HIV molecular immunology database

 

Patient Detail

Patient Code NIH45 (Donor 45, NIAID 45)
Patient Sex Male
Risk Factor
Infection Country US
Infection City
Infection Year
HLA Type
Patient Ethnicity African-American
Progression Long Term Non-Progressor (LTNP)
Species human
Patient Note Infected with Clade B, yet displayed neutralization activity against all genetic subtypes of HIV-1; diagnosis in 1990; sampled in 2006 (for NIH45-46 and VRC01); patient info from Zhou2013a [PMID 23911655]. Donor 45 is the source of antibody VRC03 and was studied extensively for VH chain evolution in Wu2011 [PMID: 21835983].
CTL CD8+ Records
T-Helper CD4+ Records
Antibody Records VRC01 (2163), VRC02 (2164), VRC03 (2165), NIH45-46 (2580), VRC06 (2660), VRC06b (2661), NIH45-46G54W (2821), VRC07 (3059), VRC01-30fH/19fL (3062), VRC01-30fH/10fL (3063), VRC01-8fH/19fL (3065), VRC01-8fH/10fL (3066), VRC01-8fH/6fL (3067), VRC01-5fH/10fL (3068), VRC01-5fH/6fL (3069), VRC01-5fH/0fL (3070), VRC01-0fH/0fL (3071), gVRC-H1dC38/VRC01L (3118), VRC07-523-LS (3156), VRC07-501-LS (3158), VRC07-508-LS (3159), VRC07-544-LS (3160), 45-46m2 (3161), 45-46m7 (3162), NIH45-46G54F (3165), NIH45-46G54Y (3166), 45-46m25 (3167), 45-46m28 (3175), VRC08 (3279), VRC01-LS (3313), VRC08c (3318), VRC01b (3338), VRC01c (3339), VRC01d (3341), VRC01e (3342), VRC01f (3343), VRC01g (3344), VRC01h (3345), VRC01i (3346), VRC01j (3347), VRC07b (3348), VRC07c (3349), VRC07d (3350), VRC07e (3351), VRC07f (3352), VRC03b (3353), VRC03d (3354), VRC03e (3355), VRC03f (3356), VRC03g (3357), VRC03h (3358), VRC03i (3359), VRC06c (3360), VRC06d (3361), VRC06e (3362), VRC06f (3363), VRC06g (3364), VRC06h (3365), VRC08d (3366), VRC08e (3367), NIH45-177 (3368), NIH45-243 (3369), VRC07xPG9-16 (3372), VRC07-αCD3 (3469), VRC01-iMab (3568), NIH45-46-iMab (3572), GL-VRC01 (3836), Bi-NAb (3921), VRC01/PGDM1400-10E8v4 (3955), Bi-ScFv (3958), Tri-NAb (3959), polyclonal NIH45 (3967), NIH45-46WPY (4011), NIH45-46WY (4012), DRVIA7H-VRC01L (4091), VRC01H-DRVIA7L (4113)
Sequence Database Patient ID Record 50341
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