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Found 10 matching records:

Displaying record number 62142

HXB2 Location  Gag(141-155)   Gag Epitope Map
View variants at this location
Epitope QMVHQALSPRTLNAW   Epitope Alignment
Variants
QMVHQAiSPRTLNAW   susceptible form
Epitope Name MOS-202
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4208
Epitope Seq.  QMVHQALSPRTLNAW
Variant Seq.  QMVHQAiSPRTLNAW
Mutations L/I
Epitope Location L7I
HXB2 Location L147I
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-3, and is also recognized by HST-NEET cell product from Donor4.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62141

HXB2 Location  Gag(141-155)   Gag Epitope Map
View variants at this location
Epitope QMVHQAISPRTLNAW   Epitope Alignment
Variants
QMVHQAlSPRTLNAW   susceptible form
Epitope Name MOS-3
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4209
Epitope Seq.  QMVHQAISPRTLNAW
Variant Seq.  QMVHQAlSPRTLNAW
Mutations I/L
Epitope Location I7L
HXB2 Location I147L
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-202, and is also recognized by HST-NEET cell product from Donor4.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62137

HXB2 Location  Gag(205-219)   Gag Epitope Map
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Epitope INEEAAEWDRVHPVH   Epitope Alignment
Variants
INEEAAEWDRlHPVH   susceptible form
Epitope Name MOS-19
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4212
Epitope Seq.  INEEAAEWDRVHPVH
Variant Seq.  INEEAAEWDRlHPVH
Mutations V/L
Epitope Location V11L
HXB2 Location V215L
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-218, and is also recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62139

HXB2 Location  Gag(205-219)   Gag Epitope Map
View variants at this location
Epitope INEEAAEWDRLHPVH   Epitope Alignment
Variants
INEEAAEWDRvHPVH   susceptible form
Epitope Name MOS-218
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4213
Epitope Seq.  INEEAAEWDRLHPVH
Variant Seq.  INEEAAEWDRvHPVH
Mutations L/V
Epitope Location L11V
HXB2 Location L215V
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-19, and is also recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62140

HXB2 Location  Gag(209-223)   Gag Epitope Map
View variants at this location
Epitope AAEWDRLHPVHAGPI   Epitope Alignment
Variants
AAEWDRvHPVHAGPI   susceptible form
Epitope Name MOS-219
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4210
Epitope Seq.  AAEWDRLHPVHAGPI
Variant Seq.  AAEWDRvHPVHAGPI
Mutations L/V
Epitope Location L7V
HXB2 Location L215V
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-20, and is recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62138

HXB2 Location  Gag(209-223)   Gag Epitope Map
View variants at this location
Epitope AAEWDRVHPVHAGPI   Epitope Alignment
Variants
AAEWDRlHPVHAGPI   susceptible form
Epitope Name MOS-20
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4211
Epitope Seq.  AAEWDRVHPVHAGPI
Variant Seq.  AAEWDRlHPVHAGPI
Mutations V/L
Epitope Location V7L
HXB2 Location V215L
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-219, and is also recognized by HST-NEET cell product from Donor1.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62143

HXB2 Location  Pol(972-986)   Pol Epitope Map
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Epitope IKVVPRRKVKIIKDY   Epitope Alignment
Variants
IKVVPRRKaKIIrDY   susceptible form
Epitope Name MOS-194
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4214
Epitope Seq.  IKVVPRRKVKIIKDY
Variant Seq.  IKVVPRRKaKIIrDY
Mutations K/R V/A
Epitope Location K13R V9A
HXB2 Location K984R V980A
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-398, and is also recognized by HST-NEET cell product from Donor5.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62144

HXB2 Location  Pol(972-986)   Pol Epitope Map
View variants at this location
Epitope IKVVPRRKAKIIRDY   Epitope Alignment
Variants
IKVVPRRKvKIIkDY   susceptible form
Epitope Name MOS-398
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4215
Epitope Seq.  IKVVPRRKAKIIRDY
Variant Seq.  IKVVPRRKvKIIkDY
Mutations R/K A/V
Epitope Location R13K A9V
HXB2 Location R984K A980V
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-194, and is also recognized by HST-NEET cell product from Donor5.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62145

HXB2 Location  Pol(976-990)   Pol Epitope Map
View variants at this location
Epitope PRRKVKIIKDYGKQM   Epitope Alignment
Variants
PRRKaKIIrDYGKQM   susceptible form
Epitope Name MOS-195
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4216
Epitope Seq.  PRRKVKIIKDYGKQM
Variant Seq.  PRRKaKIIrDYGKQM
Mutations V/A K/R
Epitope Location V5A K9R
HXB2 Location V980A K984R
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-399, and is also recognized by HST-NEET cell product from Donor5.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


Displaying record number 62146

HXB2 Location  Pol(976-990)   Pol Epitope Map
View variants at this location
Epitope PRRKAKIIRDYGKQM   Epitope Alignment
Variants
PRRKvKIIkDYGKQM   susceptible form
Epitope Name MOS-399
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).


Variant ID.  4217
Epitope Seq.  PRRKAKIIRDYGKQM
Variant Seq.  PRRKvKIIkDYGKQM
Mutations A/V R/K
Epitope Location A5V R9K
HXB2 Location A980V R984K
Mutation Type SF: susceptible form
Method Chromium-release assay, Intracellular cytokine staining, Other
Note This variant also in the "bivalent" mosaic epitope mix tHIVconsvX, is one of two variants. It is named MOS-195, and is also recognized by HST-NEET cell product from Donor5.

References

Patel2020 Shabnum Patel, Ryo Hanajiri, Melanie Grant, Devin Saunders, Stacey Van Pelt, Michael Keller, Patrick J. Hanley, Gary Simon, Douglas F. Nixon, David Hardy, R. Brad Jones, and Catherine M. Bollard. HIV-Specific T Cells Can Be Generated against Non-Escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform. Mol. Ther. Methods Clin. Dev., 16:11-20, 13 Mar 2020. PubMed ID: 31720305. Show all entries for this paper.


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