Epitope Alignment

Variants

YLPTFGWCf observed variant

Species (MHC/HLA) human(B49)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`1552`
Epitope Seq.	`YLPTFGWCY`
Variant Seq.	`YLPTFGWCf`
Mutations	Y/F
Epitope Location	Y9F
HXB2 Location	Y143F
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	D
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the D clade form, YLPTFGWCf.

References

Displaying record number 1097

HXB2 Location Nef(190-198) Nef Epitope Map
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Epitope

AFHHVAREL

Epitope Alignment

Variants

`AlkHrAyEL`		observed variant
`AFeHkAREm`		observed variant

Species (MHC/HLA) human(A*02:01, A*02:02, A2)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`1553`
Epitope Seq.	`AFHHVAREL`
Variant Seq.	`AlkHrAyEL`
Mutations	F/L H/K V/R R/Y
Epitope Location	F2L H3K V5R R7Y
HXB2 Location	F191L H192K V194R R196Y
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	A
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A clade form, AlkHrAyEL.

Variant ID.	`1554`
Epitope Seq.	`AFHHVAREL`
Variant Seq.	`AFeHkAREm`
Mutations	H/E V/K L/M
Epitope Location	H3E V5K L9M
HXB2 Location	H192E V194K L198M
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	D
Method	Chromium-release assay
Note	Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the D clade form, AFeHkAREm.