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Found 8 matching records:

Displaying record number 62276

HXB2 Location Gag(146-155) Gag Epitope Map
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AISPRTLNAW

`plSPRTLNAW`		escape documented in this paper
`AlSPRTLNAW`		escape documented in this paper
`pISPRTLNAW`		escape documented in this paper

Epitope Name AW10, IW9

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`4382`
Epitope Seq.	`AISPRTLNAW`
Variant Seq.	`plSPRTLNAW`
Mutations	A/P I/L
Epitope Location	A1P I2L
HXB2 Location	A146P I147L
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Double mutation, plSPRTLNAW, was seen at all times in patient2.

Variant ID.	`4383`
Epitope Seq.	`AISPRTLNAW`
Variant Seq.	`AlSPRTLNAW`
Mutations	I/L
Epitope Location	I2L
HXB2 Location	I147L
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation AlSPRTLNAW, was seen in patient4 before 30/47 months post infection.

Variant ID.	`4384`
Epitope Seq.	`AISPRTLNAW`
Variant Seq.	`pISPRTLNAW`
Mutations	A/P
Epitope Location	A1P
HXB2 Location	A146P
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation pISPRTLNAW, was seen in patients 3 and 4 30/47 months post infection.

References

Bansal2007 Anju Bansal, Ling Yue, Joan Conway, Karina Yusim, Jianming Tang, John Kappes, Richard A. Kaslow, Craig M. Wilson, and Paul A. Goepfert. Immunological Control of Chronic HIV-1 Infection: HLA-Mediated Immune Function and Viral Evolution in Adolescents. AIDS, 21(18):2387-2397, 30 Nov 2007. PubMed ID: 18025875. Show all entries for this paper.

Displaying record number 62280

HXB2 Location Gag(180-188) Gag Epitope Map
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Epitope

TPQDLNTML

Epitope Alignment

Variants

TPhDLNTML observed variant

Epitope Name Gag-TL9

Species (MHC/HLA) human(B*35, B*53)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`4392`
Epitope Seq.	`TPQDLNTML`
Variant Seq.	`TPhDLNTML`
Mutations	Q/H
Epitope Location	Q3H
HXB2 Location	Q182H
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation TPhDLNTML was seen in patient 7 after 30 or 47 months.

References

Displaying record number 62277

HXB2 Location Gag(240-250) Gag Epitope Map
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Epitope

TSTLQEQIGWM

Epitope Alignment

Variants

`TSnLQEQIGWM`		escape documented in this paper
`TSnLQEQItWM`		escape documented in this paper
`TSTpQEQIaWM`		escape documented in this paper

Epitope Name TW10

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`4385`
Epitope Seq.	`TSTLQEQIGWM`
Variant Seq.	`TSnLQEQIGWM`
Mutations	T/N
Epitope Location	T3N
HXB2 Location	T242N
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Escape TSnLQEQIGW was seen in patient2 before 30/47 months.

Variant ID.	`4386`
Epitope Seq.	`TSTLQEQIGWM`
Variant Seq.	`TSnLQEQItWM`
Mutations	T/N G/T
Epitope Location	T3N G9T
HXB2 Location	T242N G248T
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Escape TSnLQEQIaW was seen in patient4 at all times sampled.

Variant ID.	`4387`
Epitope Seq.	`TSTLQEQIGWM`
Variant Seq.	`TSTpQEQIaWM`
Mutations	L/P G/A
Epitope Location	L4P G9A
HXB2 Location	L243P G248A
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Escape TSTpQEQIaWM was seen in patient3 after 30/47 months.

References

Displaying record number 62275

HXB2 Location Gag(308-316) Gag Epitope Map
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Epitope

QASQEVKNW

Epitope Alignment

Variants

`QASQdVKNW`		observed variant
`QASQdVKsW`		observed variant
`QAtQEVKNW`		observed variant

Epitope Name QW9

Species (MHC/HLA) human(B*35, B*57)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`4379`
Epitope Seq.	`QASQEVKNW`
Variant Seq.	`QASQdVKNW`
Mutations	E/D
Epitope Location	E5D
HXB2 Location	E312D
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	The E to D change in QW9 is a common non-selection-driven mutation seen in B57 and B35/43 carriers. It was seen in patients 3 and 4 at all times and patients 2, 5 after 30/47 months, while it was observed in patient 9 only before 30/47 months.

Variant ID.	`4380`
Epitope Seq.	`QASQEVKNW`
Variant Seq.	`QASQdVKsW`
Mutations	E/D N/S
Epitope Location	E5D N8S
HXB2 Location	E312D N315S
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	The QW9 mutation, QASQdVKsW, was seen in patient 11 at all times sampled.

Variant ID.	`4381`
Epitope Seq.	`QASQEVKNW`
Variant Seq.	`QAtQEVKNW`
Mutations	S/T
Epitope Location	S3T
HXB2 Location	S310T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	The QW9 mutation, QAtQEVKNW, was seen in patient7 at all times sampled, but in patient10 after 30/47 months' infection.

References

Displaying record number 62281

HXB2 Location Nef(74-81) Nef Epitope Map
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Epitope

VPLRPMTY

Epitope Alignment

Variants

`VPLRPMTf`		escape documented in this paper
`lPLRPMTY`		observed variant
`VPLRPiTY`		observed variant
`VPLRPMTt`		observed variant
`VPLRPMnY`		observed variant

Epitope Name VY8

Species (MHC/HLA) human(B*35, B*53)

Variant Details

Showing all: 5 variant(s).

Variant ID.	`4393`
Epitope Seq.	`VPLRPMTY`
Variant Seq.	`VPLRPMTf`
Mutations	Y/F
Epitope Location	Y8F
HXB2 Location	Y81F
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Escape Y81F, VPLRPMTf, was seen in patient8 after 30/47 months.

Variant ID.	`4394`
Epitope Seq.	`VPLRPMTY`
Variant Seq.	`lPLRPMTY`
Mutations	V/L
Epitope Location	V1L
HXB2 Location	V74L
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation lPLRPMTY, was seen in patient8 before 30/47 months.

Variant ID.	`4395`
Epitope Seq.	`VPLRPMTY`
Variant Seq.	`VPLRPiTY`
Mutations	M/I
Epitope Location	M6I
HXB2 Location	M79I
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation VPLRPiTY, was seen in patient6 before 30/47 months and patient10 after 30/47 months.

Variant ID.	`4396`
Epitope Seq.	`VPLRPMTY`
Variant Seq.	`VPLRPMTt`
Mutations	Y/T
Epitope Location	Y8T
HXB2 Location	Y81T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation VPLRPMTt, was seen in patient7 at all times sampled.

Variant ID.	`4397`
Epitope Seq.	`VPLRPMTY`
Variant Seq.	`VPLRPMnY`
Mutations	T/N
Epitope Location	T7N
HXB2 Location	T80N
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation VPLRPMnY, was seen in patient6 after 30/47 months.

References

Displaying record number 62278

HXB2 Location Nef(82-90) Nef Epitope Map
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Epitope

KAAVDLSHF

Epitope Alignment

Variants

`KAAVDiSHF`		observed variant
`KAAVnLSHF`		observed variant
`KgAlDLSHF`		observed variant

Epitope Name KF9

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`4388`
Epitope Seq.	`KAAVDLSHF`
Variant Seq.	`KAAVDiSHF`
Mutations	L/I
Epitope Location	L6I
HXB2 Location	L87I
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	This mutation, KAAVDiSHF, was seen in patient1 at all times sampled and in patient3 before 30/47 months.

Variant ID.	`4389`
Epitope Seq.	`KAAVDLSHF`
Variant Seq.	`KAAVnLSHF`
Mutations	D/N
Epitope Location	D5N
HXB2 Location	D86N
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	This mutation, KAAVnLSHF, was seen in patient2 before 30/47 months.

Variant ID.	`4390`
Epitope Seq.	`KAAVDLSHF`
Variant Seq.	`KgAlDLSHF`
Mutations	A/G V/L
Epitope Location	A2G V4L
HXB2 Location	A83G V85L
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	This mutation, KgAlDLSHF, was seen in patient4 at all times sampled and in patient3 after 30/47 months.

References

Displaying record number 62279

HXB2 Location Nef(116-125) Nef Epitope Map
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Epitope

HTQGYFPDWQ

Epitope Alignment

Variants

nTQGYFPDWQ escape documented in this paper

Epitope Name Nef-HQ10

Species (MHC/HLA) human(B*57)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`4391`
Epitope Seq.	`HTQGYFPDWQ`
Variant Seq.	`nTQGYFPDWQ`
Mutations	H/N
Epitope Location	H1N
HXB2 Location	H116N
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Mutation nTQGYFPDWQ was seen n patient 4 at all times sampled and in pateitn3 after 30/47 months.

References

Displaying record number 62274

HXB2 Location Nef(135-143) Nef Epitope Map
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Epitope

YPLTFGWCY

Epitope Alignment

Variants

`fPLTFGWCY`		observed variant
`YPLTlGWCY`		escape documented in this paper
`YPLcFGWCY`		escape documented in this paper

Epitope Name YY9

Species (MHC/HLA) human(B*35)

Variant Details

Showing all: 3 variant(s).

Variant ID.	`4376`
Epitope Seq.	`YPLTFGWCY`
Variant Seq.	`fPLTFGWCY`
Mutations	Y/F
Epitope Location	Y1F
HXB2 Location	Y135F
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Longitudinal study, Other
Note	Y135F was a mutation observed in B35/B53-Subjects 5 (before 30 months) and 6 (after 30/47 months).

Variant ID.	`4377`
Epitope Seq.	`YPLTFGWCY`
Variant Seq.	`YPLTlGWCY`
Mutations	F/L
Epitope Location	F5L
HXB2 Location	F139L
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Longitudinal study, Other
Note	F139L was a mutation observed in B35/B53-Subject7 that tested with poor recognition by EliSpot. It was observed in patient5 earlier than 30 months post-infection and patient6, after 30/47 months.

Variant ID.	`4378`
Epitope Seq.	`YPLTFGWCY`
Variant Seq.	`YPLcFGWCY`
Mutations	T/C
Epitope Location	T4C
HXB2 Location	T138C
Mutation Type	E: escape documented in this paper
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Longitudinal study, Other
Note	T138C was a mutation observed in B35/B53-Subjects 9 and 11 (after 30/47 months) that tested with poor recognition by EliSpot.