HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 201927

Download this epitope record as JSON.

HXB2 Location Pol(891-905)
Integrase(176-190)
DNA(4755..4799)
Pol Epitope Map
Author Location Pol
Epitope VQMAVFIHNFKRKGG Epitope Alignment
VQMAVFIHNFKRKGG epitope logo
Epitope Name Pol892
Species (MHC/HLA) humanized mouse, mouse
Immunogen vaccine
Experimental methods CD4 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords vaccine-induced immune responses

Notes

References

Liu2017 Haitao Liu, Wei Shen, Jiayi Shu, Zhihua Kou, and Xia Jin. A Novel Polyepitope Vaccine Elicited HIV Peptide Specific CD4+ T Cell Responses in HLA-A2/DRB1 Transgenic Mice. PLoS One, 12(9):1-11, 2017. PubMed ID: 28863168. Show all entries for this paper.


Displaying record number 201983

Download this epitope record as JSON.

HXB2 Location Pol(891-905)
Integrase(176-190)
DNA(4755..4799)
Pol Epitope Map
Author Location Pol
Epitope VQMAVFIHNFKRKGG Epitope Alignment
VQMAVFIHNFKRKGG epitope logo
Epitope Name Pol 892
Species (MHC/HLA) human, mouse
Immunogen in vitro stimulation or selection, HIV-1 infection, vaccine
Country China
Experimental methods CD4 T-cell Elispot - IFNγ, HLA binding, Other
Keywords binding affinity, vaccine-induced immune responses, kinetics, vaccine antigen design

Vaccine Details

Vaccine type polyepitope, E. coli recombinant protein
Vaccine component Env, Gag, Nef, Pol

Notes

References

Shu2020 Jiayi Shu, Wei Shen, Haitao Liu, Yiqing Zhou, Jianhui Li, Yan Zhuang, Zhenghui Huang, Shigang Yin, Lubin Jiang, Yongtao Sun, Xia Jin, and Jianqing Xu. The Immunologic Dominance of an Epitope within a Rationally Designed Poly-Epitope Vaccine Is Influenced by Multiple Factors. Vaccine, 38(14):2913-2924, 23 Mar 2020. PubMed ID: 32127225. Show all entries for this paper.


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