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Found 19 matching records:

Displaying record number 58244

HXB2 Location  Gag(20-28)   Gag Epitope Map
View variants at this location
Epitope RLRPGGKKK   Epitope Alignment
Variants
{rWEKI}RLRPGGKKK   inferred escape
Species (MHC/HLA human(A*03:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2835
Epitope Seq.  {KWEKI}RLRPGGKKK
Variant Seq.  {rWEKI}RLRPGGKKK
Mutations K/R
Epitope Location K-5R
HXB2 Location K15R
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 3/16 and 1/11 sequences of peptide {KWEKI}RLRPGGKKK varied at 639 and 821 DFOSx to {rWEKI}RLRPGGKKK. Position 15 in the peptide is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58232

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
lSPRTLNAW   inferred escape
xSPRTLNAW   inferred escape
Species (MHC/HLA human(B*57:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2799
Epitope Seq.  ISPRTLNAW
Variant Seq.  lSPRTLNAW
Mutations I/L
Epitope Location I1L
HXB2 Location I147L
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/3 or 2/3 sequences of epitope ISPRTLNAW varied at 350 DFOSx to lSPRTLNAW and xSPRTLNAW, where X = l or s. Position 15 in the epitope is marked as being under selection to vary.


Variant ID.  2800
Epitope Seq.  ISPRTLNAW
Variant Seq.  xSPRTLNAW
Mutations I/X
Epitope Location I1X
HXB2 Location I147X
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/3 or 2/3 sequences of epitope ISPRTLNAW varied at 350 DFOSx to xSPRTLNAW, since x = l or s, and another variant, lSPRTLNAW is found. Position 15 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58236

HXB2 Location  Gag(240-249)   Gag Epitope Map
View variants at this location
Epitope TSTLQEQVGW   Epitope Alignment
Variants
TSTLQEQiGW   inferred escape
TSTLQEQVeW   observed variant
TSnLQEQiaW   observed variant
Species (MHC/HLA human(B*57:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  2806
Epitope Seq.  TSTLQEQVGW
Variant Seq.  TSTLQEQiGW
Mutations V/I
Epitope Location V8I
HXB2 Location V247I
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 8/9 sequences of epitope TSTLQEQVGW varied at 159 DFOSx to ITSTLQEQiGW. Position 115 in the peptide is marked as being under selection to vary.


Variant ID.  2808
Epitope Seq.  TSTLQEQVGW
Variant Seq.  TSTLQEQVeW
Mutations G/E
Epitope Location G9E
HXB2 Location G248E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9 sequences of epitope TSTLQEQVGW varied at 159 DFOSx to TSTLQEQVeW. Position 116 in the peptide is marked as being under selection to vary.


Variant ID.  2809
Epitope Seq.  TSTLQEQVGW
Variant Seq.  TSnLQEQiaW
Mutations T/N V/I G/A
Epitope Location T3N V8I G9A
HXB2 Location T242N V247I G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 8/8 sequences of epitope TSTLQEQVGW varied at 592 DFOSx to TSnLQEQiaW.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58229

HXB2 Location  Gag(240-249)   Gag Epitope Map
View variants at this location
Epitope TSTLQEQIGW   Epitope Alignment
Variants
TSnLQEQIGW   inferred escape
TSTLQEQIeW   inferred escape
Species (MHC/HLA human(B*57:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2796
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSnLQEQIGW
Mutations T/N
Epitope Location T3N
HXB2 Location T242N
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9, 2/9, 1/2 and 3/3 sequences of epitope TSTLQEQIGW varied at 45, 85, 154 and 350 DFOSx to TSnLQEQIGW. Position 110 in the epitope is marked as being under selection to vary.


Variant ID.  2798
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQIeW
Mutations G/E
Epitope Location G9E
HXB2 Location G248E
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/2, 6/9 and 1/2 sequences of epitope TSTLQEQIGW varied at 45, 85 and 154 DFOSx to TSTLQEQIeW. Position 116 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58240

HXB2 Location  Pol(90-98)   Pol Epitope Map
View variants at this location
Epitope EEMNLPGRW   Epitope Alignment
Variants
EdMNLPGRW   inferred escape
Species (MHC/HLA human(B*44:02)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2828
Epitope Seq.  EEMNLPGRW
Variant Seq.  EdMNLPGRW
Mutations E/D
Epitope Location E2D
HXB2 Location E91D
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Epitope EEMNLPGRW varied from 96 DFOSx to EdMNLPGRW.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58246

HXB2 Location  Pol(640-648)   Pol Epitope Map
View variants at this location
Epitope ALQDSGLEV   Epitope Alignment
Variants
ALQDSGvEV   inferred escape
ALQDSGsEV   inferred escape
ALQDSGLEV{Ni}   inferred escape
ALQDSGLEV{Nx}   inferred escape
ALQDSGxEV{Nx}   inferred escape
Species (MHC/HLA human(A*02:01)

Variant Details

Showing all: 5 variant(s).


Variant ID.  2843
Epitope Seq.  ALQDSGLEV
Variant Seq.  ALQDSGvEV
Mutations L/V
Epitope Location L7V
HXB2 Location L646V
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/27 sequences of epitope ALQDSGLEV varied at 552 DFOSx to ALQDSGvEV. Position 491 in the epitope is marked as being under selection to vary.


Variant ID.  2844
Epitope Seq.  ALQDSGLEV
Variant Seq.  ALQDSGsEV
Mutations L/S
Epitope Location L7S
HXB2 Location L646S
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 2/27 and 1/15 sequences of epitope ALQDSGLEV varied at 552 and 718 DFOSx to ALQDSGsEV. Position 491 in the epitope is marked as being under selection to vary.


Variant ID.  2845
Epitope Seq.  ALQDSGLEV{NV}
Variant Seq.  ALQDSGLEV{Ni}
Mutations V/I
Epitope Location V+2I
HXB2 Location V650I
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 12/27 and 12/15 sequences of epitope ALQDSGLEV{NV} varied at 552 and 718 DFOSx to ALQDSGLEV{Ni}. Position 495 in the epitope is marked as being under selection to vary.


Variant ID.  2846
Epitope Seq.  ALQDSGLEV{NV}
Variant Seq.  ALQDSGLEV{Nx}
Mutations V/I
Epitope Location V+2I
HXB2 Location V650I
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/27 (or possibly 13/27) sequences of epitope ALQDSGLEV{NV} varied at 552 DFOSx to ALQDSGLEV{Nx} (as well as possibly 1/15 at 718 DFOSx). Position 495 in the epitope is marked as being under selection to vary.


Variant ID.  2847
Epitope Seq.  ALQDSGLEV{NV}
Variant Seq.  ALQDSGxEV{Nx}
Mutations V/X L/X
Epitope Location V+2X L7X
HXB2 Location V650X L646X
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 2/15 sequences of epitope ALQDSGLEV{NV} varied at 718 DFOSx to ALQDSGxEV{Nx}. Positions 491 and 495 in the epitope are marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58249

HXB2 Location  Vif(113-130)   Vif Epitope Map
View variants at this location
Epitope DCFSESAIRGAILGHIVS   Epitope Alignment
Variants
DCFSESAIRrAILGHIVS   inferred escape
DCFSdSAIRrAILGHIVS   inferred escape
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  2852
Epitope Seq.  DCFSESAIRGAILGHIVS
Variant Seq.  DCFSESAIRrAILGHIVS
Mutations G/R
Epitope Location G10R
HXB2 Location G122R
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Peptide DCFSESAIRGAILGHIVS varied at 101 DFOSx to DCFSESAIRrAILGHIVS. Position 122 in the peptide is marked as being under selection to vary.


Variant ID.  2853
Epitope Seq.  DCFSESAIRGAILGHIVS
Variant Seq.  DCFSdSAIRrAILGHIVS
Mutations G/R E/D
Epitope Location G10R E5D
HXB2 Location G122R E117D
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Peptide DCFSESAIRGAILGHIVS varied from 101 DFOSx onwards to DCFSdSAIRrAILGHIVS. Positions 117 and 122 in the peptide are marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58227

HXB2 Location  Vif(119-127)   Vif Epitope Map
View variants at this location
Epitope AIRKAILGR   Epitope Alignment
Variants
AIRtAILGR   inferred escape
AIReAILGR   inferred escape
Species (MHC/HLA human(A*31:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2790
Epitope Seq.  AIRKAILGR
Variant Seq.  AIRtAILGR
Mutations K/T
Epitope Location K4T
HXB2 Location K122T
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 4/7 sequences of epitope AIRKAlLGR varied at 181 DFOSx to AIRtAlLGR. Position 122 is marked as being selected to vary.


Variant ID.  2791
Epitope Seq.  AIRKAILGR
Variant Seq.  AIReAILGR
Mutations K/E
Epitope Location K4E
HXB2 Location K122E
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 9/12 sequences of epitope AIRKAlLGR varied at 412 DFOSx to AIReAlLGR. Position 122 is marked as being selected to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58228

HXB2 Location  Rev(51-60)   Rev Epitope Map
View variants at this location
Epitope QIRSISERIL   Epitope Alignment
Variants
QIRSISERIf   inferred escape
Species (MHC/HLA human(A*31:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2793
Epitope Seq.  QIRSISERIL
Variant Seq.  QIRSISERIf
Mutations L/F
Epitope Location L10F
HXB2 Location L60F
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9, 1/7 and 1/12 sequences of epitope QIRSISERIL varied at 111, 181 and 412 DFOSx to QIRSISERIf. Position 60 is marked as being selected to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58250

HXB2 Location  gp160(6-20)   gp160 Epitope Map
View variants at this location
Epitope NYQHLWRGGIMLLWRGIM   Epitope Alignment
Variants
NYQHLWRGGIsLLWRGIM   inferred escape
NYQHwWRGGIMLLWRGIM   inferred escape
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  2855
Epitope Seq.  NYQHLWRGGIMLLWRGIM
Variant Seq.  NYQHLWRGGIsLLWRGIM
Mutations M/S
Epitope Location M11S
HXB2 Location M16S
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Peptide NYQHLWRGGIMLLWRGIM varied at 228 DFOSx to NYQHLWRGGIsLLWRGIM. Position 16 in the peptide is marked as being under selection to vary.


Variant ID.  2856
Epitope Seq.  NYQHLWRGGIMLLWRGIM
Variant Seq.  NYQHwWRGGIMLLWRGIM
Mutations L/W
Epitope Location L5W
HXB2 Location L10W
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Peptide NYQHLWRGGIMLLWRGIM varied at 368 DFOSx to NYQHwWRGGIMLLWRGIM. Position 10 in the peptide is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58239

HXB2 Location  gp160(334-351)   gp160 Epitope Map
View variants at this location
Epitope SGEDWNKTLSHVVDKLRE   Epitope Alignment
Variants
SGEDWNKTLSyVVDKLRE   inferred escape
SGEDWNKTLSHVVnKLRE   inferred escape
Species (MHC/HLA human

Variant Details

Showing all: 2 variant(s).


Variant ID.  2820
Epitope Seq.  SGEDWNKTLSHVVDKLRE
Variant Seq.  SGEDWNKTLSyVVDKLRE
Mutations H/Y
Epitope Location H11Y
HXB2 Location H344Y
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/5 and 4/5 sequences of peptide SGEDWNKTLSHVVDKLRE varied at 102 and 592 DFOSx to SGEDWNKTLSyVVDKLRE. Position 344 in the peptide is marked as being under selection to vary.


Variant ID.  2821
Epitope Seq.  SGEDWNKTLSHVVDKLRE
Variant Seq.  SGEDWNKTLSHVVnKLRE
Mutations D/N
Epitope Location D14N
HXB2 Location D347N
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 6/12 sequences of peptide SGEDWNKTLSHVVDKLRE varied at 159 DFOSx to SGEDWNKTLSHVVnKLRE.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58238

HXB2 Location  gp160(352-361)   gp160 Epitope Map
View variants at this location
Epitope QFRNKTIVF   Epitope Alignment
Variants
QFkNKTIVF   inferred escape
QFRNKaIVF   observed variant
QFnNKTIVF   inferred escape
Species (MHC/HLA human(C*04:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  2813
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFkNKTIVF
Mutations R/K
Epitope Location R3K
HXB2 Location R354K
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 11/15, 12/12, 4/5, 10/12 and 3/5 sequences of epitope QFRNKTIVF varied at 14, 32, 102, 159 and 592 DFOSx to QFkNKTIVF. Position 354 in the epitope is marked as being under selection to vary.


Variant ID.  2815
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFRNKaIVF
Mutations T/A
Epitope Location T6A
HXB2 Location T357A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/15 sequences of epitope QFRNKTIVF varied at 14 DFOSx to QFRNKaIVF.


Variant ID.  2817
Epitope Seq.  QFRNKTIVF
Variant Seq.  QFnNKTIVF
Mutations R/N
Epitope Location R3N
HXB2 Location R354N
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/5 and 2/12 sequences of epitope QFRNKTIVF varied at 102 and 159 DFOSx to QFnNKTIVF.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58235

HXB2 Location  gp160(584-592)   gp160 Epitope Map
View variants at this location
Epitope ERYLRDQQL   Epitope Alignment
Variants
ERYLgDQQL   inferred escape
ERYLkDQQL   inferred escape
ERYLsDQQL   inferred escape
ERhLRDQQL   inferred escape
Species (MHC/HLA human(B*14:02)

Variant Details

Showing all: 4 variant(s).


Variant ID.  2801
Epitope Seq.  ERYLRDQQL
Variant Seq.  ERYLgDQQL
Mutations R/G
Epitope Location R5G
HXB2 Location R588G
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/7, 2/9 and 1/9 sequences of epitope ERYLRDQQL varied at 9, 45 and 85 DFOSx to ERYLgDQQL. Position 588 in the epitope is marked as being under selection to vary.


Variant ID.  2802
Epitope Seq.  ERYLRDQQL
Variant Seq.  ERYLkDQQL
Mutations R/K
Epitope Location R5K
HXB2 Location R588K
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9 and 3/9 sequences of epitope ERYLRDQQL varied at 45 and 85 DFOSx to ERYLkDQQL.


Variant ID.  2803
Epitope Seq.  ERYLRDQQL
Variant Seq.  ERYLsDQQL
Mutations R/S
Epitope Location R5S
HXB2 Location R588S
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 2/9, 1/9 and 2/2 sequences of epitope ERYLRDQQL varied at 45, 85 and 350 DFOSx to ERYLsDQQL.


Variant ID.  2805
Epitope Seq.  ERYLRDQQL
Variant Seq.  ERhLRDQQL
Mutations Y/H
Epitope Location Y3H
HXB2 Location Y586H
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/7, 3/9 and 3/9 sequences of epitope ERYLRDQQL varied at 9, 45 and 85 DFOSx to ERhLRDQQL. Position 586 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58237

HXB2 Location  gp160(605-614)   gp160 Epitope Map
View variants at this location
Epitope TTTVPWNVSW   Epitope Alignment
Variants
TTTVPWNtSW   inferred escape
TTTVPWNsSW   inferred escape
Species (MHC/HLA human(B*57:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2810
Epitope Seq.  TTTVPWNVSW
Variant Seq.  TTTVPWNtSW
Mutations V/T
Epitope Location V8T
HXB2 Location V612T
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 3/5 sequences of epitope TTTVPWNVSW varied at 592 DFOSx to TTTVPWNtSW. Position 612 in the epitope is marked as being under selection to vary.


Variant ID.  2812
Epitope Seq.  TTTVPWNVSW
Variant Seq.  TTTVPWNsSW
Mutations V/S
Epitope Location V8S
HXB2 Location V612S
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 3/5 sequences of epitope TTTVPWNVSW varied at 592 DFOSx to TTTVPWNsSW. Position 612 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58226

HXB2 Location  gp160(830-847)   gp160 Epitope Map
View variants at this location
Epitope IEVVQRACRAILHIPRRI   Epitope Alignment
Variants
IEVVQRACRAIfHIPRRI   observed variant
IEiVQRACRAILHIPRRI   observed variant
IEVVQRACRAILHIPRkI   observed variant
IEVVQRACRAIcHIPRRI   observed variant
IEVVQRACRAIrHIPRRI   observed variant
Species (MHC/HLA human

Variant Details

Showing all: 5 variant(s).


Variant ID.  2784
Epitope Seq.  IEVVQRACRAILHIPRRI
Variant Seq.  IEVVQRACRAIfHIPRRI
Mutations L/F
Epitope Location L12F
HXB2 Location L841F
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9 sequences of peptide IEVVQRACRAILHIPRRI varied at 111 DFOSx to IEVVQRACRAIfHIPRRI.


Variant ID.  2785
Epitope Seq.  IEVVQRACRAILHIPRRI
Variant Seq.  IEiVQRACRAILHIPRRI
Mutations V/I
Epitope Location V3I
HXB2 Location V832I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/9 sequences of peptide IEVVQRACRAILHIPRRI varied at 111 DFOSx to IEiVQRACRAILHIPRRI.


Variant ID.  2786
Epitope Seq.  IEVVQRACRAILHIPRRI
Variant Seq.  IEVVQRACRAILHIPRkI
Mutations R/K
Epitope Location R17K
HXB2 Location R846K
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/7 sequences of peptide IEVVQRACRAILHIPRRI varied at 181 DFOSx to IEVVQRACRAILHIPRkI.


Variant ID.  2787
Epitope Seq.  IEVVQRACRAILHIPRRI
Variant Seq.  IEVVQRACRAIcHIPRRI
Mutations L/C
Epitope Location L12C
HXB2 Location L841C
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/12 sequences of peptide IEVVQRACRAILHIPRRI varied at 412 DFOSx to IEVVQRACRAIcHIPRRI. Position 841 in the peptide is marked as being under selection to vary.


Variant ID.  2788
Epitope Seq.  IEVVQRACRAILHIPRRI
Variant Seq.  IEVVQRACRAIrHIPRRI
Mutations L/R
Epitope Location L12R
HXB2 Location L841R
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 1/12 sequences of peptide IEVVQRACRAILHIPRRI varied at 412 DFOSx to IEVVQRACRAIrHIPRRI. Position 841 in the peptide is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58242

HXB2 Location  Nef(73-82)   Nef Epitope Map
View variants at this location
Epitope QVPLRPMTYK   Epitope Alignment
Variants
QVPLRPMTYK{gA}   inferred escape
QVPLRPMTfK{gA}   inferred escape
Species (MHC/HLA human(A*03:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2837
Epitope Seq.  QVPLRPMTYK{AA}
Variant Seq.  QVPLRPMTYK{gA}
Mutations A/G
Epitope Location A+1G
HXB2 Location A83G
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 8/14 sequences of peptide QVPLRPMTYK{AA} varied at 639 DFOSx to QVPLRPMTYK{gA}. Position 83 in the peptide is marked as being under selection to vary.


Variant ID.  2839
Epitope Seq.  QVPLRPMTYK{AA}
Variant Seq.  QVPLRPMTfK{gA}
Mutations A/G Y/F
Epitope Location A+1G Y9F
HXB2 Location A83G Y81F
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 5/14 and 12/13 sequences of peptide QVPLRPMTYK{AA} varied at 639 and 821 DFOSx to QVPLRPMTfK{gA}. Positions 81 and 83 in the peptide are marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58245

HXB2 Location  Nef(92-100)   Nef Epitope Map
View variants at this location
Epitope KEKGGLEGL   Epitope Alignment
Variants
KEKGGLEGm   inferred escape
Species (MHC/HLA human(B*40:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2842
Epitope Seq.  KEKGGLEGL
Variant Seq.  KEKGGLEGm
Mutations L/M
Epitope Location L9M
HXB2 Location L100M
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note 16/21 and 8/10 sequences of epitope KEKGGLEGL varied at 552 and 718 DFOSx to KEKGGLEGm. Position 100 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58248

HXB2 Location  Nef(181-189)   Nef Epitope Map
View variants at this location
Epitope LEWRFDITL   Epitope Alignment
Variants
LaWRFDITL   inferred escape
LqWRFDITL   inferred escape
LpWRFDITL   inferred escape
LvWRFDITL   inferred escape
Species (MHC/HLA human(A*02:01)

Variant Details

Showing all: 4 variant(s).


Variant ID.  2848
Epitope Seq.  LEWRFDITL
Variant Seq.  LaWRFDITL
Mutations E/A
Epitope Location E2A
HXB2 Location E182A
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Epitope LEWRFDITL varied at 228 and 368 DFOSx to LaWRFDITL. Position 182 in the epitope is marked as being under selection to vary.


Variant ID.  2849
Epitope Seq.  LEWRFDITL
Variant Seq.  LqWRFDITL
Mutations E/Q
Epitope Location E2Q
HXB2 Location E182Q
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Epitope LEWRFDITL varied at 228, 552 and 718 DFOSx to LqWRFDITL. Position 182 in the epitope is marked as being under selection to vary.


Variant ID.  2850
Epitope Seq.  LEWRFDITL
Variant Seq.  LpWRFDITL
Mutations E/P
Epitope Location E2P
HXB2 Location E182P
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Epitope LEWRFDITL varied at 228 DFOSx to LpWRFDITL. Position 182 in the epitope is marked as being under selection to vary.


Variant ID.  2851
Epitope Seq.  LEWRFDITL
Variant Seq.  LvWRFDITL
Mutations E/P
Epitope Location E2P
HXB2 Location E182P
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Epitope LEWRFDITL varied at 552 and 718 DFOSx to LvWRFDITL. Position 182 in the epitope is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 58241

HXB2 Location  Nef(185-202)   Nef Epitope Map
View variants at this location
Epitope FDSRLAFHHIARELHPEY   Epitope Alignment
Variants
FDSlLAFHHIARELHPEY   inferred escape
Species (MHC/HLA human(A*02:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2840
Epitope Seq.  FDSRLAFHHIARELHPEY
Variant Seq.  FDSlLAFHHIARELHPEY
Mutations R/L
Epitope Location R4L
HXB2 Location R188L
Mutation Type IE: inferred escape
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Peptide FDSRLAFHHIARELHPEY varied from 183 DFOSx onwards to FDSlLAFHHIARELHPEY. Position 188 in the peptide is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


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