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Found 7 matching records:

Displaying record number 61674

HXB2 Location  Gag(146-155)   Gag Epitope Map
View variants at this location
Epitope AISPRTLNAW   Epitope Alignment
Variants
pISPRTLNAW   HLA association
AlSPRTLNAW   HLA association
AmSPRTLNAW   HLA association
Epitope Name Gag-IW9
Species (MHC/HLA human(B*57:02, B*57:03, B*58:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  4057
Epitope Seq.  AISPRTLNAW
Variant Seq.  pISPRTLNAW
Mutations A/P
Epitope Location A1P
HXB2 Location A146P
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, pISPRTLNAW, was associated more strongly with HLAs-B*5702 and B*5703 than with HLA-B*5801.


Variant ID.  4058
Epitope Seq.  AISPRTLNAW
Variant Seq.  AlSPRTLNAW
Mutations I/L
Epitope Location I2L
HXB2 Location I147L
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, AlSPRTLNAW, was associated more strongly with HLAs-B*5702 and B*5703 than with HLA-B*5801.


Variant ID.  4059
Epitope Seq.  AISPRTLNAW
Variant Seq.  AmSPRTLNAW
Mutations I/M
Epitope Location I2M
HXB2 Location I147M
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, AmSPRTLNAW, was associated more strongly with HLA-B*5703 than with HLA-B*5801.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61675

HXB2 Location  Gag(161-172)   Gag Epitope Map
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Epitope EKAFSPEVIPMF   Epitope Alignment
Variants
dKAFSPEVIPMF   HLA association
EKsFSPEVIPMF   HLA association
EKAFnPEVIPMF   HLA association
EKgFSPEVIPMF   HLA association
EKAFkPEVIPMF   HLA association
Epitope Name Gag-KF11
Species (MHC/HLA human(B*57:03, B*58:01)

Variant Details

Showing all: 5 variant(s).


Variant ID.  4060
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  dKAFSPEVIPMF
Mutations E/D
Epitope Location E1D
HXB2 Location E161D
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, dKAFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Variant ID.  4061
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKsFSPEVIPMF
Mutations A/S
Epitope Location A3S
HXB2 Location A163S
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKsFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Variant ID.  4062
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKAFnPEVIPMF
Mutations S/N
Epitope Location S5N
HXB2 Location S165N
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKAFnPEVIPMF, was associated more strongly with HLA-B*5703 than with HLAs-B*5801 and B*5702.


Variant ID.  4063
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKgFSPEVIPMF
Mutations A/G
Epitope Location A3G
HXB2 Location A163G
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKgFSPEVIPMF, was associated more strongly with HLA-B*5703 than with HLAs-B*5801 and B*5702.


Variant ID.  4064
Epitope Seq.  EKAFSPEVIPMF
Variant Seq.  EKAFkPEVIPMF
Mutations S/K
Epitope Location S5K
HXB2 Location S165K
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Computer prediction
Note HLA-associated escape, EKAFkPEVIPMF, was associated most strongly with HLA-B*5703.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61676

HXB2 Location  Gag(240-249)   Gag Epitope Map
View variants at this location
Epitope TSTLQEQIAW   Epitope Alignment
Variants
TSTLQEQvAW   HLA association
TSnLQEQIAW   HLA association
TSTLQEQmAW   HLA association
Epitope Name Gag-TW10
Species (MHC/HLA human(B*57:03, B*58:01)

Variant Details

Showing all: 3 variant(s).


Variant ID.  4065
Epitope Seq.  TSTLQEQIAW
Variant Seq.  TSTLQEQvAW
Mutations I/V
Epitope Location I8V
HXB2 Location I168V
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, TSTLQEQvAW, was associated more strongly with HLA-B*5703 than with HLA-B*5801.


Variant ID.  4066
Epitope Seq.  TSTLQEQIAW
Variant Seq.  TSnLQEQIAW
Mutations T/N
Epitope Location T3N
HXB2 Location T163N
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, TSnLQEQIAW, was associated all three HLAs-B*5702, B*5703, and B*5801.


Variant ID.  4067
Epitope Seq.  TSTLQEQIAW
Variant Seq.  TSTLQEQmAW
Mutations I/M
Epitope Location I8M
HXB2 Location I168M
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, TSTLQEQmAW, was associated more strongly with HLA-B*5702 than with HLA-B*5801.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61677

HXB2 Location  Gag(308-316)   Gag Epitope Map
View variants at this location
Epitope QATQDVKNW   Epitope Alignment
Variants
QsTQDVKNW   HLA association
QAsQDVKNW   HLA association
Epitope Name Gag-QW9
Species (MHC/HLA human(B*58:01)

Variant Details

Showing all: 2 variant(s).


Variant ID.  4068
Epitope Seq.  QATQDVKNW
Variant Seq.  QsTQDVKNW
Mutations A/S
Epitope Location A2S
HXB2 Location A309S
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, QsTQDVKNW, was associated with HLA-B*5801.


Variant ID.  4069
Epitope Seq.  QATQDVKNW
Variant Seq.  QAsQDVKNW
Mutations T/S
Epitope Location T3S
HXB2 Location T310S
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, QAsQDVKNW, was associated more strongly with HLA-B*5801 than with HLAs-B*5702 or -5703.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61678

HXB2 Location  Pol(530-538)   Pol Epitope Map
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Epitope IAMESIVIW   Epitope Alignment
Variants
vAMESIVIW   HLA association
IAqESIVIW   HLA association
IAtESIVIW   HLA association
IAMEaIVIW   HLA association
Epitope Name RT-IW9
Species (MHC/HLA human(B*58:01)

Variant Details

Showing all: 4 variant(s).


Variant ID.  4070
Epitope Seq.  IAMESIVIW
Variant Seq.  vAMESIVIW
Mutations I/V
Epitope Location I1V
HXB2 Location I530V
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, vAMESIVIW, was more significantly associated with HLA-B*5801 than with B*5703.


Variant ID.  4071
Epitope Seq.  IAMESIVIW
Variant Seq.  IAqESIVIW
Mutations M/Q
Epitope Location M3Q
HXB2 Location M532Q
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, IAqESIVIW, was more significantly associated with HLA-B*5801 than with B*5703.


Variant ID.  4072
Epitope Seq.  IAMESIVIW
Variant Seq.  IAtESIVIW
Mutations M/T
Epitope Location M3T
HXB2 Location M532T
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, IAtESIVIW, was associated with HLA-B*5801.


Variant ID.  4073
Epitope Seq.  IAMESIVIW
Variant Seq.  IAMEaIVIW
Mutations S/A
Epitope Location S5A
HXB2 Location S534A
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, IAMEaIVIW, was associated with HLA-B*5801.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61679

HXB2 Location  Nef(82-91)   Nef Epitope Map
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Epitope KAAFDLSFFL   Epitope Alignment
Variants
KgAFDLSFFL   HLA association
Epitope Name Nef-KL10
Species (MHC/HLA human(B*57:02, B*57:03, B*58:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  4074
Epitope Seq.  KAAFDLSFFL
Variant Seq.  KgAFDLSFFL
Mutations A/G
Epitope Location A2G
HXB2 Location A83G
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, KgAFDLSFFL, was more significantly associated with HLA-B*5801 than with B*5703.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 61680

HXB2 Location  Nef(116-124)   Nef Epitope Map
View variants at this location
Epitope HTQGFFPDW   Epitope Alignment
Variants
nTQGFFPDW   HLA association
Epitope Name Nef-HW9
Species (MHC/HLA human(B*35:01, B*53:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  4075
Epitope Seq.  HTQGFFPDW
Variant Seq.  nTQGFFPDW
Mutations H/N
Epitope Location H1N
HXB2 Location H116N
Mutation Type A: HLA association
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy
Note HLA-associated escape, nTQGFFPDW, was more significantly associated with HLA-B*5703 than with B*5801.

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


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