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Found 3 matching records:

Displaying record number 53742

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTVATL   observed variant
SLYNTiATL   observed variant
Species (MHC/HLA human(A2)

Variant Details

Showing all: 2 variant(s).


Variant ID.  500
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVATL
Mutations Y/F
Epitope Location Y3F
HXB2 Location Y79F
Mutation Type OV: observed variant
Note Two of the subjects carried this variant of the epitope


Variant ID.  501
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTiATL
Mutations V/I
Epitope Location V6I
HXB2 Location V82I
Mutation Type OV: observed variant
Note One of the subjects carried this variant of the epitope.

References

Jansen2005a Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, and Debbie van Baarle. High Responsiveness of HLA-B57-Restricted Gag-Specific CD8+ T Cells In Vitro May Contribute to the Protective Effect of HLA-B57 in HIV-Infection. Eur. J. Immunol., 35(1):150-158, Jan 2005. PubMed ID: 15593302. Show all entries for this paper.


Displaying record number 53741

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KvFSPEVIPMF   observed variant
eAFSPEVIPMF   observed variant
KtFSPEVIPMF   observed variant
Epitope Name KAF
Species (MHC/HLA human(B57)

Variant Details

Showing all: 3 variant(s).


Variant ID.  502
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KvFSPEVIPMF
Mutations A/V
Epitope Location A2V
HXB2 Location A163V
Mutation Type OV: observed variant
Note Variant was found in 2/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.


Variant ID.  503
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  eAFSPEVIPMF
Mutations K/E
Epitope Location K1E
HXB2 Location K162E
Mutation Type OV: observed variant
Note Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.


Variant ID.  504
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KtFSPEVIPMF
Mutations A/T
Epitope Location A2T
HXB2 Location A163T
Mutation Type OV: observed variant
Note Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

References

Jansen2005a Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, and Debbie van Baarle. High Responsiveness of HLA-B57-Restricted Gag-Specific CD8+ T Cells In Vitro May Contribute to the Protective Effect of HLA-B57 in HIV-Infection. Eur. J. Immunol., 35(1):150-158, Jan 2005. PubMed ID: 15593302. Show all entries for this paper.


Displaying record number 53743

HXB2 Location  Gag(260-267)   Gag Epitope Map
View variants at this location
Epitope EIYRKWII   Epitope Alignment
Variants
EfYRKWII   observed variant
rIYRKWII   observed variant
Species (MHC/HLA human(B8)

Variant Details

Showing all: 2 variant(s).


Variant ID.  505
Epitope Seq.  EIYRKWII
Variant Seq.  EfYRKWII
Mutations I/F
Epitope Location I2F
HXB2 Location I261F
Mutation Type OV: observed variant
Note Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.


Variant ID.  506
Epitope Seq.  EIYRKWII
Variant Seq.  rIYRKWII
Mutations E/R
Epitope Location E1R
HXB2 Location E260R
Mutation Type OV: observed variant
Note Variant was found in 1/5 B57+ individuals, but was always in a minor form. The frequency of the epitope mutation did not correlate with the percentage of IFN-gamma producing CTLs.

References

Jansen2005a Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, and Debbie van Baarle. High Responsiveness of HLA-B57-Restricted Gag-Specific CD8+ T Cells In Vitro May Contribute to the Protective Effect of HLA-B57 in HIV-Infection. Eur. J. Immunol., 35(1):150-158, Jan 2005. PubMed ID: 15593302. Show all entries for this paper.


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