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Displaying record number 57652

HXB2 Location  Gag(164-172)   Gag Epitope Map
View variants at this location
Epitope FSPEVIPMF   Epitope Alignment
Variants
FnPEVIPMF   susceptible form
FSPEiIPMF   susceptible form
qSPEVIPMF   susceptible form
FnPEiIPMF   susceptible form
FnPEiIPMF   susceptible form
FSPqVIPMF   susceptible form
Species (MHC/HLA macaque(Mamu-A*01)

Variant Details

Showing all: 6 variant(s).


Variant ID.  2571
Epitope Seq.  FSPEVIPMF
Variant Seq.  FnPEVIPMF
Mutations S/N
Epitope Location S2N
HXB2 Location S165N
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.


Variant ID.  2572
Epitope Seq.  FSPEVIPMF
Variant Seq.  FSPEiIPMF
Mutations V/I
Epitope Location V5I
HXB2 Location V168I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.


Variant ID.  2573
Epitope Seq.  FSPEVIPMF
Variant Seq.  qSPEVIPMF
Mutations F/Q
Epitope Location F1Q
HXB2 Location F164Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.


Variant ID.  2574
Epitope Seq.  FSPEVIPMF
Variant Seq.  FnPEiIPMF
Mutations S/N V/I
Epitope Location S2N V5I
HXB2 Location S165N V168I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.


Variant ID.  2575
Epitope Seq.  FSPEVIPMF
Variant Seq.  FnPEiIPMF
Mutations S/N V/I
Epitope Location S2N V5I
HXB2 Location S165N V168I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.


Variant ID.  2576
Epitope Seq.  FSPEVIPMF
Variant Seq.  FSPqVIPMF
Mutations E/Q
Epitope Location E4Q
HXB2 Location E167Q
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.

References

Rosario2010 Maximillian Rosario, Anne Bridgeman, Esther D. Quakkelaar, Maire F. Quigley, Brenna J. Hill, Maria L. Knudsen, Virginia Ammendola, Karl Ljungberg, Nicola Borthwick, Eung-Jun Im, Andrew J. McMichael, Jan W. Drijfhout, Hui Yee Greenaway, Vanessa Venturi, Daniel C. Douek, Stefano Colloca, Peter Liljeström, Alfredo Nicosia, David A. Price, Cornelis J. M. Melief, and Tomáš Hanke. Long Peptides Induce Polyfunctional T Cells against Conserved Regions of HIV-1 with Superior Breadth to Single-Gene Vaccines in Macaques. Eur. J. Immunol., 40(7):1973-1984, Jul 2010. PubMed ID: 20468055. Show all entries for this paper.


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