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Found 11 matching records:

Displaying record number 101

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTVATL   susceptible form
Epitope Name SL9
Species (MHC/HLA human(A*02:02, A2)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1542
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVATL
Mutations Y/F
Epitope Location Y3F
HXB2 Location Y79F
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, SLfNTVATL

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 196

HXB2 Location  Gag(183-191)   Gag Epitope Map
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Epitope DLNTMLNTV   Epitope Alignment
Variants
DLNnMLNiV   susceptible form
Species (MHC/HLA human(B*14:02, Cw8)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1543
Epitope Seq.  DLNTMLNTV
Variant Seq.  DLNnMLNiV
Mutations T/N T/I
Epitope Location T4N T8I
HXB2 Location T186N T190I
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, DLNnMLNiV.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 242

HXB2 Location  Gag(254-262)   Gag Epitope Map
View variants at this location
Epitope PPIPVGEIY   Epitope Alignment
Variants
PPIPVGdIY   susceptible form
Species (MHC/HLA human(B35)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1544
Epitope Seq.  PPIPVGEIY
Variant Seq.  PPIPVGdIY
Mutations E/D
Epitope Location E7D
HXB2 Location E260D
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, PPIPVGdIY.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 328

HXB2 Location  Gag(298-306)   Gag Epitope Map
View variants at this location
Epitope DRFYKTLRA   Epitope Alignment
Variants
DRFfKTLRA   susceptible form
Species (MHC/HLA human(B*14:02, B14)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1545
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFfKTLRA
Mutations Y/F
Epitope Location Y4F
HXB2 Location Y301F
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, DTVLEdiNL.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 398

HXB2 Location  Pol(86-94)   Pol Epitope Map
View variants at this location
Epitope DTVLEEMNL   Epitope Alignment
Variants
DTVLEdiNL   observed variant
Species (MHC/HLA human(A*68:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1546
Epitope Seq.  DTVLEEMNL
Variant Seq.  DTVLEdiNL
Mutations E/D M/I
Epitope Location E6D M7I
HXB2 Location E91D M92I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A clade form, DTVLEdiNL.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 464

HXB2 Location  Pol(330-338)   Pol Epitope Map
View variants at this location
Epitope NPDIVIYQY   Epitope Alignment
Variants
hPDIVIYQY   observed variant
NPeIVIYQY   observed variant
Species (MHC/HLA human(B35)

Variant Details

Showing all: 2 variant(s).


Variant ID.  1547
Epitope Seq.  NPDIVIYQY
Variant Seq.  hPDIVIYQY
Mutations N/H
Epitope Location N1H
HXB2 Location N330H
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope though it differed from the A clade form, hPDIVIYQY.


Variant ID.  1548
Epitope Seq.  NPDIVIYQY
Variant Seq.  NPeIVIYQY
Mutations D/E
Epitope Location D3E
HXB2 Location D332E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype D
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope though it differed from the D clade form, NPeIVIYQY.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 535

HXB2 Location  Pol(464-472)   Pol Epitope Map
View variants at this location
Epitope ILKEPVHGV   Epitope Alignment
Variants
ILKdPVHGV   susceptible form
Species (MHC/HLA human(A*02:02, A2)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1549
Epitope Seq.  ILKEPVHGV
Variant Seq.  ILKdPVHGV
Mutations E/D
Epitope Location E4D
HXB2 Location E467D
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope and one of them elicited a stronger reaction to the A clade form, ILKdPVHGV.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 833

HXB2 Location  gp160(584-592)   gp160 Epitope Map
View variants at this location
Epitope ERYLKDQQL   Epitope Alignment
Variants
ERYLrDQQL   susceptible form
Species (MHC/HLA human(B*14:02, B14)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1550
Epitope Seq.  ERYLKDQQL
Variant Seq.  ERYLrDQQL
Mutations K/R
Epitope Location K5R
HXB2 Location K588R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note One HEPS Kenyan subject cross-reacted to this B clade epitope but elicited a stronger reaction to the A clade form, ERYLrDQQL.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 1056

HXB2 Location  Nef(128-137)   Nef Epitope Map
View variants at this location
Epitope TPGPGVRYPL   Epitope Alignment
Variants
TPGPGiRYPL   observed variant
Species (MHC/HLA human(B7)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1551
Epitope Seq.  TPGPGVRYPL
Variant Seq.  TPGPGiRYPL
Mutations V/I
Epitope Location V6I
HXB2 Location V133I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A, D
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A and D clade form, TPGPGiRYPL.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 1072

HXB2 Location  Nef(135-143)   Nef Epitope Map
View variants at this location
Epitope YLPTFGWCY   Epitope Alignment
Variants
YLPTFGWCf   observed variant
Species (MHC/HLA human(B49)

Variant Details

Showing all: 1 variant(s).


Variant ID.  1552
Epitope Seq.  YLPTFGWCY
Variant Seq.  YLPTFGWCf
Mutations Y/F
Epitope Location Y9F
HXB2 Location Y143F
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype D
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the D clade form, YLPTFGWCf.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 1097

HXB2 Location  Nef(190-198)   Nef Epitope Map
View variants at this location
Epitope AFHHVAREL   Epitope Alignment
Variants
AlkHrAyEL   observed variant
AFeHkAREm   observed variant
Species (MHC/HLA human(A*02:01, A*02:02, A2)

Variant Details

Showing all: 2 variant(s).


Variant ID.  1553
Epitope Seq.  AFHHVAREL
Variant Seq.  AlkHrAyEL
Mutations F/L H/K V/R R/Y
Epitope Location F2L H3K V5R R7Y
HXB2 Location F191L H192K V194R R196Y
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype A
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the A clade form, AlkHrAyEL.


Variant ID.  1554
Epitope Seq.  AFHHVAREL
Variant Seq.  AFeHkAREm
Mutations H/E V/K L/M
Epitope Location H3E V5K L9M
HXB2 Location H192E V194K L198M
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype D
Method Chromium-release assay
Note Two HEPS Kenyan subjects cross-reacted to this B clade epitope though it differed from the D clade form, AFeHkAREm.

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


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