HIV molecular immunology database

 

Patient Detail

Patient Code Donor CH505 (703010505)
Patient Sex Male
Risk Factor Heterosexual (SH)
Infection Country MW
Infection City
Infection Year 2008
HLA Type A*30, A*30, B*42:02, B*57:03:01, C*17, C*18
Patient Ethnicity African
Progression
Species human
Patient Note African donor enrolled approximately 4 weeks after infection and followed for over 6 years. During this time viral load ranged from 14,460 to 847,279 copies/ml (median = 173,667 copies/ml), and CD4 counts ranged from 69 to 431 cells/mm3 (median = 294 cells/ mm3). A single founder virus is estimated to have established HIV-1 clade C with development of autologous neutralizing antibodies at 14 weeks; Abs CH103,CH104,CH105,CH106 isolated 136 weeks post-infection. Antibody CH235 was isolated from the patient's week 41-peripheral blood memory B cells in culture.
CTL CD8+ Records 59059, 59060
T-Helper CD4+ Records
Antibody Records CH103 (2861), CH104 (2862), CH105 (2863), CH106 (2864), IA1 (3176), IA2 (3177), IA3 (3178), IA4 (3179), IA5 (3180), IA6 (3181), IA7 (3182), IA8 (3183), CH103 UCA (3184), CH235 (3185), CH236 (3186), CH239 (3187), CH240 (3188), CH241 (3189), CH186 (3190), CH187 (3191), CH188 (3192), CH200 (3193), DH151 (3234), DH228 (3235), CH235.9 (3291), CH235.12 (3292), CH243 (3374), CH244 (3375), CH245 (3376), CH247 (3377), CH248 (3378), 1AH92U (3380), CH235.7 (3381), CH235.10 (3382), CH235.11 (3383), CH235.13 (3384)
Sequence Database Patient ID Record 56552
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