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Found 3 matching records:

Displaying record number 57412

HXB2 Location Gag(146-156) Gag Epitope Map
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AISPRTLNAWV

`pISPRTLNAWV`		observed variant
`plSPRTLNAWV`		observed variant
`pISaRTLNAWV`		observed variant
`AlSPRTLNAWV`		observed variant

Epitope Name IW9

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 4 variant(s).

Variant ID.	`2353`
Epitope Seq.	`AISPRTLNAWV`
Variant Seq.	`pISPRTLNAWV`
Mutations	A/P
Epitope Location	A1P
HXB2 Location	A146P
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5703 positive patient with low viral load carried this variant from month 6 after enrollment.

Variant ID.	`2355`
Epitope Seq.	`AISPRTLNAWV`
Variant Seq.	`plSPRTLNAWV`
Mutations	A/P I/L
Epitope Location	A1P I2L
HXB2 Location	A146P I147L
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5703 positive patient with increased viral load carried this variant from month 10 after enrollment onwards.

Variant ID.	`2356`
Epitope Seq.	`AISPRTLNAWV`
Variant Seq.	`pISaRTLNAWV`
Mutations	A/P P/A
Epitope Location	A1P P4A
HXB2 Location	A146P P149A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5701 positive patient with increased viral load carried this variant from enrollment onwards.

Variant ID.	`2357`
Epitope Seq.	`AISPRTLNAWV`
Variant Seq.	`AlSPRTLNAWV`
Mutations	I/L
Epitope Location	I2L
HXB2 Location	I147L
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B5701 positive patient with low viral load carried this variant, AlSPRTLNAWV, at month 28 after enrollment; One HLA-B5702 positive patient with low viral load carried it at month 13; and one HLA-B*5703 positive patient with increased viral load carried it from 7 months post-enrollment on.

References

Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.

Displaying record number 57382

HXB2 Location Gag(240-249) Gag Epitope Map
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Epitope

TSTLQEQIGW

Epitope Alignment

Variants

`TSTLQEQIaW`		observed variant
`TSTLQdQvaW`		observed variant
`TSnLQEQIaW`		observed variant
`TSTLQEQItW`		observed variant
`TSTLQEQIeW`		observed variant
`TSTLeEQIdW`		observed variant
`TSnLQEQvaW`		observed variant
`TSTLQEQIdW`		observed variant
`TSTLQEQInW`		observed variant
`TSnLQEQInW`		observed variant

Epitope Name TW10

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 10 variant(s).

Variant ID.	`2343`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQEQIaW`
Mutations	G/A
Epitope Location	G9A
HXB2 Location	G248A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Note	One HLA-B*5703 positive patient with low viral load carried this mutation at enrollment.

Variant ID.	`2344`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQdQvaW`
Mutations	E/D I/V G/A
Epitope Location	E6D I8V G9A
HXB2 Location	E245D I247V G248A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5701 positive patient with low viral load carried this mutation at enrollment.

Variant ID.	`2345`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSnLQEQIaW`
Mutations	T/N G/A
Epitope Location	T3N G9A
HXB2 Location	T242N G248A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B5703 positive patient with low viral load carried this mutation by month 6; one HLA-B5701 positive patient with low viral load carried it by month 28.

Variant ID.	`2346`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQEQItW`
Mutations	G/T
Epitope Location	G9T
HXB2 Location	G248T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5703 positive patient with low viral load carried this mutation at enrollment.

Variant ID.	`2347`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQEQIeW`
Mutations	G/E
Epitope Location	G9E
HXB2 Location	G248E
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5702 positive patient with low viral load carried this mutation at enrollment.

Variant ID.	`2348`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLeEQIdW`
Mutations	Q/E G/D
Epitope Location	Q5E G9D
HXB2 Location	Q244E G248D
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5702 positive patient with low viral load carried this mutation at month 13 after enrollment.

Variant ID.	`2349`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSnLQEQvaW`
Mutations	T/N I/V G/A
Epitope Location	T3N I8V G9A
HXB2 Location	T242N I247V G248A
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5701 positive patient with low viral load carried this variant from month 10 onwards.

Variant ID.	`2350`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQEQIdW`
Mutations	G/D
Epitope Location	G9D
HXB2 Location	G248D
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B5702 positive patient with low viral load carried this mutation a month after enrollment; one HLA-B5701 positive patient with increased viral load also carried this variant from enrollment on.

Variant ID.	`2351`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSTLQEQInW`
Mutations	G/N
Epitope Location	G9N
HXB2 Location	G248N
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5703 positive patient with increased viral load carried this mutation at enrollment.

Variant ID.	`2352`
Epitope Seq.	`TSTLQEQIGW`
Variant Seq.	`TSnLQEQInW`
Mutations	T/N G/N
Epitope Location	T3N G9N
HXB2 Location	T242N G248N
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B*5703 positive patient carried this mutation from enrollment on.

References

Displaying record number 57413

HXB2 Location Gag(308-316) Gag Epitope Map
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Epitope

QASQEVKNW

Epitope Alignment

Variants

`QAStEVKNW`		observed variant
`QASQdVKNW`		observed variant

Epitope Name QW9

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 2 variant(s).

Variant ID.	`2358`
Epitope Seq.	`QASQEVKNW`
Variant Seq.	`QAStEVKNW`
Mutations	Q/T
Epitope Location	Q4T
HXB2 Location	Q311T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	Two patients, both with low viral load, positive for HLAs B5703 and B5701 respectively, carried variant QAStEVKNW from enrollment on.

Variant ID.	`2359`
Epitope Seq.	`QASQEVKNW`
Variant Seq.	`QASQdVKNW`
Mutations	E/D
Epitope Location	E5D
HXB2 Location	E312D
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	One HLA-B5702 positive patient with low viral carried this variant from enrollment on; one HLA-B5701 positive patient with increased viremia also carried it from enrollment.