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Found 3 matching records:

Displaying record number 57412

HXB2 Location  Gag(146-156)   Gag Epitope Map
View variants at this location
Epitope AISPRTLNAWV   Epitope Alignment
Variants
pISPRTLNAWV   observed variant
plSPRTLNAWV   observed variant
pISaRTLNAWV   observed variant
AlSPRTLNAWV   observed variant
Epitope Name IW9
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 4 variant(s).


Variant ID.  2353
Epitope Seq.  AISPRTLNAWV
Variant Seq.  pISPRTLNAWV
Mutations A/P
Epitope Location A1P
HXB2 Location A146P
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient with low viral load carried this variant from month 6 after enrollment.


Variant ID.  2355
Epitope Seq.  AISPRTLNAWV
Variant Seq.  plSPRTLNAWV
Mutations A/P I/L
Epitope Location A1P I2L
HXB2 Location A146P I147L
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient with increased viral load carried this variant from month 10 after enrollment onwards.


Variant ID.  2356
Epitope Seq.  AISPRTLNAWV
Variant Seq.  pISaRTLNAWV
Mutations A/P P/A
Epitope Location A1P P4A
HXB2 Location A146P P149A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5701 positive patient with increased viral load carried this variant from enrollment onwards.


Variant ID.  2357
Epitope Seq.  AISPRTLNAWV
Variant Seq.  AlSPRTLNAWV
Mutations I/L
Epitope Location I2L
HXB2 Location I147L
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5701 positive patient with low viral load carried this variant, AlSPRTLNAWV, at month 28 after enrollment; One HLA-B*5702 positive patient with low viral load carried it at month 13; and one HLA-B*5703 positive patient with increased viral load carried it from 7 months post-enrollment on.

References

Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.


Displaying record number 57382

HXB2 Location  Gag(240-249)   Gag Epitope Map
View variants at this location
Epitope TSTLQEQIGW   Epitope Alignment
Variants
TSTLQEQIaW   observed variant
TSTLQdQvaW   observed variant
TSnLQEQIaW   observed variant
TSTLQEQItW   observed variant
TSTLQEQIeW   observed variant
TSTLeEQIdW   observed variant
TSnLQEQvaW   observed variant
TSTLQEQIdW   observed variant
TSTLQEQInW   observed variant
TSnLQEQInW   observed variant
Epitope Name TW10
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 10 variant(s).


Variant ID.  2343
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQIaW
Mutations G/A
Epitope Location G9A
HXB2 Location G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Note One HLA-B*5703 positive patient with low viral load carried this mutation at enrollment.


Variant ID.  2344
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQdQvaW
Mutations E/D I/V G/A
Epitope Location E6D I8V G9A
HXB2 Location E245D I247V G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5701 positive patient with low viral load carried this mutation at enrollment.


Variant ID.  2345
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSnLQEQIaW
Mutations T/N G/A
Epitope Location T3N G9A
HXB2 Location T242N G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient with low viral load carried this mutation by month 6; one HLA-B*5701 positive patient with low viral load carried it by month 28.


Variant ID.  2346
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQItW
Mutations G/T
Epitope Location G9T
HXB2 Location G248T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient with low viral load carried this mutation at enrollment.


Variant ID.  2347
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQIeW
Mutations G/E
Epitope Location G9E
HXB2 Location G248E
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5702 positive patient with low viral load carried this mutation at enrollment.


Variant ID.  2348
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLeEQIdW
Mutations Q/E G/D
Epitope Location Q5E G9D
HXB2 Location Q244E G248D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5702 positive patient with low viral load carried this mutation at month 13 after enrollment.


Variant ID.  2349
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSnLQEQvaW
Mutations T/N I/V G/A
Epitope Location T3N I8V G9A
HXB2 Location T242N I247V G248A
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5701 positive patient with low viral load carried this variant from month 10 onwards.


Variant ID.  2350
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQIdW
Mutations G/D
Epitope Location G9D
HXB2 Location G248D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5702 positive patient with low viral load carried this mutation a month after enrollment; one HLA-B*5701 positive patient with increased viral load also carried this variant from enrollment on.


Variant ID.  2351
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSTLQEQInW
Mutations G/N
Epitope Location G9N
HXB2 Location G248N
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient with increased viral load carried this mutation at enrollment.


Variant ID.  2352
Epitope Seq.  TSTLQEQIGW
Variant Seq.  TSnLQEQInW
Mutations T/N G/N
Epitope Location T3N G9N
HXB2 Location T242N G248N
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5703 positive patient carried this mutation from enrollment on.

References

Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.


Displaying record number 57413

HXB2 Location  Gag(308-316)   Gag Epitope Map
View variants at this location
Epitope QASQEVKNW   Epitope Alignment
Variants
QAStEVKNW   observed variant
QASQdVKNW   observed variant
Epitope Name QW9
Species (MHC/HLA human(B*57)

Variant Details

Showing all: 2 variant(s).


Variant ID.  2358
Epitope Seq.  QASQEVKNW
Variant Seq.  QAStEVKNW
Mutations Q/T
Epitope Location Q4T
HXB2 Location Q311T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Two patients, both with low viral load, positive for HLAs B*5703 and B*5701 respectively, carried variant QAStEVKNW from enrollment on.


Variant ID.  2359
Epitope Seq.  QASQEVKNW
Variant Seq.  QASQdVKNW
Mutations E/D
Epitope Location E5D
HXB2 Location E312D
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note One HLA-B*5702 positive patient with low viral carried this variant from enrollment on; one HLA-B*5701 positive patient with increased viremia also carried it from enrollment.

References

Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.


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