HIV molecular immunology database

 

Search T Helper/CD4+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 491

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HXB2 Location gp160(606-620)
gp41(95-109)
DNA(8040..8084)
gp160 Epitope Map
Author Location gp41( UG92005)
Epitope TNVPWNASWSNKSLE Epitope Alignment
TNVPWNASWSNKSLE epitope logo
Species (MHC/HLA) mouse(H-2 IAb)
Immunogen vaccine
Experimental methods  
Keywords subtype comparisons, epitope processing, TCR usage

Vaccine Details

Vaccine type DNA, protein, vaccinia
Vaccine strain B clade 1007, D clade UG92005
Vaccine component gp140
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Surman2001 S. Surman, T. D. Lockey, K. S. Slobod, B. Jones, J. M. Riberdy, S. W. White, P. C. Doherty, and J. L. Hurwitz. Localization of CD4+ T Cell Epitope Hotspots to Exposed Strands of HIV Envelope Glycoprotein Suggests Structural Influences on Antigen Processing. Proc. Natl. Acad. Sci. U.S.A., 98(8):4587-4592, 10 Apr 2001. URL: http://www.pnas.org/cgi/content/full/98/8/4587. PubMed ID: 11287644. Show all entries for this paper.


Displaying record number 200877

Download this epitope record as JSON.

HXB2 Location gp160(606-620)
gp41(95-109)
DNA(8040..8084)
gp160 Epitope Map
Author Location gp41( 1035)
Epitope TNVPWNASWSNKSLE Epitope Alignment
TNVPWNASWSNKSLE epitope logo
Subtype B
Species (MHC/HLA) mouse
Immunogen vaccine
Experimental methods T-cell Elispot
Keywords epitope processing, vaccine-induced immune responses, escape, TCR usage

Vaccine Details

Vaccine type vaccinia prime with gp120 boost
Vaccine strain B clade 1035
Vaccine component Env
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Zhan2003 X. Zhan, K. S. Slobod, S. Surman, S. A. Brown, T. D. Lockey, C. Coleclough, P. C. Doherty, and J. L. Hurwitz. Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein. J. Virol., 77(7):4231-4236, Apr 2003. PubMed ID: 12634380. Show all entries for this paper.


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