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Found 16 matching records:

Displaying record number 59074

HXB2 Location  Gag(203-212)   Gag Epitope Map
View variants at this location
Epitope ETINEEAAEW   Epitope Alignment
Variants
ETINdEAAEW   diminished response
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3247
Epitope Seq.  ETINEEAAEW
Variant Seq.  ETINdEAAEW
Mutations E/D
Epitope Location E5D
HXB2 Location E207D
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 27, suggesting partial escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59082

HXB2 Location  Pol(24-31)   Pol Epitope Map
View variants at this location
Epitope NSPTRREL   Epitope Alignment
Variants
NSPTsptRREL   escape documented in this paper; insertion
tSPTRREL   escape documented in this paper
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3248
Epitope Seq.  NSPTRREL
Variant Seq.  NSPTsptRREL
Mutations -/S -/P -/T
Epitope Location -(4.1)S -(4.2)P -(4.3)T
HXB2 Location -(27.1)S -(27.2)P -(27.3)T
Mutation Type E: escape documented in this paper
I: insertion
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3249
Epitope Seq.  NSPTRREL
Variant Seq.  tSPTRREL
Mutations N/T
Epitope Location N1T
HXB2 Location N24T
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59083

HXB2 Location  Pol(283-290)   Pol Epitope Map
View variants at this location
Epitope TAFTIPSI   Epitope Alignment
Variants
TAFTIPSt   diminished response
TAFTIPSr   diminished response
TAFTIPSv   diminished response
Species (MHC/HLA human(B*51:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3250
Epitope Seq.  TAFTIPSI
Variant Seq.  TAFTIPSt
Mutations I/T
Epitope Location I8T
HXB2 Location I290T
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = >100, suggesting partial escape.


Variant ID.  3251
Epitope Seq.  TAFTIPSI
Variant Seq.  TAFTIPSr
Mutations I/R
Epitope Location I8R
HXB2 Location I290R
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope, EC50ratio = >100, suggesting partial escape.


Variant ID.  3252
Epitope Seq.  TAFTIPSI
Variant Seq.  TAFTIPSv
Mutations I/V
Epitope Location I8V
HXB2 Location I290V
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = >100, suggesting partial escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59084

HXB2 Location  Pol(291-299)   Pol Epitope Map
View variants at this location
Epitope NNETPGVRY   Epitope Alignment
Variants
NNgTPGVRY   diminished response
Species (MHC/HLA human(B*18:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3253
Epitope Seq.  NNETPGVRY
Variant Seq.  NNgTPGVRY
Mutations E/G
Epitope Location E3G
HXB2 Location E293G
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 22, suggesting partial escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59085

HXB2 Location  Pol(359-367)   Pol Epitope Map
View variants at this location
Epitope ELRQHLLRW   Epitope Alignment
Variants
ELRQHLLkW   escape documented in this paper
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3254
Epitope Seq.  ELRQHLLRW
Variant Seq.  ELRQHLLkW
Mutations R/K
Epitope Location R8K
HXB2 Location R366K
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59086

HXB2 Location  Vpr(29-37)   Vpr Epitope Map
View variants at this location
Epitope EAVRHFPRI   Epitope Alignment
Variants
EAVRHFPRt   diminished response
EAVRHFPRl   diminished response
Species (MHC/HLA human(B*51:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3255
Epitope Seq.  EAVRHFPRI
Variant Seq.  EAVRHFPRt
Mutations I/T
Epitope Location I9T
HXB2 Location I37T
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 43, suggesting partial escape.


Variant ID.  3256
Epitope Seq.  EAVRHFPRI
Variant Seq.  EAVRHFPRl
Mutations I/L
Epitope Location I9L
HXB2 Location I37L
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 18, suggesting partial escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59088

HXB2 Location  Tat(3-11)   Tat Epitope Map
View variants at this location
Epitope PVDPRLEPW   Epitope Alignment
Variants
PVDPRLdPW   escape documented in this paper
PVDPsLEPW   escape documented in this paper
PVDPkLEPW   escape documented in this paper
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3257
Epitope Seq.  PVDPRLEPW
Variant Seq.  PVDPRLdPW
Mutations E/D
Epitope Location E7D
HXB2 Location E9D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3258
Epitope Seq.  PVDPRLEPW
Variant Seq.  PVDPsLEPW
Mutations R/S
Epitope Location R5S
HXB2 Location R7S
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3259
Epitope Seq.  PVDPRLEPW
Variant Seq.  PVDPkLEPW
Mutations R/K
Epitope Location R5K
HXB2 Location R7K
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59089

HXB2 Location  Tat(30-37)   Tat Epitope Map
View variants at this location
Epitope CCFHCQVC   Epitope Alignment
Variants
CClHCQVC   escape documented in this paper
CCFHCQsC   escape documented in this paper
Species (MHC/HLA human(C*12:03)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3260
Epitope Seq.  CCFHCQVC
Variant Seq.  CClHCQVC
Mutations F/L
Epitope Location F3L
HXB2 Location F32L
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3261
Epitope Seq.  CCFHCQVC
Variant Seq.  CCFHCQsC
Mutations V/S
Epitope Location V7S
HXB2 Location V36S
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59090

HXB2 Location  gp160(31-39)   gp160 Epitope Map
View variants at this location
Epitope AENLWVTVY   Epitope Alignment
Variants
TEdLWVTVY   escape documented in this paper
eEDLWVTVY   escape documented in this paper
AEdsWVTVY   escape documented in this paper
Species (MHC/HLA human(B*18:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3262
Epitope Seq.  AENLWVTVY
Variant Seq.  TEdLWVTVY
Mutations A/T N/D
Epitope Location A1T N3D
HXB2 Location A31T N33D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3263
Epitope Seq.  AENLWVTVY
Variant Seq.  eEDLWVTVY
Mutations A/E N/D
Epitope Location A1E N3D
HXB2 Location A31E N33D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3264
Epitope Seq.  AENLWVTVY
Variant Seq.  AEdsWVTVY
Mutations N/D L/S
Epitope Location N3D L4S
HXB2 Location N33D L34S
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59091

HXB2 Location  gp160(61-69)   gp160 Epitope Map
View variants at this location
Epitope YETEVHNVW   Epitope Alignment
Variants
YgTEVHNVW   diminished response
YdTEVHNVW   diminished response
YdTEaHNVW   diminished response
Species (MHC/HLA human(B*18:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3265
Epitope Seq.  YETEVHNVW
Variant Seq.  YgTEVHNVW
Mutations E/G
Epitope Location E2G
HXB2 Location E62G
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 22, suggesting partial escape.


Variant ID.  3266
Epitope Seq.  YETEVHNVW
Variant Seq.  YdTEVHNVW
Mutations E/D
Epitope Location E2D
HXB2 Location E62D
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 13, suggesting partial escape.


Variant ID.  3267
Epitope Seq.  YETEVHNVW
Variant Seq.  YdTEaHNVW
Mutations E/D V/A
Epitope Location E2D V5A
HXB2 Location E62D V65A
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = >83, suggesting partial escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59092

HXB2 Location  gp160(88-96)   gp160 Epitope Map
View variants at this location
Epitope NVTENFNMW   Epitope Alignment
Variants
NVTEdFdMW   escape documented in this paper
NVTEeFdMW   escape documented in this paper
NVTEsFdMW   escape documented in this paper
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  3268
Epitope Seq.  NVTENFNMW
Variant Seq.  NVTEdFdMW
Mutations N/D N/D
Epitope Location N5D N7D
HXB2 Location N92D N94D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3269
Epitope Seq.  NVTENFNMW
Variant Seq.  NVTEeFdMW
Mutations N/E N/D
Epitope Location N5E N7D
HXB2 Location N92E N94D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3270
Epitope Seq.  NVTENFNMW
Variant Seq.  NVTEsFdMW
Mutations N/S N/D
Epitope Location N5S N7D
HXB2 Location N92S N94D
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59093

HXB2 Location  gp160(217-226)   gp160 Epitope Map
View variants at this location
Epitope YCAPAGFAIL   Epitope Alignment
Variants
YCAPAGFAIi   escape documented in this paper
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3271
Epitope Seq.  YCAPAGFAIL
Variant Seq.  YCAPAGFAIi
Mutations L/I
Epitope Location L10I
HXB2 Location L226I
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59094

HXB2 Location  gp160(321-330)   gp160 Epitope Map
View variants at this location
Epitope EIIGDIRQAY   Epitope Alignment
Variants
qIIGDIRQAY   diminished response
dIIGDIRQAh   diminished response
EIIGnIRQAh   diminished response
EIIGDIRQAh   escape documented in this paper
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 4 variant(s).


Variant ID.  3272
Epitope Seq.  EIIGDIRQAY
Variant Seq.  qIIGDIRQAY
Mutations E/Q
Epitope Location E1Q
HXB2 Location E321Q
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = >200, suggesting partial escape.


Variant ID.  3273
Epitope Seq.  EIIGDIRQAY
Variant Seq.  dIIGDIRQAh
Mutations E/D Y/H
Epitope Location E1D Y10H
HXB2 Location E321D Y330H
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 34, suggesting partial escape.


Variant ID.  3274
Epitope Seq.  EIIGDIRQAY
Variant Seq.  EIIGnIRQAh
Mutations Y/H D/N
Epitope Location Y10H D5N
HXB2 Location Y330H D325N
Mutation Type DR: diminished response
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note Ratio of EliSpot peptide titration of this mutant to original epitope EC50ratio = 15.9, suggesting partial escape.


Variant ID.  3275
Epitope Seq.  EIIGDIRQAY
Variant Seq.  EIIGDIRQAh
Mutations Y/H
Epitope Location Y10H
HXB2 Location Y330H
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59095

HXB2 Location  gp160(341-349)   gp160 Epitope Map
View variants at this location
Epitope TLSQIVTKL   Epitope Alignment
Variants
TLSkIVTKL   escape documented in this paper
Species (MHC/HLA human(A*02:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3276
Epitope Seq.  TLSQIVTKL
Variant Seq.  TLSkIVTKL
Mutations Q/K
Epitope Location Q4K
HXB2 Location Q344K
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59096

HXB2 Location  gp160(712-720)   gp160 Epitope Map
View variants at this location
Epitope YSPLSLQTL   Epitope Alignment
Variants
YSPLSLQTr   escape documented in this paper
Species (MHC/HLA human(C*01:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  3277
Epitope Seq.  YSPLSLQTL
Variant Seq.  YSPLSLQTr
Mutations L/R
Epitope Location L9R
HXB2 Location L720R
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


Displaying record number 59097

HXB2 Location  Nef(5-13)   Nef Epitope Map
View variants at this location
Epitope WSKSSIIGW   Epitope Alignment
Variants
WSKtSIIGW   escape documented in this paper
WSKSSmIGW   escape documented in this paper
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  3278
Epitope Seq.  WSKSSIIGW
Variant Seq.  WSKtSIIGW
Mutations S/T
Epitope Location S4T
HXB2 Location S8T
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.


Variant ID.  3279
Epitope Seq.  WSKSSIIGW
Variant Seq.  WSKSSmIGW
Mutations I/M
Epitope Location I6M
HXB2 Location I10M
Mutation Type E: escape documented in this paper
Epitope Subtype B
Variant Subtype B
Method Peptide titration
Note EliSpot peptide titration indicated full escape.

References

Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.


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