Found 5 matching records:
HXB2 Location | Gag(124-132) | Gag Epitope Map
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Epitope |
NSSKVSQNY
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Epitope Alignment | |||||||||||||||||||
Variants |
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Species (MHC/HLA) | human(A*01:01) |
Showing all: 6 variant(s).
Variant ID. | 4148 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | sSSKVSQNY |
Mutations | N/S |
Epitope Location | N1S |
HXB2 Location | N124S |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 2/5 female A*0101+ patients responded to this novel variant of NSSKVSQNY, sSSKVSQNY, with a mean of 115 SFU/million cells. |
Variant ID. | 4149 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | NSSqVSQNY |
Mutations | K/Q |
Epitope Location | K4Q |
HXB2 Location | K127Q |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 4/5 female A*0101+ patients responded to this variant of NSSKVSQNY, NSSqVSQNY, with a mean of 96 SFU/million cells. |
Variant ID. | 4150 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | NSSqVSrNY |
Mutations | K/Q Q/R |
Epitope Location | K4Q Q7R |
HXB2 Location | K127Q Q130R |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 3/5 female A*0101+ patients responded to this novel variant of NSSKVSQNY, NSSqVSrNY, with a mean of 127 SFU/million cells. |
Variant ID. | 4151 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | hSnqVSQNY |
Mutations | N/H S/N K/Q |
Epitope Location | N1H S3N K4Q |
HXB2 Location | N124H S126N K127Q |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 4/5 female A*0101+ patients responded to this variant of NSSKVSQNY, hSnqVSQNY, with a mean of 115 SFU/million cells. |
Variant ID. | 4152 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | hSSqVSQNY |
Mutations | N/H K/Q |
Epitope Location | N1H K4Q |
HXB2 Location | N124H K127Q |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 4/5 female A*0101+ patients responded to this novel variant of NSSKVSQNY, hSSqVSQNY, with a mean of 74 SFU/million cells. |
Variant ID. | 4153 |
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Epitope Seq. | NSSKVSQNY |
Variant Seq. | sSSqVSQNY |
Mutations | N/S K/Q |
Epitope Location | N1S K4Q |
HXB2 Location | N124S K127Q |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 4/5 female A*0101+ patients responded to this novel variant of NSSKVSQNY, sSSqVSQNY, with a mean of 130 SFU/million cells. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
HXB2 Location | Gag(242-250) | Gag Epitope Map
View variants at this location |
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Epitope |
TPQEQIGWM
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Epitope Alignment | ||||
Variants |
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Species (MHC/HLA) | human(B*07:02) |
Showing all: 1 variant(s).
Variant ID. | 4155 |
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Epitope Seq. | TPQEQIGWM |
Variant Seq. | TPQEQlGWM |
Mutations | I/L |
Epitope Location | I6L |
HXB2 Location | I247L |
Mutation Type | NSF: non-susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | Other, Tetramer binding |
Note | Variant TPQEQlGWM of epitope TPQEQIGWM was a novel epitope based on binding studies and iTope epitope discovery system. It did not bind any of the tested B*0702 subjects, though not all subjects were tested. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
HXB2 Location | Gag(355-363) | Gag Epitope Map
View variants at this location |
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Epitope |
GPGHKARVL
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Epitope Alignment | ||||
Variants |
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Species (MHC/HLA) | human(B*07:02) |
Showing all: 1 variant(s).
Variant ID. | 4154 |
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Epitope Seq. | GPGHKARVL |
Variant Seq. | GPsHKARVL |
Mutations | G/S |
Epitope Location | G3S |
HXB2 Location | G357S |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 9/16 female B*0702+ patients responded to this previously known variant of GPGHKARVL, GPsHKARVL, with a mean of 84 SFU/million cells. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
HXB2 Location | Gag(369-377) | Gag Epitope Map
View variants at this location |
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Epitope |
QVQHTNIMM
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Epitope Alignment | ||||||||||
Variants |
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Species (MHC/HLA) | human(B*07:02) |
Showing all: 3 variant(s).
Variant ID. | 4156 |
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Epitope Seq. | QVQHTNIMM |
Variant Seq. | QaQqpNVMM |
Mutations | V/A H/Q T/P I/V |
Epitope Location | V2A H4Q T5P I7V |
HXB2 Location | V370A H372Q T373P I375V |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 5/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QaQqpNVMM, with a mean of 96 SFU/million cells. |
Variant ID. | 4157 |
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Epitope Seq. | QVQHTNIMM |
Variant Seq. | QanantaIM |
Mutations | V/A Q/N H/A T/N N/T I/A M/I |
Epitope Location | V2A Q3N H4A T5N N6T I7A M8I |
HXB2 Location | V370A Q371N H372A T373N N374T I375A M376I |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 6/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QanantaIM, with a mean of 109 SFU/million cells. |
Variant ID. | 4158 |
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Epitope Seq. | QVQHTNIMM |
Variant Seq. | QVngntaiM |
Mutations | Q/N H/G T/N N/T I/A M/I |
Epitope Location | Q3N H4G T5N N6T I7A M8I |
HXB2 Location | Q371N H372G T373N N374T I375A M376I |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 6/8 female B*7202+ patients responded to this novel variant of QVQHTNIMM, QVngntaiM, with a mean of 99 SFU/million cells. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
HXB2 Location | Gag(375-383) | Gag Epitope Map
View variants at this location |
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Epitope |
NIMMQRGNF
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Epitope Alignment | ||||||||||
Variants |
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Species (MHC/HLA) | human(B*07:02) |
Showing all: 3 variant(s).
Variant ID. | 4159 |
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Epitope Seq. | NIMMQRGNF |
Variant Seq. | NIMMQRsNF |
Mutations | G/S |
Epitope Location | G7S |
HXB2 Location | G381S |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 6/8 female B*7202+ patients responded to this novel variant of NIMMQRGNF, NIMMQRsNF, with a mean of 121 SFU/million cells. |
Variant ID. | 4160 |
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Epitope Seq. | NIMMQRGNF |
Variant Seq. | NvMMQRsNF |
Mutations | I/V G/S |
Epitope Location | I2V G7S |
HXB2 Location | I376V G381S |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 6/8 female B*7202+ patients responded to this novel variant of NIMMQRGNF, NvMMQRsNF, with a mean of 117 SFU/million cells. |
Variant ID. | 4161 |
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Epitope Seq. | NIMMQRGNF |
Variant Seq. | aIMMQRGNF |
Mutations | N/A |
Epitope Location | N1A |
HXB2 Location | N375A |
Mutation Type | SF: susceptible form |
Epitope Subtype | A, D |
Variant Subtype | A, D |
Method | CD8 T-cell Elispot - IFNy, Other, Tetramer binding |
Note | 4/8 female B*7202+ patients responded to this novel variant of NIMMQRGNF, aIMMQRGNF, with a mean of 113 SFU/million cells. |
Luo2012 Ma Luo, Christina A. Daniuk, Tamsir O. Diallo, Rupert E. Capina, Joshua Kimani, Charles Wachihi, Makubo Kimani, Thomas Bielawny, Trevor Peterson, Mark G. R. Mendoza, Sandra Kiazyk, T. Blake Ball, and Francis A. Plummer. For Protection from HIV-1 Infection, More Might Not Be Better: A Systematic Analysis of HIV Gag Epitopes of Two Alleles Associated with Different Outcomes of HIV-1 Infection. J. Virol., 86(2):1166-1180, Jan 2012. PubMed ID: 22072744. Show all entries for this paper.
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