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Found 6 matching records:

Displaying record number 62254

HXB2 Location Gag(18-26) Gag Epitope Map
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KIRLRPGGK

`KIRLRPGGn`		susceptible form
`KIRLRPeGK`		susceptible form
`KIkLRPGGK`		susceptible form
`KIqLRPGGK`		susceptible form
`KIkLRPGGr`		susceptible form

Species (MHC/HLA) human(A*03)

Variant Details

Showing all: 5 variant(s).

Variant ID.	`4369`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIRLRPGGn`
Mutations	K/N
Epitope Location	K9N
HXB2 Location	K26N
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIRLRPGGn was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4370`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIRLRPeGK`
Mutations	G/E
Epitope Location	G7E
HXB2 Location	G24E
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIRLRPeGk was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4371`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIkLRPGGK`
Mutations	R/K
Epitope Location	R3K
HXB2 Location	R20K
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIkLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4372`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIqLRPGGK`
Mutations	R/Q
Epitope Location	R3Q
HXB2 Location	R20Q
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIqLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4373`
Epitope Seq.	`KIRLRPGGK`
Variant Seq.	`KIkLRPGGr`
Mutations	R/K K/R
Epitope Location	R3K K9R
HXB2 Location	R20K K26R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KIkLRPGGr was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.

Displaying record number 323

HXB2 Location Gag(298-306) Gag Epitope Map
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Epitope

DRFYKTLRA

Epitope Alignment

Variants

`DRFwKTLRA`		susceptible form
`DRFfKTLRA`		susceptible form
`DRFYKTvRA`		susceptible form
`DRFYKTiRA`		susceptible form
`DRFYKTmRA`		susceptible form

Species (MHC/HLA) human(B*14)

Variant Details

Showing all: 5 variant(s).

Variant ID.	`4350`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFwKTLRA`
Mutations	Y/W
Epitope Location	Y4W
HXB2 Location	Y301W
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope DRFwKTLRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4351`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFfKTLRA`
Mutations	Y/F
Epitope Location	Y4F
HXB2 Location	Y301F
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope DRFfKTLRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4352`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFYKTvRA`
Mutations	L/V
Epitope Location	L7V
HXB2 Location	L304V
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope DRFYKTvRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4354`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFYKTiRA`
Mutations	L/I
Epitope Location	L7I
HXB2 Location	L304I
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope DRFYKTiRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4355`
Epitope Seq.	`DRFYKTLRA`
Variant Seq.	`DRFYKTmRA`
Mutations	L/M
Epitope Location	L7M
HXB2 Location	L304M
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope DRFYKTmRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Displaying record number 551

HXB2 Location Pol(547-556) Pol Epitope Map
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Epitope

PIQKETWETW

Epitope Alignment

Variants

`PIQKETWEaW`		susceptible form
`PIQKEaWETW`		susceptible form
`PIQKETWdaW`		susceptible form

Species (MHC/HLA) human(A*32:01)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`1275`
Epitope Seq.	`PIQKETWETW`
Variant Seq.	`PIQKETWEaW`
Mutations	T/A
Epitope Location	T9A
HXB2 Location	T555A
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope PIQKETWEaW was able to elicit a lytic response from Subject 15160's CTL and it was found in 6/7 samples of subject's autologous viral sequences.

Variant ID.	`4356`
Epitope Seq.	`PIQKETWETW`
Variant Seq.	`PIQKEaWETW`
Mutations	T/A
Epitope Location	T6A
HXB2 Location	T552A
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	This variant, PIQKEaWETW, was detected in a mother-infant transmission study. The variant was recognized by index epitope-specific CTL clones.

Variant ID.	`4357`
Epitope Seq.	`PIQKETWETW`
Variant Seq.	`PIQKETWdaW`
Mutations	E/D T/A
Epitope Location	E8D T9A
HXB2 Location	E554D T555A
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope PIQKETWdaW was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.

Displaying record number 791

HXB2 Location gp160(419-427) gp160 Epitope Map
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Epitope

RIKQIINMW

Epitope Alignment

Variants

`RIKQfINMW`		non-susceptible form
`RIKQIvNMW`		susceptible form

Species (MHC/HLA) human(A*32:01)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`4358`
Epitope Seq.	`RIKQIINMW`
Variant Seq.	`RIKQfINMW`
Mutations	I/F
Epitope Location	I5F
HXB2 Location	I423F
Mutation Type	NSF: non-susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope RIKQfINMW was unable to elicit a lytic response from Subject 15160's CTL though. It was not found in the subject's autologous viral sequences.

Variant ID.	`4359`
Epitope Seq.	`RIKQIINMW`
Variant Seq.	`RIKQIvNMW`
Mutations	I/V
Epitope Location	I6V
HXB2 Location	I424V
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope RIKQIvNMW was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-RF strain.

References

Displaying record number 62252

HXB2 Location gp160(584-592) gp160 Epitope Map
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Epitope

ERYLKDQQL

Epitope Alignment

Variants

`ERYLrDQQL`		susceptible form
`ERYLqDQQL`		susceptible form
`EkYLqDQarl`		non-susceptible form
`EkYLKDQaQl`		diminished response; non-susceptible form
`ERYLqDQrL`		susceptible form

Species (MHC/HLA) human(B*14)

Variant Details

Showing all: 5 variant(s).

Variant ID.	`4360`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`ERYLrDQQL`
Mutations	K/R
Epitope Location	K5R
HXB2 Location	K588R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope ERYLrDQQL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-RF strain.

Variant ID.	`4361`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`ERYLqDQQL`
Mutations	K/Q
Epitope Location	K5Q
HXB2 Location	K588Q
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope ERYLqDQQL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4362`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`EkYLqDQarl`
Mutations	R/K K/Q Q/A L/R
Epitope Location	R2K K5Q Q8A L9R
HXB2 Location	R585K K588Q Q591A L592R
Mutation Type	NSF: non-susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope EkYLqDQarl was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences. It is the autologous sequence of HIV-2.

Variant ID.	`4363`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`EkYLKDQaQl`
Mutations	R/K Q/A L/Q
Epitope Location	R2K Q8A L9Q
HXB2 Location	R585K Q591A L592Q
Mutation Type	DR: diminished response NSF: non-susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope EkYLKDQaQl was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences. It is the autologous sequence of SIV!

Variant ID.	`4364`
Epitope Seq.	`ERYLKDQQL`
Variant Seq.	`ERYLqDQrL`
Mutations	K/Q Q/R
Epitope Location	K5Q Q8R
HXB2 Location	K588Q Q591R
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope ERYLqDQrL was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences.

References

Displaying record number 62253

HXB2 Location Nef(82-91) Nef Epitope Map
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Epitope

KAAVDLSHFL

Epitope Alignment

Variants

`KAAlDLSHFL`		susceptible form
`KAAlDiSHFL`		susceptible form
`KgAVDLSHFL`		susceptible form
`KgAlDLSHFL`		susceptible form

Species (MHC/HLA) human(C*08)

Variant Details

Showing all: 4 variant(s).

Variant ID.	`4365`
Epitope Seq.	`KAAVDLSHFL`
Variant Seq.	`KAAlDLSHFL`
Mutations	V/L
Epitope Location	V4L
HXB2 Location	V85L
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KAAlDLSHFL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

Variant ID.	`4366`
Epitope Seq.	`KAAVDLSHFL`
Variant Seq.	`KAAlDiSHFL`
Mutations	V/L L/I
Epitope Location	V4L L6I
HXB2 Location	V85L L87I
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KAAlDiSHFL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-1 SF2 strain.

Variant ID.	`4367`
Epitope Seq.	`KAAVDLSHFL`
Variant Seq.	`KgAVDLSHFL`
Mutations	A/G
Epitope Location	A2G
HXB2 Location	A83G
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KgAVDLSHFL was able to elicit a lytic response from Subject 15160's CTL and it was found in 4/5 samples of the subject's autologous sequences.

Variant ID.	`4368`
Epitope Seq.	`KAAVDLSHFL`
Variant Seq.	`KgAlDLSHFL`
Mutations	A/G V/L
Epitope Location	A2G V4L
HXB2 Location	A83G V85L
Mutation Type	SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Variant epitope KgAlDLSHFL was able to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous sequences.