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Found 6 matching records:

Displaying record number 62254

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
Variants
KIRLRPGGn   susceptible form
KIRLRPeGK   susceptible form
KIkLRPGGK   susceptible form
KIqLRPGGK   susceptible form
KIkLRPGGr   susceptible form
Species (MHC/HLA human(A*03)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4369
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPGGn
Mutations K/N
Epitope Location K9N
HXB2 Location K26N
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIRLRPGGn was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4370
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIRLRPeGK
Mutations G/E
Epitope Location G7E
HXB2 Location G24E
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIRLRPeGk was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4371
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIkLRPGGK
Mutations R/K
Epitope Location R3K
HXB2 Location R20K
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIkLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4372
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIqLRPGGK
Mutations R/Q
Epitope Location R3Q
HXB2 Location R20Q
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIqLRPGGK was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4373
Epitope Seq.  KIRLRPGGK
Variant Seq.  KIkLRPGGr
Mutations R/K K/R
Epitope Location R3K K9R
HXB2 Location R20K K26R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KIkLRPGGr was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


Displaying record number 323

HXB2 Location  Gag(298-306)   Gag Epitope Map
View variants at this location
Epitope DRFYKTLRA   Epitope Alignment
Variants
DRFwKTLRA   susceptible form
DRFfKTLRA   susceptible form
DRFYKTvRA   susceptible form
DRFYKTiRA   susceptible form
DRFYKTmRA   susceptible form
Species (MHC/HLA human(B*14)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4350
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFwKTLRA
Mutations Y/W
Epitope Location Y4W
HXB2 Location Y301W
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope DRFwKTLRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4351
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFfKTLRA
Mutations Y/F
Epitope Location Y4F
HXB2 Location Y301F
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope DRFfKTLRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4352
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFYKTvRA
Mutations L/V
Epitope Location L7V
HXB2 Location L304V
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope DRFYKTvRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4354
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFYKTiRA
Mutations L/I
Epitope Location L7I
HXB2 Location L304I
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope DRFYKTiRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4355
Epitope Seq.  DRFYKTLRA
Variant Seq.  DRFYKTmRA
Mutations L/M
Epitope Location L7M
HXB2 Location L304M
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope DRFYKTmRA was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


Displaying record number 551

HXB2 Location  Pol(547-556)   Pol Epitope Map
View variants at this location
Epitope PIQKETWETW   Epitope Alignment
Variants
PIQKETWEaW   susceptible form
PIQKEaWETW   susceptible form
PIQKETWdaW   susceptible form
Species (MHC/HLA human(A*32:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  1275
Epitope Seq.  PIQKETWETW
Variant Seq.  PIQKETWEaW
Mutations T/A
Epitope Location T9A
HXB2 Location T555A
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope PIQKETWEaW was able to elicit a lytic response from Subject 15160's CTL and it was found in 6/7 samples of subject's autologous viral sequences.


Variant ID.  4356
Epitope Seq.  PIQKETWETW
Variant Seq.  PIQKEaWETW
Mutations T/A
Epitope Location T6A
HXB2 Location T552A
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note This variant, PIQKEaWETW, was detected in a mother-infant transmission study. The variant was recognized by index epitope-specific CTL clones.


Variant ID.  4357
Epitope Seq.  PIQKETWETW
Variant Seq.  PIQKETWdaW
Mutations E/D T/A
Epitope Location E8D T9A
HXB2 Location E554D T555A
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope PIQKETWdaW was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


Displaying record number 791

HXB2 Location  gp160(419-427)   gp160 Epitope Map
View variants at this location
Epitope RIKQIINMW   Epitope Alignment
Variants
RIKQfINMW   non-susceptible form
RIKQIvNMW   susceptible form
Species (MHC/HLA human(A*32:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  4358
Epitope Seq.  RIKQIINMW
Variant Seq.  RIKQfINMW
Mutations I/F
Epitope Location I5F
HXB2 Location I423F
Mutation Type NSF: non-susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope RIKQfINMW was unable to elicit a lytic response from Subject 15160's CTL though. It was not found in the subject's autologous viral sequences.


Variant ID.  4359
Epitope Seq.  RIKQIINMW
Variant Seq.  RIKQIvNMW
Mutations I/V
Epitope Location I6V
HXB2 Location I424V
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope RIKQIvNMW was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-RF strain.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


Displaying record number 62252

HXB2 Location  gp160(584-592)   gp160 Epitope Map
View variants at this location
Epitope ERYLKDQQL   Epitope Alignment
Variants
ERYLrDQQL   susceptible form
ERYLqDQQL   susceptible form
EkYLqDQarl   non-susceptible form
EkYLKDQaQl   diminished response; non-susceptible form
ERYLqDQrL   susceptible form
Species (MHC/HLA human(B*14)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4360
Epitope Seq.  ERYLKDQQL
Variant Seq.  ERYLrDQQL
Mutations K/R
Epitope Location K5R
HXB2 Location K588R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope ERYLrDQQL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-RF strain.


Variant ID.  4361
Epitope Seq.  ERYLKDQQL
Variant Seq.  ERYLqDQQL
Mutations K/Q
Epitope Location K5Q
HXB2 Location K588Q
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope ERYLqDQQL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4362
Epitope Seq.  ERYLKDQQL
Variant Seq.  EkYLqDQarl
Mutations R/K K/Q Q/A L/R
Epitope Location R2K K5Q Q8A L9R
HXB2 Location R585K K588Q Q591A L592R
Mutation Type NSF: non-susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope EkYLqDQarl was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences. It is the autologous sequence of HIV-2.


Variant ID.  4363
Epitope Seq.  ERYLKDQQL
Variant Seq.  EkYLKDQaQl
Mutations R/K Q/A L/Q
Epitope Location R2K Q8A L9Q
HXB2 Location R585K Q591A L592Q
Mutation Type DR: diminished response
NSF: non-susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope EkYLKDQaQl was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences. It is the autologous sequence of SIV!


Variant ID.  4364
Epitope Seq.  ERYLKDQQL
Variant Seq.  ERYLqDQrL
Mutations K/Q Q/R
Epitope Location K5Q Q8R
HXB2 Location K588Q Q591R
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope ERYLqDQrL was unable to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous viral sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


Displaying record number 62253

HXB2 Location  Nef(82-91)   Nef Epitope Map
View variants at this location
Epitope KAAVDLSHFL   Epitope Alignment
Variants
KAAlDLSHFL   susceptible form
KAAlDiSHFL   susceptible form
KgAVDLSHFL   susceptible form
KgAlDLSHFL   susceptible form
Species (MHC/HLA human(C*08)

Variant Details

Showing all: 4 variant(s).


Variant ID.  4365
Epitope Seq.  KAAVDLSHFL
Variant Seq.  KAAlDLSHFL
Mutations V/L
Epitope Location V4L
HXB2 Location V85L
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KAAlDLSHFL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences.


Variant ID.  4366
Epitope Seq.  KAAVDLSHFL
Variant Seq.  KAAlDiSHFL
Mutations V/L L/I
Epitope Location V4L L6I
HXB2 Location V85L L87I
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KAAlDiSHFL was able to elicit a lytic response from Subject 15160's CTL though it was not found in the subject's autologous viral sequences. It is the autologous sequence of the HIV-1 SF2 strain.


Variant ID.  4367
Epitope Seq.  KAAVDLSHFL
Variant Seq.  KgAVDLSHFL
Mutations A/G
Epitope Location A2G
HXB2 Location A83G
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KgAVDLSHFL was able to elicit a lytic response from Subject 15160's CTL and it was found in 4/5 samples of the subject's autologous sequences.


Variant ID.  4368
Epitope Seq.  KAAVDLSHFL
Variant Seq.  KgAlDLSHFL
Mutations A/G V/L
Epitope Location A2G V4L
HXB2 Location A83G V85L
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method Other
Note Variant epitope KgAlDLSHFL was able to elicit a lytic response from Subject 15160's CTL and it was not found in the subject's autologous sequences.

References

Harrer1996b T. Harrer, E. Harrer, S. A. Kalams, P. Barbosa, A. Trocha, R. P. Johnson, T. Elbeik, M. B. Feinberg, S. P. Buchbinder, and B. D. Walker. Cytotoxic T Lymphocytes in Asymptomatic Long-Term Nonprogressing HIV-1 Infection. Breadth and Specificity of the Response and Relation to In Vivo Viral Quasispecies in a Person with Prolonged Infection and Low Viral Load. J. Immunol., 156:2616-2623, 1996. PubMed ID: 8786327. Show all entries for this paper.


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